Complex of urokinase-type plasminogen activator with its type 1 inhibitor predicts poor outcome in 576 patients with lymph node–negative breast carcinoma

Peggy Manders; Vivianne C. G. Tjan-Heijnen; Paul N. Span; Nicolai Grebenchtchikov; Anneke Geurts-Moespot; Doorlène T. H. van Tienoven; Louk V. A. M. Beex; Fred C. G. J. Sweep

doi:10.1002/cncr.20374

Complex of urokinase-type plasminogen activator with its type 1 inhibitor predicts poor outcome in 576 patients with lymph node–negative breast carcinoma

Cancer ◽

10.1002/cncr.20374 ◽

2004 ◽

Vol 101 (3) ◽

pp. 486-494 ◽

Cited By ~ 29

Author(s):

Peggy Manders ◽

Vivianne C. G. Tjan-Heijnen ◽

Paul N. Span ◽

Nicolai Grebenchtchikov ◽

Anneke Geurts-Moespot ◽

...

Keyword(s):

Lymph Node ◽

Breast Carcinoma ◽

Plasminogen Activator ◽

Node Negative ◽

Poor Outcome ◽

Type Plasminogen Activator ◽

Urokinase Type Plasminogen Activator

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Randomized Adjuvant Chemotherapy Trial in High-Risk, Lymph Node-Negative Breast Cancer Patients Identified by Urokinase-Type Plasminogen Activator and Plasminogen Activator Inhibitor Type 1

JNCI Journal of the National Cancer Institute ◽

10.1093/jnci/93.12.913 ◽

2001 ◽

Vol 93 (12) ◽

pp. 913-920 ◽

Cited By ~ 284

Author(s):

F. Janicke ◽

A. Prechtl ◽

C. Thomssen ◽

N. Harbeck ◽

C. Meisner ◽

...

Keyword(s):

Plasminogen Activator ◽

Plasminogen Activator Inhibitor ◽

Breast Cancer Patients ◽

Node Negative ◽

Node Negative Breast Cancer ◽

Type Plasminogen Activator ◽

Urokinase Type Plasminogen Activator ◽

Inhibitor Type ◽

Activator Inhibitor Type

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Plasminogen Activator Inhibitor Type 1 is the Most Significant of the Usual Tissue Prognostic Factors in Node-Negative Breast Ductal Adenocarcinoma Independent of Urokinase-Type Plasminogen Activator

Clinical Breast Cancer ◽

10.3816/cbc.2008.n.018 ◽

2008 ◽

Vol 8 (2) ◽

pp. 168-177 ◽

Cited By ~ 15

Author(s):

Françoise Descotes ◽

Benjamin Riche ◽

Simone Saez ◽

Guy De Laroche ◽

Jean Datchary ◽

...

Keyword(s):

Plasminogen Activator ◽

Plasminogen Activator Inhibitor ◽

Ductal Adenocarcinoma ◽

Node Negative ◽

Type Plasminogen Activator ◽

Urokinase Type Plasminogen Activator ◽

Inhibitor Type ◽

Activator Inhibitor Type ◽

Activator Inhibitor

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Urokinase type plasminogen activator and inhibitor type-1 plasma levels in colorectal cancer

Gastroenterology ◽

10.1016/s0016-5085(01)82981-4 ◽

2001 ◽

Vol 120 (5) ◽

pp. A599-A600 ◽

Cited By ~ 1

Author(s):

L HERSZENYI ◽

F FARINATI ◽

G ISTVAN ◽

M PAOLI ◽

G ROVERONI ◽

...

Keyword(s):

Colorectal Cancer ◽

Plasminogen Activator ◽

Plasma Levels ◽

Type Plasminogen Activator ◽

Urokinase Type Plasminogen Activator ◽

Inhibitor Type

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Tumor necrosis factor-α regulates mRNA for urokinase-type plasminogen activator and type-1 plasminogen activator inhibitor in human neoplastic cell lines

Molecular and Cellular Endocrinology ◽

10.1016/0303-7207(89)90192-5 ◽

1989 ◽

Vol 61 (1) ◽

pp. 87-96 ◽

Cited By ~ 17

Author(s):

Birgitte Georg ◽

Eirik Helseth ◽

Leif R. Lund ◽

Toril Skandsen ◽

Andrea Riccio ◽

...

Keyword(s):

Plasminogen Activator ◽

Tumor Necrosis ◽

Plasminogen Activator Inhibitor ◽

Neoplastic Cell ◽

Type Plasminogen Activator ◽

Urokinase Type Plasminogen Activator ◽

Factor Α ◽

Activator Inhibitor ◽

Necrosis Factor

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A high number of tumor free axillary lymph nodes from patients with lymph node negative breast carcinoma is associated with poor outcome

Cancer ◽

10.1002/(sici)1097-0142(20000101)88:1<108::aid-cncr15>3.0.co;2-b ◽

2000 ◽

Vol 88 (1) ◽

pp. 108-113 ◽

Cited By ~ 49

Author(s):

Robert L. Camp ◽

Eric B. Rimm ◽

David L. Rimm

Keyword(s):

Lymph Node ◽

Breast Carcinoma ◽

Lymph Nodes ◽

Axillary Lymph Nodes ◽

Axillary Lymph ◽

Node Negative ◽

Poor Outcome

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Characterization of morphogenetic and invasive abilities of human mammary epithelial cells: Correlation with variations of urokinase-type plasminogen activator activity and type-1 plasminogen activator inhibitor level

Biology of the Cell ◽

10.1016/s0248-4900(97)89316-1 ◽

1997 ◽

Vol 89 (7) ◽

pp. 453-465 ◽

Cited By ~ 9

Author(s):

William Fauquette ◽

Xuefen Dong-Le Bourhis ◽

Albine Delannoy-Courdent ◽

Bénoni Boilly ◽

Xavier Desbiens

Keyword(s):

Plasminogen Activator ◽

Mammary Epithelial Cells ◽

Plasminogen Activator Inhibitor ◽

Mammary Epithelial ◽

Type Plasminogen Activator ◽

Urokinase Type Plasminogen Activator ◽

Inhibitor Level ◽

Human Mammary Epithelial

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Urokinase-Type Plasminogen Activator and Its Inhibitor Type 1 Predict Disease Outcome and Therapy Response in Primary Breast Cancer

Clinical Breast Cancer ◽

10.3816/cbc.2004.n.040 ◽

2004 ◽

Vol 5 (5) ◽

pp. 348-352 ◽

Cited By ~ 72

Author(s):

Nadia Harbeck ◽

Ronald E. Kates ◽

Manfred Schmitt ◽

Katja Gauger ◽

Marion Kiechle ◽

...

Keyword(s):

Breast Cancer ◽

Plasminogen Activator ◽

Primary Breast Cancer ◽

Therapy Response ◽

Disease Outcome ◽

Type Plasminogen Activator ◽

Urokinase Type Plasminogen Activator ◽

Inhibitor Type

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Elevated levels of urokinase-type plasminogen activator and plasminogen activator inhibitor type-1 in malignant human brain tumors

Fibrinolysis and Proteolysis ◽

10.1016/0268-9499(94)90453-7 ◽

1994 ◽

Vol 8 ◽

pp. 61 ◽

Cited By ~ 1

Author(s):

B. Landau ◽

S. Brern ◽

E. Verrusio ◽

H. Kwaan

Keyword(s):

Brain Tumors ◽

Human Brain ◽

Plasminogen Activator ◽

Plasminogen Activator Inhibitor ◽

Type Plasminogen Activator ◽

Urokinase Type Plasminogen Activator ◽

Inhibitor Type ◽

Activator Inhibitor Type ◽

Activator Inhibitor

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High Expression of Urokinase-Type Plasminogen Activator Is Associated with Lymph Node Metastasis of Invasive Ductal Carcinoma of the Breast

Journal of Breast Cancer ◽

10.4048/jbc.2016.19.2.156 ◽

2016 ◽

Vol 19 (2) ◽

pp. 156 ◽

Cited By ~ 6

Author(s):

Eun Young Kim ◽

Sung-Im Do ◽

Keehoon Hyun ◽

Yong Lai Park ◽

Dong-Hoon Kim ◽

...

Keyword(s):

Lymph Node ◽

Lymph Node Metastasis ◽

Plasminogen Activator ◽

Invasive Ductal Carcinoma ◽

Ductal Carcinoma ◽

High Expression ◽

Carcinoma Of The Breast ◽

Node Metastasis ◽

Type Plasminogen Activator ◽

Urokinase Type Plasminogen Activator

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92 Single chain urokinase-type plasminogen activator bound to its receptor is relatively resistant to plasminogen activator inhibitor type 1

Fibrinolysis and Proteolysis ◽

10.1016/s0268-9499(96)80179-2 ◽

1996 ◽

Vol 10 ◽

pp. 30

Keyword(s):

Plasminogen Activator ◽

Plasminogen Activator Inhibitor ◽

Single Chain ◽

Plasminogen Activator Inhibitor Type ◽

Type Plasminogen Activator ◽

Urokinase Type Plasminogen Activator ◽

Inhibitor Type ◽

Activator Inhibitor Type ◽

Activator Inhibitor

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