Noninflammatory breast carcinoma with skin involvement

Uwe Güth; Holger Moch; Linda Herberich; Wolfgang Holzgreve

doi:10.1002/cncr.11938

Breast carcinoma with noninflammatory skin involvement (T4b)

Cancer ◽

10.1002/cncr.21394 ◽

2005 ◽

Vol 104 (9) ◽

pp. 1862-1870 ◽

Cited By ~ 16

Author(s):

Uwe Guth ◽

Edward Wight ◽

Andreas Schotzau ◽

Igor Langer ◽

Holger Dieterich ◽

...

Keyword(s):

Breast Carcinoma ◽

Skin Involvement

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The Prognosis of Tumors with only Microscopic Skin Involvement without Clinical T4b Signs is Significantly Better than T4b Tumors in Breast Carcinoma

The Breast Journal ◽

10.1111/j.1524-4741.2010.01032.x ◽

2010 ◽

Vol 17 (1) ◽

pp. 47-55 ◽

Cited By ~ 6

Author(s):

Nüvit Duraker ◽

Bakır Batı ◽

Zeynep Civelek Çaynak ◽

Davut Demir ◽

İdris Kurtuluş

Keyword(s):

Breast Carcinoma ◽

Skin Involvement ◽

Better Than

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Breast carcinoma en Cuirasse - case report

Anais Brasileiros de Dermatologia ◽

10.1590/abd1806-4841.20131926 ◽

2013 ◽

Vol 88 (4) ◽

pp. 608-610 ◽

Cited By ~ 4

Author(s):

Gabriela Mantovanelli de Oliveira ◽

Daniele Bueno Carvalho Zachetti ◽

Hugo Rocha Barros ◽

Adriana Tiengo ◽

Ney Romiti

Keyword(s):

Breast Cancer ◽

Breast Carcinoma ◽

Cutaneous Metastasis ◽

Contralateral Breast ◽

Skin Involvement ◽

Breast Volume ◽

Invasive Ductal Breast Carcinoma ◽

Skin Infiltration ◽

One Year ◽

The Right

Cutaneous metastasis is a phenomenon that results from a tumor spreading via lymphatic or vascular embolization, direct implant during surgery or skin involvement by contiguity. The primary malignant tumor that most commonly metastasizes to the skin in women is breast cancer, which can be manifested through papulonodular lesions, erysipeloid or sclerodermiform infiltration, en cuirasse. We report the case of a female patient, 78 years old, with papular, scaly and confluent lesions in the right breast for one year, progressing to edema and skin infiltration, reduction of breast volume and plaque en cuirasse, and similar lesions in the contralateral breast and abdomen for four months. The pathological diagnosis was invasive ductal breast carcinoma with Paget-like foci, epidermal skin metastases and lymphatic embolization.

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Skin Involvement in Invasive Breast Carcinoma: Safety of Skin-Sparing Mastectomy

Annals of Surgical Oncology ◽

10.1245/aso.2003.05.001 ◽

2003 ◽

Vol 10 (2) ◽

pp. 102-107 ◽

Cited By ~ 69

Author(s):

Chiu M. Ho ◽

Colin K. L. Mak ◽

Yvonne Lau ◽

Wing Y. Cheung ◽

Miranda C. M. Chan ◽

...

Keyword(s):

Breast Carcinoma ◽

Invasive Breast Carcinoma ◽

Skin Involvement

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Immunostaining status of anaplastic lymphokinase in female breast cancer.

The Professional Medical Journal ◽

10.29309/tpmj/2020.27.08.4536 ◽

2020 ◽

Vol 27 (08) ◽

pp. 1777-1783

Author(s):

Syed Naqeeb Ali ◽

Syed Liaquat Ali ◽

Ghazala Panhwar ◽

Sarwat Batool ◽

Anila Qureshi ◽

...

Keyword(s):

Breast Cancer ◽

Lymph Node ◽

Breast Carcinoma ◽

Histological Grade ◽

Lymph Node Involvement ◽

Female Breast Cancer ◽

Skin Involvement ◽

Female Breast ◽

Node Involvement ◽

Relationship Of

Objectives: To determine the status of ALK immunostaining in female breast cancer and to find out the relationship of ALK expression with clinicopathological variables. Study Design: Cross Sectional study. Setting: Department of Pathology Al Tibri Medical College and Hospital Karachi and BMSI Jinnah Post Graduate Medical Centre, Karachi. Period: October 2016 to March 2017. Material & Methods: Total of 110 female cases with breast carcinoma by using non-probability purposive sampling technique. After taking informed consent from the patients, tissue samples were taken from received specimen of mastectomy for hematoxylin and eosin stain. The immunohistochemistry for ALK was assessed by using a DAKO monoclonal antibody using the paraffin embedded blocks of the diagnosed cases of breast carcinoma. Chi square test was used to find out the significance of differences among the variables. Results: Total of 110 cases with different histological classifications of breast cancer were observed i-e invasive ductal carcinoma 95(86%), invasive lobular carcinoma 9(8%), invasive medullary carcinoma 4(3.6%) and papillary carcinoma 2(1.8%). ALK expression was positive in 71(64%) and negative in 39 (35%) patients. Significant association was observed between ALK expression with histological grade (p=0.003), lymph node involvement (p=0.042) and skin involvement (p=0.025). Conclusion: Present study shows higher positive ALK expressions. Present study also indicates significant relationship of ALK with histological grade, lymph node involvement and skin involvement.

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