scholarly journals Enhanced MRI relaxivity of Gd3+-based contrast agents geometrically confined within porous nanoconstructs

2012 ◽  
Vol 7 (6) ◽  
pp. 501-508 ◽  
Author(s):  
Richa Sethi ◽  
Jeyarama S. Ananta ◽  
Christof Karmonik ◽  
Meng Zhong ◽  
Steve H. Fung ◽  
...  
Keyword(s):  
Contrast Agents ◽  
Enhanced Mri ◽  
Geometrically Confined

OPTIMAL DOSE OF MR CONTRAST AGENT IN T1-WEIGHTED MRI

2004 ◽  
Vol 16 (06) ◽  
pp. 331-336 ◽  
Author(s):  
C-C HSIAO ◽  
J-C JAO ◽  
Y-N TING ◽  
H-B PAN ◽  
P-C CHEN
Keyword(s):  
Contrast Agents ◽  
Pulse Sequences ◽  
Optimal Dose ◽  
Mri Contrast Agents ◽  
Lesion Detection ◽  
The Body ◽  
Rapid Expansion ◽  
Enhanced Mri ◽  
Contrast Enhanced ◽  
Contrast Enhanced Mri

Nowadays magnetic resonance imaging (MRI) has been commonly used in many indications. Concurrent development of MRI contrast agents has aided the rapid expansion and increased clinical efficacy. The use of contrast agents can improve lesion detection and characterization. With the contrast enhancement, lesion conspicuity is dramatically increased. Therefore, contrast enhanced MRI could provide more accurate diagnosis and be helpful for further therapy. The routinely used dose of contrast agents suggested by the documents only relies on the body weight of the subject. However, the relationship between the signal enhancement and the dose of contrast agents needs to be further investigated in order to achieve the maximum enhancement from optimal dose of the contrast agents. The aim of this study is to obtain the optimal dose of two contrast agents (Magnivist and Omniscan) for various T1-weighted pulse sequences (SE, SPGR, 2D TOF and 3D TOF) and various coils (body coil, NV array coil and head coil). The optimal dose is defined as achieving the MR images with the highest enhancement. The results show that there are significant differences in optimal dose among various pulse sequences. However, there are no significant differences in optimal dose among various coils and these two contrast agents. The advantage of finding optimal dose is to minimize dose and potential toxicity, and furthermore to decrease the cost of contrast agents. This study was done on a phantom, and it is expected to provide useful information to the contrast enhanced MRI in the routine clinical diagnosis and research in the future.

Dynamic contrast enhanced MRI of mouse fibrosarcoma using small-molecular and novel macromolecular contrast agents

2007 ◽  
Vol 23 (3-4) ◽  
pp. 85-90 ◽  
Author(s):  
Teodora Ivanuša ◽  
Katarina Beravs ◽  
Jure Medič ◽  
Igor Serša ◽  
Gregor Serša ◽  
...  
Keyword(s):  
Contrast Agents ◽  
Dynamic Contrast Enhanced Mri ◽  
Dynamic Contrast Enhanced ◽  
Enhanced Mri ◽  
Contrast Enhanced ◽  
Contrast Enhanced Mri

scholarly journals Quasi-Cubic Magnetite/Silica Core-Shell Nanoparticles as Enhanced MRI Contrast Agents for Cancer Imaging

PLoS ONE ◽  
2011 ◽  
Vol 6 (7) ◽  
pp. e21857 ◽  
Author(s):  
Jos L. Campbell ◽  
Jyoti Arora ◽  
Simon F. Cowell ◽  
Ashish Garg ◽  
Peter Eu ◽  
...  
Keyword(s):  
Contrast Agents ◽  
Cancer Imaging ◽  
Mri Contrast Agents ◽  
Core Shell ◽  
Shell Nanoparticles ◽  
Mri Contrast ◽  
Enhanced Mri ◽  
Silica Core ◽  
Core Shell Nanoparticles

Manganese-Enhanced MRI Contrast Agents: From Small Chelates to Nanosized Hybrids

2012 ◽  
Vol 2012 (12) ◽  
pp. 1987-2005 ◽  
Author(s):  
Marie Kueny-Stotz ◽  
Antonio Garofalo ◽  
Delphine Felder-Flesch
Keyword(s):  
Contrast Agents ◽  
Mri Contrast Agents ◽  
Mri Contrast ◽  
Enhanced Mri ◽  
Manganese Enhanced Mri

Gadoxetic acid-enhanced MRI in the detection of recurrent hepatocellular carcinoma in a patient with synchronous malignant tumors

2019 ◽  
pp. 50-56
Author(s):  
A. B. Lukianchenko ◽  
B. M. Medvedeva ◽  
K. A. Romanova ◽  
G. G. Karmazanovsky
Keyword(s):  
Hepatocellular Carcinoma ◽  
Case Report ◽  
Contrast Agents ◽  
Malignant Tumors ◽  
Gadoxetic Acid ◽  
Recurrent Hepatocellular Carcinoma ◽  
A Value ◽  
Enhanced Mri

The purpose of this case report is to present a value of gadoxetic acid¬enhanced MRI in the detection of an early recurrent hepatocellular carcinoma in a patient with synchronous multiple malignant tumors. The specific indications of using liver-specific contrast agents were introduced.

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