scholarly journals Gram‐Positive and Gram‐Negative Antibiotic Activity of Asymmetric and Monomeric Robenidine Analogues

ChemMedChem ◽  
2018 ◽  
Vol 13 (23) ◽  
pp. 2573-2580 ◽  
Author(s):  
Cecilia C. Russell ◽  
Andrew Stevens ◽  
Hongfei Pi ◽  
Manouchehr Khazandi ◽  
Abiodun D. Ogunniyi ◽  
...  
Keyword(s):  
Antibiotic Activity ◽  
Gram Positive ◽  
Gram Negative

AN ANTIBIOTIC-PRODUCING BACTERIUM OF THE GENUS PSEUDOMONAS

1954 ◽  
Vol 1 (2) ◽  
pp. 118-124 ◽  
Author(s):  
S. H. F. Chinn
Keyword(s):  
Pure Culture ◽  
Fusarium Culmorum ◽  
Antibiotic Activity ◽  
In Vitro Studies ◽  
Gram Positive ◽  
Gram Negative ◽  
Helminthosporium Sativum ◽  
Pathogenic Organisms

A Gram-negative rod, conforming; to Pseudomonas viscosa (Frankland and Frankland) Migula, was isolated in practically pure culture from a sample of wheat that did not show the usual mixture of epiphytes. In vitro studies revealed an unusual antibiotic spectrum against a variety of Gram-positive and -negative bacteria as well as against Helminthosporium sativum and Fusarium culmorum. Comparative.studies of the organism and P. aeruginosa, P. fluorescens, and P. chlororaphis indicated that it possessed greater antibiotic activity than any of these three species of Pseudomonas. Application to the control of some plant pathogenic organisms is suggested.

scholarly journals Antibiotic Activity of Actinobacteria from the Digestive Tract of Millipede Nedyopus dawydoffiae (Diplopoda)

Antibiotics ◽  
2018 ◽  
Vol 7 (4) ◽  
pp. 94 ◽  
Author(s):  
Alla Glukhova ◽  
Anna Karabanova ◽  
Andrey Yakushev ◽  
Irina Semenyuk ◽  
Yuliya Boykova ◽  
...  
Keyword(s):  
Digestive Tract ◽  
Antibiotic Production ◽  
Antimicrobial Properties ◽  
Antimicrobial Activities ◽  
Antibiotic Activity ◽  
Rrna Gene ◽  
Gram Positive ◽  
Genus Streptomyces ◽  
Gram Negative ◽  
Different Strains

Because of the spread of drug resistance, it is necessary to look for new antibiotics that are effective against pathogenic microorganisms. The purpose of this study was to analyse the species composition of actinobacteria isolated from the digestive tract of the millipedes Nedyopus dawydoffiae and to determine their antimicrobial properties. Species identification was carried out on the basis of the morphological and culture properties and the sequence of the 16S rRNA gene. Actinobacteria were grown in different liquid media. Antibiotic properties were determined against some Gram-positive and Gram-negative bacteria as well as fungi. Of the 15 isolated strains, 13 have antibiotic activity against Gram-positive bacteria (including methicillin-resistant Staphylococcus aureus—MRSA) and fungi, but there was no antibiotic activity against Gram-negative test strains Escherichia coli ATCC 25922 and Pseudomonas aeruginosa ATCC 27853. It was established that antibiotic-producing actinobacteria belong to eight species of the genus Streptomyces. Depending on the nutrient medium, actinobacteria demonstrate different antimicrobial activities. As an example, S. hydrogenans shows that even strains selected in one population differ by the range of antimicrobial activity and the level of biosynthesis. Since the antibiotic production is considered as a feature for species competition in the microbiota community, the variability of antibiotic production among different strains of the same species is an adaptive characteristic for the competition in millipedes’ digestive tract community.

scholarly journals Effect of N-acetylcysteine on antibiotic activity and bacterial growth in vitro

1977 ◽  
Vol 5 (1) ◽  
pp. 58-61 ◽  
Author(s):  
M F Parry ◽  
H C Neu
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Bacterial Growth ◽  
Antibiotic Activity ◽  
Clinical Use ◽  
Microbiology Laboratory ◽  
Gram Positive ◽  
Gram Negative ◽  
Gram Positive Bacteria

The antibiotic bacerial inactivity of N-acetylcysteine (NAC) and its interaction with penicillin and aminocyclitol antibiotics was evaluated. NAC inhibited growth of both gram-negative and gram-positive bacteria. Strains of Pseudomonas aeruginosa were more susceptible than other microorgainsms tested. P. aeruginosa strains were inhibited synergistically by NAC and carbenicillin or ticarcillin. However, NAC antagonized the activity of gentamicin and tobramycin. These findings have implications for the combined clinical use of NAC and aerosolized antibiotics and are also important for the processing of sputum specimens in the microbiology laboratory.

Potentiation of antibiotic activity by chalcone (E)-1-(4′-aminophenyl)-3-(furan-2-yl)-prop-2-en-1-one against gram-positive and gram-negative MDR strains

2020 ◽  
Vol 148 ◽  
pp. 104453 ◽  
Author(s):  
Carlos A.N. Ferraz ◽  
Saulo R. Tintino ◽  
Alexandre M.R. Teixeira ◽  
Paulo N. Bandeira ◽  
Hélcio S. Santos ◽  
...  
Keyword(s):  
Antibiotic Activity ◽  
Gram Positive ◽  
Gram Negative

The Classic: Streptomycin, a Substance Exhibiting Antibiotic Activity against Gram-Positive and Gram-Negative Bacteria

2005 ◽  
Vol &NA; (437) ◽  
pp. 3-6 ◽  
Author(s):  
Albert Schatz ◽  
Elizabeth Bugie ◽  
Selman A Waksman ◽  
Arlen D Hanssen ◽  
Robin Patel ◽  
...  
Keyword(s):  
Antibiotic Activity ◽  
Gram Negative Bacteria ◽  
Gram Positive ◽  
Gram Negative

PRODUCTION OF CLAVIFORMIN BY SOIL PENICILLIA

1946 ◽  
Vol 24e (1) ◽  
pp. 1-9 ◽  
Author(s):  
A. G. Lochhead ◽  
F. E. Chase ◽  
G. B. Landerkin
Keyword(s):  
Active Substance ◽  
Antibiotic Activity ◽  
Gram Negative Bacteria ◽  
Gram Positive ◽  
Gram Negative ◽  
Culture Filtrates

Of various strains of fungi isolated from soil that showed antibiotic activity against Gram-positive and Gram-negative bacteria, two species of Penicillium, producing culture filtrates of high antibacterial titre, were studied in more detail. The active substance, when crystallized, was considered to be claviformin (clavacin, clavatin, patulin). Studies on the production of the antibiotic, its assay, and its extraction from culture filtrates are described.

scholarly journals A Novel Polycationic Analogue of Gratisin with Antibiotic Activity against both Gram-positive and Gram-negative Bacteria

2008 ◽  
Vol 61 (1) ◽  
pp. 33-35 ◽  
Author(s):  
Makoto Tamaki ◽  
Manabu Kokuno ◽  
Yumiko Suzuki ◽  
Mitsuko Iwama ◽  
Mitsuno Shindo ◽  
...  
Keyword(s):  
Antibiotic Activity ◽  
Gram Negative Bacteria ◽  
Gram Positive ◽  
Gram Negative
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