scholarly journals Cytotoxic Activity and Structure-Activity Relationship of Triazole-Containing Bis(Aryl Ether) Macrocycles

ChemMedChem ◽  
2018 ◽  
Vol 13 (12) ◽  
pp. 1193-1209 ◽  
Author(s):  
Eduardo Hernández-Vázquez ◽  
Alejandra Chávez-Riveros ◽  
Adriana Romo-Pérez ◽  
María Teresa Ramírez-Apán ◽  
Alma D. Chávez-Blanco ◽  
...  
2008 ◽  
Vol 61 (7) ◽  
pp. 531 ◽  
Author(s):  
Qiang Zhou ◽  
Jing Hou ◽  
Huamin Li ◽  
Li Cui ◽  
Han Jia ◽  
...  

Designed as a new series of molecules that contain the quinoline substructure, several 11H-indolo[3.2-c]quinoline derivatives were synthesized and subjected to biological evaluation. Several compounds were found to exhibit cytotoxic activity against the growth of colon (HTC-8), liver (BEL-7402), gastric (BCG-823), pulmonary gland (A549), and ovary (A2780) cancer cell lines. The structure–activity relationship of these compounds is discussed.


2001 ◽  
Vol 64 (10) ◽  
pp. 1318-1321 ◽  
Author(s):  
Liliana Betancur-Galvis ◽  
Carmen Zuluaga ◽  
Manuel Arnó ◽  
Miguel A. González ◽  
Ramón J. Zaragozá

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
MA Brenzan ◽  
CV Nakamura ◽  
BPD Filho ◽  
T Ueda-Nakamura ◽  
MCM Young ◽  
...  

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