Synthesis of Trifluoromethyl-α,β-unsaturated Lactones and Pyrazolinones and Discovery of Influenza Virus Polymerase Inhibitors

ChemMedChem ◽  
2018 ◽  
Vol 13 (22) ◽  
pp. 2390-2399 ◽  
Author(s):  
Satoshi Mizuta ◽  
Juliann Nzembi Makau ◽  
Ayako Kitagawa ◽  
Kanami Kitamura ◽  
Hiroki Otaki ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Polymerase Inhibitors ◽  
Unsaturated Lactones

scholarly journals Front Cover: Synthesis of Trifluoromethyl-α,β-unsaturated Lactones and Pyrazolinones and Discovery of Influenza Virus Polymerase Inhibitors (ChemMedChem 22/2018)

ChemMedChem ◽  
2018 ◽  
Vol 13 (22) ◽  
pp. 2349-2349
Author(s):  
Satoshi Mizuta ◽  
Juliann Nzembi Makau ◽  
Ayako Kitagawa ◽  
Kanami Kitamura ◽  
Hiroki Otaki ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Front Cover ◽  
Polymerase Inhibitors ◽  
Unsaturated Lactones

Lead Optimization of Influenza Virus RNA Polymerase Inhibitors Targeting PA–PB1 Interaction

2021 ◽  
Author(s):  
Satoshi Mizuta ◽  
Hiroki Otaki ◽  
Takeshi Ishikawa ◽  
Juliann Nzembi Makau ◽  
Tomoko Yamaguchi ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Rna Polymerase ◽  
Lead Optimization ◽  
Polymerase Inhibitors ◽  
Virus Rna

Prediction and characterization of influenza virus polymerase inhibitors through blind docking and ligand based virtual screening

2021 ◽  
Vol 321 ◽  
pp. 114784
Author(s):  
Horacio Pérez-Sánchez ◽  
D. Thirumal Kumar ◽  
C. George Priya Doss ◽  
Ricardo Rodríguez-Schmidt ◽  
José Pedro Cerón-Carrasco ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Virtual Screening ◽  
Polymerase Inhibitors
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