Hearing preservation after gamma knife stereotactic radiosurgery of vestibular schwannoma

Cancer ◽  
2005 ◽  
Vol 104 (3) ◽  
pp. 580-590 ◽  
Author(s):  
Sun Ha Paek ◽  
Hyun-Tai Chung ◽  
Sang Soon Jeong ◽  
Chul-Kee Park ◽  
Chae-Yong Kim ◽  
...  
Keyword(s):  
Stereotactic Radiosurgery ◽  
Gamma Knife ◽  
Vestibular Schwannoma ◽  
Hearing Preservation ◽  
Gamma Knife Stereotactic Radiosurgery

Place of Gamma Knife Stereotactic Radiosurgery in Grade 4 Vestibular Schwannoma Based on Case Series of 86 Patients with Long-Term Follow-Up

2018 ◽  
Vol 114 ◽  
pp. e1192-e1198 ◽  
Author(s):  
Michel Lefranc ◽  
Leila Maria Da Roz ◽  
Anne Balossier ◽  
Jean Marc Thomassin ◽  
Pierre Hugue Roche ◽  
...  
Keyword(s):  
Stereotactic Radiosurgery ◽  
Gamma Knife ◽  
Vestibular Schwannoma ◽  
Case Series ◽  
Long Term Follow Up ◽  
Gamma Knife Stereotactic Radiosurgery

Tumor volume threshold for achieving improved conformity in VMAT and Gamma Knife stereotactic radiosurgery for vestibular schwannoma

2015 ◽  
Vol 115 (2) ◽  
pp. 229-234 ◽  
Author(s):  
Hyun Kim ◽  
Peter Potrebko ◽  
Amanda Rivera ◽  
Haisong Liu ◽  
Harriet B. Eldredge-Hindy ◽  
...  
Keyword(s):  
Stereotactic Radiosurgery ◽  
Gamma Knife ◽  
Vestibular Schwannoma ◽  
Tumor Volume ◽  
Gamma Knife Stereotactic Radiosurgery

scholarly journals Radiomic assessment of the progression of acoustic neuroma after gamma knife stereotactic radiosurgery

2019 ◽  
Vol 9 (2) ◽  
pp. 1
Author(s):  
Ganesh Narayanasamy ◽  
Geoffrey Zhang ◽  
Eric Siegel ◽  
Graham Campbell ◽  
Eduardo G. Moros ◽  
...  
Keyword(s):  
Stereotactic Radiosurgery ◽  
Gamma Knife ◽  
Acoustic Neuroma ◽  
Roc Analysis ◽  
Operating Characteristic ◽  
Hearing Preservation ◽  
Magnetic Resonance Images ◽  
Acoustic Neuromas ◽  
Gray Tone ◽  
Gamma Knife Stereotactic Radiosurgery

Introduction: The aim of this study was to determine whether radiomic features measured at baseline in Magnetic Resonance images (MRI) of acoustic neuromas (AN) can predict Gamma Knife (GK) treatment outcome.Methods: The study was conducted on pre- and post-GK MRI-T2 scans of 32 patients with AN who underwent stereotactic radiosurgery (SRS) for 12 Gy dose. Radiomic features extracted include Intensity, Fractals, Laplacian of Gaussian and textural Co-Occurrence, Run-length (RL), Size Zone, and Neighborhood Gray-Tone Difference matrices (NGTDM) features. Subjects were classified as treatment failures (TF) if tumor volume increased > 10%. Pre- and post-SRS audiology reports were utilized in hearing evaluation.Results: Fifteen subjects (47%) qualified as TFs. In univariate receiver operating characteristic (ROC) analysis, two radiomicfeatures, complexity in NGTDM and run percentage in RL, displayed areas under curves of > 0.65.Conclusion: This initial radiomic study establishes features that illustrates the prognostic ability of the SRS treatment in acousticneuroma. Hearing preservation was achieved in a majority of acoustic neuroma patients treated in Gamma Knife.

The Effect of Prescription Isodose Variation on Tumor Control and Toxicities in Stereotactic Radiosurgery for Sporadic Vestibular Schwannoma: Propensity Score-Matched Case–Control Study

2021 ◽  
Author(s):  
Achiraya Teyateeti ◽  
Christopher S. Graffeo ◽  
Avital Perry ◽  
Eric J. Tryggestad ◽  
Paul D. Brown ◽  
...  
Keyword(s):  
Propensity Score ◽  
Stereotactic Radiosurgery ◽  
Vestibular Schwannoma ◽  
Hearing Preservation ◽  
Tumor Control ◽  
Gamma Knife Stereotactic Radiosurgery ◽  
The Impact ◽  
Prescription Isodose

Abstract Objective Vestibular schwannoma (VS) treated with Gamma Knife stereotactic radiosurgery (SRS) was typically performed at 50% isodose line (IDL50); however, the impact of IDL variation on outcomes is poorly understood. This study aimed to compare tumor control (TC) and toxicities between treatment at 40% (IDL40) and 50% (IDL50). Methods and Materials Sporadic/unilateral VS patients treated with SRS dose 12 to 14 Gy and prescription isodose volume ≤10cm3 were included. Propensity score matching was applied to IDL40 cohort to generate an IDL50 companion cohort, adjusting for age and prescription isodose volume. After exclusion of patients with follow-up <24 months, there were 30 and 28 patients in IDL40 and IDL50 cohorts, respectively. Results Median follow-up time was 96 months (24–225 months). Actuarial and radiographic TC rates were 91.8% and clinical TC was 96.2% both at 5 and 10 years. TC was higher in IDL40 cohort but not significant (96.4 vs. 86.7%; p = 0.243). Hearing preservation (HP) rates were 71.9 and 39.2% at 5- and 10-year intervals, with significantly higher rates of HP noted in IDL40 cohort (83.3 vs. 57.1% at 5-year interval; 62.5 vs. 11.4% at 10-year interval; p = 0.017). Permanent facial neuropathy occurred in two patients, both from the IDL50 cohort (3.5%). Rates of post-SRS steroid treatment or shunt placement for hydrocephalus were slightly higher in IDL50 patients (6.9 vs. 17.9%; p = 0.208 and 3.3 vs. 7.1%; p = 0.532). Conclusion For treatment of VS with SRS, dose prescription at IDL40 or IDL50 provides excellent long-term TC and toxicity profiles. IDL40 may be associated with improved long-term HP.

scholarly journals Radiomic assessment of the progression of acoustic neuroma after gamma knife stereotactic radiosurgery

2019 ◽  
Vol 9 (2) ◽  
pp. 1
Author(s):  
Ganesh Narayanasamy ◽  
Geoffrey Zhang ◽  
Eric Siegel ◽  
Graham Campbell ◽  
Eduardo G. Moros ◽  
...  
Keyword(s):  
Stereotactic Radiosurgery ◽  
Gamma Knife ◽  
Acoustic Neuroma ◽  
Roc Analysis ◽  
Operating Characteristic ◽  
Hearing Preservation ◽  
Magnetic Resonance Images ◽  
Acoustic Neuromas ◽  
Gray Tone ◽  
Gamma Knife Stereotactic Radiosurgery

Introduction: The aim of this study was to determine whether radiomic features measured at baseline in Magnetic Resonance images (MRI) of acoustic neuromas (AN) can predict Gamma Knife (GK) treatment outcome.Methods: The study was conducted on pre- and post-GK MRI-T2 scans of 32 patients with AN who underwent stereotactic radiosurgery (SRS) for 12 Gy dose. Radiomic features extracted include Intensity, Fractals, Laplacian of Gaussian and textural Co-Occurrence, Run-length (RL), Size Zone, and Neighborhood Gray-Tone Difference matrices (NGTDM) features. Subjects were classified as treatment failures (TF) if tumor volume increased > 10%. Pre- and post-SRS audiology reports were utilized in hearing evaluation.Results: Fifteen subjects (47%) qualified as TFs. In univariate receiver operating characteristic (ROC) analysis, two radiomicfeatures, complexity in NGTDM and run percentage in RL, displayed areas under curves of > 0.65.Conclusion: This initial radiomic study establishes features that illustrates the prognostic ability of the SRS treatment in acousticneuroma. Hearing preservation was achieved in a majority of acoustic neuroma patients treated in Gamma Knife.

Sign in / Sign up

Export Citation Format

Share Document