scholarly journals Local lymph node involvement does not predict poor outcome in pediatric renal cell carcinoma

Cancer ◽  
2005 ◽  
Vol 103 (6) ◽  
pp. 1317-1318 ◽  
Author(s):  
Andrew Renshaw
Keyword(s):  
Renal Cell Carcinoma ◽  
Lymph Node ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Lymph Node Involvement ◽  
Poor Outcome ◽  
Node Involvement ◽  
Pediatric Renal Cell Carcinoma ◽  
Local Lymph Node

Local lymph node involvement in pediatric renal cell carcinoma: A report from the Italian TREP project

2008 ◽  
Vol 51 (4) ◽  
pp. 475-478 ◽  
Author(s):  
Paolo Indolfi ◽  
Gianni Bisogno ◽  
Giovanni Cecchetto ◽  
Filippo Spreafico ◽  
Gian Luca De Salvo ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Lymph Node ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Lymph Node Involvement ◽  
Node Involvement ◽  
Pediatric Renal Cell Carcinoma ◽  
Local Lymph Node

Is local lymph node involvement a prognostic factor in paediatric renal cell carcinoma?

2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 20014-20014
Author(s):  
P. Indolfi ◽  
G. Bisogno ◽  
G. Cecchetto ◽  
A. Ferrari ◽  
L. Piva ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Lymph Node ◽  
Lymph Nodes ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Lymph Node Involvement ◽  
Number Of Patients ◽  
Node Involvement ◽  
Local Lymph Node

20014 Background: RCC in childhood is rare. Children with RCC tend to have a similar overall prognosis when compared with adults, where prognosis worsens with increasing stage, although direct comparisons of adult and paediatric data isn’t easy. The aim of our study is to identify the prognostic significance of local lymph node involvement in children with Renal Cell Carcinoma (RCC). Methods: On the basis of a retrospective study, the recently founded Italian Association for Paediatric Hematology and Oncology-Rare Tumors Paediatric Age (AIEOP-TREP) identified 16 patients (9 females) with RCC and local lymph node involvement at 10 of these centers. The cases were observed among 59 paediatric RCC, corresponding to 27.1% of RCC presenting in Italy from January 1973 to May 2006. Results: Overall, 9 patients were alive and disease free at last follow-up: eight patients had regional lymph node dissection (RLND) from the diaphragm at the aortic bifurcation, and one had the para-aortic lymph nodes removal. Six patients died: one had RLND (died from progression of disease), three had the renal hilum lymph nodes removal, and two the para-aortic lymph nodes dissection. One patient was lost to follow-up after relapse: this patient had para-aortic lymph node removal at diagnosis. Estimated 25-year DFS and OS rates for all patients were 64.2% and 50.5%, respectively. Given the small number of patients, little can be said about the value, if any, of adjuvant immunotherapy in this group of RCC. Conclusions: Children with lymph node positive RCC had a relatively unfavourable long- term prognosis. In our experience the RLND improves the prognosis. Further investigation of the biologic differences is warranted. Because of the very low incidence of paediatric RCC, an international clinical trial will be required to establish optimal therapy for children with RCC. No significant financial relationships to disclose.

Renal Angiomyolipoma: Report of three cases with Regional Lymph Node Involvement and/or with Renal Cell Carcinoma

1995 ◽  
Vol 81 (6) ◽  
pp. 469-474 ◽  
Author(s):  
György Csanaky ◽  
Zoltán Szereday ◽  
Tamás Magyarlaki ◽  
Gábor Méhes ◽  
Tamás Herbert ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Lymph Node ◽  
Lymph Nodes ◽  
Cell Carcinoma ◽  
Tuberous Sclerosis ◽  
Malignant Transformation ◽  
Renal Cell ◽  
Dna Ploidy ◽  
Lymph Node Involvement ◽  
Node Involvement

Aims and background Angiomyolipomas (AMLs) are benign hamartoid tumors which frequently occur in tuberous sclerosis (TS). They may be manifest at different organ sites such as kidneys, lymph nodes, liver and lung and may be associated with renal cell carcinoma (RCC). The nature of multiple organ involvement in AML (metastasis versus multicentric synchronous tumors), the malignant transformation and the relation of AML to RCC have not been sufficiently clarified. Study design Three cases of renal AMLs in patients with tuberous sclerosis associated with lymphangioleiomyomatosis of the paraaortic lymph nodes and/or with RCC are reported. The concise clinical history of the patients as well as the findings of histology, immunohistochemistry and quantitative DNA analysis are presented. Results The multicentric form of AML and coincidence of renal AML and RCC were observed in 2 patients. AML and RCC were found within the same focus in one of the cases. RCCs were either aneuploid or “near diploid”, whereas one of the multicentric AMLs showed a discordant DNA ploidy pattern, namely aneuploidy in the kidney and diploidy in the lymph nodes. Conclusions The presented cases (all of them underwent periaortic lymphadenectomy) suggest that lymph node involvement in renal AML may be more frequent than expected (1-2% of all AMLs) on the basis of the few reported cases. The discordant DNA ploidy (renal versus lymph node lesions) observed in one of the cases with multicentric AML implies synchronous tumor growth at different sites rather than metastatic disease. The intimate coexistance of RCC and AML (RCC revealed by immunohistochemistry within a larger mass of renal AML) may indicate that malignant transformation of an AML should only be accepted, if such a coincidence is unequivocally excluded.

Renal Angiomyolipoma Associated with Lymph Node Involvement and Renal Cell Carcinoma in Patients with Tuberous Sclerosis

1989 ◽  
Vol 141 (4) ◽  
pp. 930-932 ◽  
Author(s):  
Robert S. Taylor ◽  
David B. Joseph ◽  
Edward C. Kohaut ◽  
Edward R. Wilson ◽  
Anton J. Bueschen
Keyword(s):  
Renal Cell Carcinoma ◽  
Lymph Node ◽  
Cell Carcinoma ◽  
Tuberous Sclerosis ◽  
Renal Cell ◽  
Lymph Node Involvement ◽  
Renal Angiomyolipoma ◽  
Node Involvement

scholarly journals PD04-01 RENAL CELL CARCINOMA WITH ISOLATED LYMPH NODE INVOLVEMENT: NATURAL HISTORY AND PREDICTORS OF ONCOLOGIC OUTCOMES

2016 ◽  
Vol 195 (4S) ◽  
Author(s):  
Boris Gershman ◽  
Daniel Moreira ◽  
R. Houston Thompson ◽  
Stephen Boorjian ◽  
Christine Lohse ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Lymph Node ◽  
Natural History ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Lymph Node Involvement ◽  
Oncologic Outcomes ◽  
Node Involvement

Renal Cell Carcinoma with Isolated Lymph Node Involvement: Long-term Natural History and Predictors of Oncologic Outcomes Following Surgical Resection

2017 ◽  
Vol 72 (2) ◽  
pp. 300-306 ◽  
Author(s):  
Boris Gershman ◽  
Daniel M. Moreira ◽  
R. Houston Thompson ◽  
Stephen A. Boorjian ◽  
Christine M. Lohse ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Lymph Node ◽  
Natural History ◽  
Cell Carcinoma ◽  
Surgical Resection ◽  
Renal Cell ◽  
Lymph Node Involvement ◽  
Oncologic Outcomes ◽  
Node Involvement
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