scholarly journals The Cell Surface Receptor CD44: NMR-Based Characterization of Putative Ligands

ChemMedChem ◽  
2016 ◽  
Vol 11 (10) ◽  
pp. 1097-1106 ◽  
Author(s):  
Carlo Baggio ◽  
Elisa Barile ◽  
Gianluigi Di Sorbo ◽  
Thomas J. Kipps ◽  
Maurizio Pellecchia
Keyword(s):  
Cell Surface ◽  
Cell Surface Receptor ◽  
Surface Receptor

scholarly journals Isolation of an adhesion-mediating protein from chick neural retina adherons.

1985 ◽  
Vol 101 (3) ◽  
pp. 1071-1077 ◽  
Author(s):  
D Schubert ◽  
M LaCorbiere
Keyword(s):  
Cell Surface ◽  
Heparan Sulfate ◽  
Cultured Cells ◽  
Cell Types ◽  
Neural Retina ◽  
Cell Surface Receptor ◽  
Isolation And Characterization ◽  
Surface Receptor ◽  
Adhesive Interactions

Adherons are high molecular weight glycoprotein complexes which are released into the growth medium of cultured cells. They mediate the adhesive interactions of many cell types, including those of embryonic chick neural retina. The cell surface receptor for chick neural retina adherons has been purified, and shown to be a heparan sulfate proteoglycan (Schubert, D., and M. LaCorbiere, 1985, J. Cell Biol., 100:56-63). This paper describes the isolation and characterization of a protein in neural retina adherons which interacts specifically with the cell surface receptor. The 20,000-mol-wt protein, called retinal purpurin (RP), stimulates neural retina cell-substratum adhesion and prolongs the survival of neural retina cells in culture. The RP protein interacts with heparin and heparan sulfate, but not with other glycosaminoglycans. Monovalent antibodies against RP inhibit RP-cell adhesion as well as adheron-cell interactions. The RP protein is found in neural retina, but not in other tissues such as brain and muscle. These data suggest that RP plays a role in both the survival and adhesive interactions of neural retina cells.

Characterization of the Strongylocentrotus Purpuratus Egg Cell Surface Receptor for Sperm

1986 ◽  
pp. 293-313 ◽  
Author(s):  
Norka Ruiz-Bravo ◽  
Daniel P. Rossignol ◽  
Glenn L. Decker ◽  
Lawrence I. Rosenberg ◽  
William J. Lennarz
Keyword(s):  
Cell Surface ◽  
Strongylocentrotus Purpuratus ◽  
Cell Surface Receptor ◽  
Egg Cell ◽  
Surface Receptor

Development and Characterization of a High-Throughput System for Assessing Cell-Surface Receptor−Ligand Engagement

Langmuir ◽  
2005 ◽  
Vol 21 (18) ◽  
pp. 8374-8384 ◽  
Author(s):  
G. M. Harbers ◽  
L. J. Gamble ◽  
E. F. Irwin ◽  
D. G. Castner ◽  
K. E. Healy
Keyword(s):  
Cell Surface ◽  
High Throughput ◽  
Cell Surface Receptor ◽  
Receptor Ligand ◽  
Surface Receptor
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