scholarly journals Identification of progressive cervical epithelial cell abnormalities using DNA image cytometry

Cancer ◽  
2004 ◽  
Vol 102 (6) ◽  
pp. 373-379 ◽  
Author(s):  
Hans Juergen Grote ◽  
Huy V. Q. Nguyen ◽  
Anand Gilbert Leick ◽  
Alfred Böcking
2002 ◽  
Vol 24 (1) ◽  
pp. 1-4 ◽  
Author(s):  
A. G. J. M. Hanselaar

Cytological examination is a valuable diagnostic tool in case of a serous effusion. The firstmanifestation of malignancy may be an effusion of the pleural, pericardial, or peritoneal cavity, especially in carcinoma of the ovary, or lung, and malignant mesothelioma. In other malignancies effusions may occur in the course of the disease. The contribution by Motherby et al. in this issue of ACP focuses on the contribution of image and flow cytometry to establish the presence or absence of malignancy in serous effusions [16]. They point out that the sensitivity of DNA image cytometry in equivocal effusions may be as high as 87.5%, and that for the detection of malignancy, DNA image cytometry is superior to flow cytometry.


1999 ◽  
Vol 105 (4) ◽  
pp. 960-965 ◽  
Author(s):  
Susanne Widell ◽  
Robert Hast ◽  
Gert Auer ◽  
Christopher Cox ◽  
John M. Bennett

1990 ◽  
Vol 94 (2) ◽  
pp. 254-260 ◽  
Author(s):  
Wilhelm Stolz ◽  
Thomas Vogt ◽  
Otto Braun-falco ◽  
Wolfgang Abmayr ◽  
Fritjof Eckert ◽  
...  

2000 ◽  
Vol 21 (3-4) ◽  
pp. 149-159 ◽  
Author(s):  
G. Haroske ◽  
Francoise Giroud ◽  
K. D. Kunze ◽  
W. Meyer

An increasing need for flexible consultation between pathologists, including the application of fast evolving supplementary technologies, has been identified during the last years. Although pathology is already one of the most advanced application of telemedicine there is more to come from the fast evolution towards computerized microscope image analysis: A reproducible quantification of measurable descriptors of the lesions in cells and tissues (so‐called biological markers) is an indispensable adjunct to routine diagnostic application. Among such quantitative methods DNA image cytometry is increasingly applied by pathologists for assistance in diagnostics.As for other pathological issues, too, a reference center for the clinical application of DNA image cytometry might be therefore of utmost value for pathologists using that method.Based on advanced telematic technologies, a Virtual Reference and Certification Center (VRCC) could be installed for certifying the cytometry hardware and software, the analytical procedures, and the basic interpretation of the results. It will be designed to be operated as a non‐attended service, based on quantification servers accessible via Internet round the clock. The VRCC will supply appropriate standardization and normalization materials and run a GroupWare platform for consensus making by experts.


1998 ◽  
Vol 138 (4) ◽  
pp. 706-708 ◽  
Author(s):  
Kiehl ◽  
Richter ◽  
Erdelkamp ◽  
Herbst ◽  
Kapp ◽  
...  

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