scholarly journals Role of intraoperative cytology combined with histology in detecting continuous and skip type intraductal cancer existence for intraductal papillary mucinous carcinoma of the pancreas

Cancer ◽  
2006 ◽  
Vol 107 (11) ◽  
pp. 2567-2575 ◽  
Author(s):  
Hidetoshi Eguchi ◽  
Osamu Ishikawa ◽  
Hiroaki Ohigashi ◽  
Yo Sasaki ◽  
Terumasa Yamada ◽  
...  
Keyword(s):  
Mucinous Carcinoma ◽  
Carcinoma Of The Pancreas ◽  
Intraoperative Cytology ◽  
Intraductal Cancer

Cytologic Study of Noninvasive Intraductal Papillary-Mucinous Carcinoma of the Pancreas

2002 ◽  
Vol 46 (3) ◽  
pp. 519-526 ◽  
Author(s):  
Hitoshi Hara ◽  
Koichi Suda ◽  
Toshio Oyama
Keyword(s):  
Mucinous Carcinoma ◽  
Carcinoma Of The Pancreas ◽  
Cytologic Study

The role of adjuvant intra-arterial chemotherapy (IAC) after pancreatic resection for ductal carcinoma of the pancreas

2000 ◽  
Vol 118 (4) ◽  
pp. A1517
Author(s):  
Calogero Iacono ◽  
Maurizio Cantore ◽  
Mauro Pagani ◽  
Luca Bortolasi ◽  
Andrea Mambrini ◽  
...  
Keyword(s):  
Pancreatic Resection ◽  
Ductal Carcinoma ◽  
Carcinoma Of The Pancreas

Recurrent Invasive Intraductal Papillary Mucinous Carcinoma of the Pancreas Mimicking Pott Disease: Review of the Literature

Pancreas ◽  
2006 ◽  
Vol 32 (3) ◽  
pp. 321-324 ◽  
Author(s):  
Carlos U. Corvera ◽  
Ward J. Dunnican ◽  
Leslie H. Blumgart ◽  
Michael D'Angelica
Keyword(s):  
Mucinous Carcinoma ◽  
Review Of The Literature ◽  
Carcinoma Of The Pancreas

scholarly journals The Role of Intraoperative Cytology in the Diagnostic Evaluation of Ovarian Neoplasms

2012 ◽  
Vol 56 (5) ◽  
pp. 467-473 ◽  
Author(s):  
Mohammad Shahid ◽  
Sufian Zaheer ◽  
Aysha Mubeen ◽  
Khaliqur Rahman ◽  
Rana K. Sherwani
Keyword(s):  
Ovarian Neoplasms ◽  
Diagnostic Evaluation ◽  
Intraoperative Cytology

Role of frozen section associated with intraoperative cytology in comparison to FNA and FS alone in the management of thyroid nodules

2007 ◽  
Vol 33 (6) ◽  
pp. 769-775 ◽  
Author(s):  
F. Basolo ◽  
C. Ugolini ◽  
A. Proietti ◽  
P. Iacconi ◽  
P. Berti ◽  
...  
Keyword(s):  
Thyroid Nodules ◽  
Frozen Section ◽  
Intraoperative Cytology

Pseudomyxoma Peritonei Caused by Acute Pancreatitis in Intraductal Papillary Mucinous Carcinoma of the Pancreas

Pancreas ◽  
2006 ◽  
Vol 32 (2) ◽  
pp. 223-224 ◽  
Author(s):  
Hiroshi Imaoka ◽  
Kenji Yamao ◽  
Ahmed A. S. Salem ◽  
Nobumasa Mizuno ◽  
Kuniyuki Takahashi ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Pseudomyxoma Peritonei ◽  
Mucinous Carcinoma ◽  
Carcinoma Of The Pancreas

scholarly journals A Case of Intraductal Papillary Mucinous Carcinoma of the Pancreas

Pancreas ◽  
2009 ◽  
Vol 38 (5) ◽  
pp. 489
Author(s):  
Junji Komori ◽  
Nobuhiko Shinkura ◽  
Akira Mituyoshi ◽  
Masahisa Kyougoku ◽  
Masazumi Zaima
Keyword(s):  
Mucinous Carcinoma ◽  
Carcinoma Of The Pancreas

scholarly journals Ovarian metastases of pancreatic adenocarcinoma: clinical presentation, role of surgery, and potential value of the mutational profile for the differential diagnosis with primary mucinous ovarian carcinoma

2021 ◽  
Vol 13 ◽  
pp. 175883592110534
Author(s):  
Alice de Malet ◽  
Magali Svrcek ◽  
Anne Kerbaol ◽  
Nathalie Theou-Anton ◽  
Sandra Granier ◽  
...  
Keyword(s):  
Pancreatic Adenocarcinoma ◽  
Surgical Resection ◽  
Mucinous Carcinoma ◽  
Significant Morbidity ◽  
Ovarian Metastases ◽  
Histological Data ◽  
Next Generation Sequencing Ngs ◽  
Mucinous Ovarian Carcinoma ◽  
Pancreatic Origin

Background: Ovarian metastases (OM) of pancreatic adenocarcinoma (PA) (OM-PA) can mimic primary ovarian mucinous carcinoma (POMC) on imaging and histology. These metastases are often symptomatic and not highly chemosensitive, so that oophorectomy may be considered. Aims: The aims of this study were to compare the characteristics of OM-PA and POMC, and discuss the role of surgery. Patients and Methods: Clinical, imaging, and histological data of patients with OM-PA and POMC (2000–2017) in three tertiary centers were reviewed. Twenty-six genes were analyzed by next generation sequencing (NGS) on both primary PA and OM-PA. Results: Twenty-two women with OM-PA ( n = 13, 11 with surgical resection) or POMC ( n = 9) were selected. OM-PA were smaller than POMC ( p = 0.02); imaging, histological, and immunohistochemistry data did not clearly differentiate OM-PA from POMC in 12 of 22 cases (54%). Seven PA/OM-PA pairs were analyzed, and a concordant KRAS mutation was identified in all cases. In four OM-PA, concordant mutations were also found in TP53 ( n = 3), SMAD4 ( n = 1), MET ( n = 1), and PDGFRA ( n = 1) genes. The aim of oophorectomy in 11 OM-PA was for antalgic ( n = 6) or curative ( n = 5) intent. Pain improved in 4/6 of the former patients, but 2/6 had significant morbidity, and 2/6 died of rapid tumor progression. After oophorectomy, median progression-free and overall survivals were 6 (0–11) and 8 months (1–131), respectively. Conclusion: Analysis of mutation profiles in both primary PA and ovarian tumors, especially KRAS, can help to determine the pancreatic origin of OM-PA. Surgical resection of OM-AP in highly selected patients may improve pelvic symptoms but may also cause significant morbidity. The benefit to survival requires further studies.

scholarly journals Evaluating intraoperative cytology with histopathology diagnosis and its importance in ovarian tumors

2020 ◽  
Vol 10 (1) ◽  
pp. 1630-1634
Author(s):  
Karishma Malla Vaidya ◽  
Bigya Shrestha ◽  
Runa Jha ◽  
Binit Shrestha ◽  
Aasiya Rajbhandari ◽  
...  
Keyword(s):  
Predictive Value ◽  
Ovarian Neoplasms ◽  
Ovarian Neoplasm ◽  
Imprint Cytology ◽  
Frozen Sections ◽  
Intraoperative Diagnosis ◽  
Touch Imprint Cytology ◽  
Intraoperative Cytology ◽  
Benign Ovarian Neoplasm

Background: Touch/ imprint cytology has been utilized for intraoperative evaluations of tumors to complement frozen sections in order to reach diagnosis prior to histopathology diagnosis. The main aim of this study is to find role of touch imprint in determining histopathology diagnosis of ovarian neoplasm. Materials and Methods: All together one hundred three cases were evaluated using both touch/imprint and histopathology diagnosis. The histopathology diagnoses consisted of Benign (n=85), borderline (n=4), and malignant (n=12). Touch imprint cytology consists of Negative for malignancy (n=90), Positive for malignancy (n=11) and inadequate (n=2). Inadequate smear was excluded from the study. Results: Both touch / imprint cytology were able to diagnose benign and malignant ovarian neoplasm. Out of 103 cases, in cytology showed 89.1% patients were negative and 10.9% patients were positive. Histopathology shows 84.2% of benign ovarian neoplasm, 3.9% borderline neoplasm and 11.9% of malignant. Diagnostic accuracy of touch/ imprint was 99% with sensitivity 100% and specificity was 91.67%. Positive predictive value was 98.89% and negative predictive value was 100%. Conclusion: Touch/ imprint cytology examination is simple, rapid and useful test in evaluation of ovarian neoplasms. It plays very important role in preliminary intraoperative diagnosis of benign and malignant ovarian neoplasms. 

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