Synthesis and Evaluation of Voltage‐Gated Sodium Channel Blocking Pyrroline Derivatives Endowed with Both Antiarrhythmic and Antioxidant Activities

ChemMedChem ◽  
2020 ◽  
Author(s):  
Alessia Carocci ◽  
Mariagrazia Roselli ◽  
Roberta Budriesi ◽  
Matteo Micucci ◽  
Jean‐François Desaphy ◽  
...  
Keyword(s):  
Sodium Channel ◽  
Antioxidant Activities ◽  
Voltage Gated Sodium Channel ◽  
Voltage Gated ◽  
Channel Blocking

scholarly journals Discovery of Lacosamide Affinity Bait Agents That Exhibit Potent Voltage-Gated Sodium Channel Blocking Properties

2013 ◽  
Vol 4 (3) ◽  
pp. 463-474 ◽  
Author(s):  
Ki Duk Park ◽  
Xiao-Fang Yang ◽  
Hyosung Lee ◽  
Erik T. Dustrude ◽  
Yuying Wang ◽  
...  
Keyword(s):  
Sodium Channel ◽  
Voltage Gated Sodium Channel ◽  
Voltage Gated ◽  
Channel Blocking

The Voltage-Gated Sodium Channel Nav1.2 Contributes to Neurodegeneration in an Animal Model of Multiple Sclerosis

2016 ◽  
Vol 47 (S 01) ◽  
Author(s):  
W. Fazeli ◽  
B. Schattling ◽  
B. Engeland ◽  
M. Friese ◽  
D. Isbrand
Keyword(s):  
Multiple Sclerosis ◽  
Animal Model ◽  
Sodium Channel ◽  
Voltage Gated Sodium Channel ◽  
Voltage Gated

Homozygous SCN1B variants causing early infantile epileptic encephalopathy 52 affect voltage‐gated sodium channel function

Epilepsia ◽  
2021 ◽  
Author(s):  
Marcello Scala ◽  
Stephanie Efthymiou ◽  
Tipu Sultan ◽  
Jolien De Waele ◽  
Marta Panciroli ◽  
...  
Keyword(s):  
Sodium Channel ◽  
Epileptic Encephalopathy ◽  
Voltage Gated Sodium Channel ◽  
Voltage Gated ◽  
Channel Function

Neonatal Na V 1.5: Pharmacological distinctiveness of a cancer‐related voltage‐gated sodium channel splice variant

2021 ◽  
Author(s):  
Scott P. Fraser ◽  
Rustem Onkal ◽  
Margaux Theys ◽  
Frank Bosmans ◽  
Mustafa B. A. Djamgoz
Keyword(s):  
Sodium Channel ◽  
Splice Variant ◽  
Voltage Gated Sodium Channel ◽  
Voltage Gated
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