scholarly journals Gold Drugs with {Au(PPh 3 )} + Moiety: Advantages and Medicinal Applications

ChemMedChem ◽  
2020 ◽  
Vol 15 (22) ◽  
pp. 2136-2145
Author(s):  
Jenny R. Stenger‐Smith ◽  
Pradip K. Mascharak
Keyword(s):  
Gold Drugs

scholarly journals Polyhydroxyalkanoate/Antifungal Polyene Formulations with Monomeric Hydroxyalkanoic Acids for Improved Antifungal Efficiency

Antibiotics ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 737
Author(s):  
Marina Pekmezovic ◽  
Melina Kalagasidis Krusic ◽  
Ivana Malagurski ◽  
Jelena Milovanovic ◽  
Karolina Stępień ◽  
...  
Keyword(s):  
Fungal Growth ◽  
Pathogenic Fungi ◽  
Trichophyton Mentagrophytes ◽  
Microsporum Gypseum ◽  
Medium Chain Length ◽  
Gold Drugs ◽  
Growth Inhibitory Activity ◽  
Transdermal Application ◽  
Antifungal Efficiency

Novel biodegradable and biocompatible formulations of “old” but “gold” drugs such as nystatin (Nys) and amphotericin B (AmB) were made using a biopolymer as a matrix. Medium chain length polyhydroxyalkanoates (mcl-PHA) were used to formulate both polyenes (Nys and AmB) in the form of films (~50 µm). Thermal properties and stability of the materials were not significantly altered by the incorporation of polyenes in mcl-PHA, but polyene containing materials were more hydrophobic. These formulations were tested in vitro against a panel of pathogenic fungi and for antibiofilm properties. The films containing 0.1 to 2 weight % polyenes showed good activity and sustained polyene release for up to 4 days. A PHA monomer, namely 3-hydroxydecanoic acid (C10-OH), was added to the films to achieve an enhanced synergistic effect with polyenes against fungal growth. Mcl-PHA based polyene formulations showed excellent growth inhibitory activity against both Candida yeasts (C. albicans ATCC 1023, C. albicans SC5314 (ATCC MYA-2876), C. parapsilosis ATCC 22019) and filamentous fungi (Aspergillus fumigatus ATCC 13073; Trichophyton mentagrophytes ATCC 9533, Microsporum gypseum ATCC 24102). All antifungal PHA film preparations prevented the formation of a C. albicans biofilm, while they were not efficient in eradication of mature biofilms, rendering them suitable for the transdermal application or as coatings of implants.

INDIA'S COAST REGION - THE EASIEST ROUTE FOR CONDUCTING ILLEGAL ACTIVITIES - AN UNDERSTANDING

2021 ◽  
Vol 1 (9) ◽  
pp. 235-239
Author(s):  
Sumanta Bhattacharya ◽  
Jayanta Ray ◽  
Shakti Sinha ◽  
Bhavneet Kaur Sachdev
Keyword(s):  
Drug Trafficking ◽  
Terrorist Attack ◽  
Western Coast ◽  
Illegal Fishing ◽  
Gold Drugs ◽  
Long Time ◽  
Illegal Activities ◽  
The Government ◽  
Coast Region ◽  
Mumbai Port

Indian sea route are an easy target for smuggling and conducting of anti-national activities. Mumbai port which is the largest port in India has been a place for terrorism activities since a long time, the 26/attack which is regarded as the deadliest terrorist attack, India has ever experience, the terrorist had enter India through sea port , since 1960s the business of smuggling of gold , drugs and other luxury items is going on between Dubai to Mumbai to Gujarat . Smuggling of items like fuel, textile happening through different states. Illegal fishing is also very common, In fact after the lockdown, many states have brought in new rules and regulation in their fisheries culture /sector, even the government has introduced schemes and is investing a lot . There are many agencies and ministries at the local, state and center to coordinate among different committees and stakeholders and increase the manpower. The eastern and the western coast share their water border with several countries which support criminal activities in the region. Most of the illegal migrant enter India and leave India through these ports for instances cases of Bangladesh and Sri Lanka. India needs to strengthen its coastal security across the country. Keywords: Coastal security, sea roots, smuggling, drug trafficking, fisheries sector, 26/11 attack

Mechanism of action of the gold drugs in arthritis

1993 ◽  
Vol 51 (1-2) ◽  
pp. 418
Author(s):  
J. Reglinski ◽  
W.E. Smith
Keyword(s):  
Mechanism Of Action ◽  
Gold Drugs

scholarly journals China’s ancient gold drugs

Gold Bulletin ◽  
2001 ◽  
Vol 34 (1) ◽  
pp. 24-29 ◽  
Author(s):  
Zhao Huaizhi ◽  
Ning Yuantao
Keyword(s):  
Gold Drugs

ChemInform Abstract: GOLD-197 MOESSBAUER STUDIES OF SOME GOLD(I) THIOLATES AND THEIR PHOSPHINE COMPLEXES INCLUDING CERTAIN ANTIARTHRITIC GOLD DRUGS

1984 ◽  
Vol 15 (1) ◽  
Author(s):  
D. T. HILL ◽  
B. M. SUTTON ◽  
A. A. ISAB ◽  
T. RAZI ◽  
P. J. SADLER ◽  
...  
Keyword(s):  
Phosphine Complexes ◽  
Gold Drugs

Gold-197 Moessbauer studies of some gold(I) thiolates and their phosphine complexes including certain antiarthritic gold drugs

1983 ◽  
Vol 22 (20) ◽  
pp. 2936-2942 ◽  
Author(s):  
David T. Hill ◽  
Blaine M. Sutton ◽  
Anvar A. Isab ◽  
M. Tahir Razi ◽  
Peter J. Sadler ◽  
...  
Keyword(s):  
Phosphine Complexes ◽  
Gold Drugs

Gold Drugs

2016 ◽  
Author(s):  
M. W. G. De Bolster
Keyword(s):  
Gold Drugs
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