Frontiers in Medicinal Chemistry 2015: Meet the Experts of MedChem near the Cradle of Medicinal and Pharmaceutical Chemistry

ChemMedChem ◽  
2015 ◽  
Vol 10 (7) ◽  
pp. 1267-1271
Author(s):  
Christof Wegscheid-Gerlach ◽  
Hans-Dieter Gerber ◽  
Wibke E. Diederich
Keyword(s):  
Medicinal Chemistry ◽  
Pharmaceutical Chemistry

A Mini Review on Recent Advancements in the Therapeutic Potentials of Benzothiazoles

2019 ◽  
Vol 16 ◽  
Author(s):  
Rubina Bhutani ◽  
Garima Kapoor ◽  
Dharam Pal Pathak ◽  
Asif Husain ◽  
Ravi Kant ◽  
...  
Keyword(s):  
Medicinal Chemistry ◽  
Therapeutic Potential ◽  
Pharmaceutical Chemistry ◽  
Biological Potential ◽  
Heterocyclic Derivatives ◽  
Anti Inflammatory ◽  
Clinical Drugs

: Among the various fused heterocyclic rings, benzothiazole and its analogues have been explored broadly in search of newer therapeutic medicinal agents. The benzothiazole scaffold has been associated with huge biological potential like anticancer, antidiabetic, anti-inflammatory, anti-tubercular, antiviral, anti-convulsant etc. The occurrence of benzothiazole core in various compounds proves its value in the sphere of pharmaceutical chemistry. The connected research and developments in benzothiazole based chemistry become an active topic for medicinal scientists. A large number of benzothiazole and its heterocyclic derivatives are available in the market and used for the treatment of as clinical drugs have been extensively used in practice to treat diverse types of ailments with high therapeutic potential. This review presents the latest therapeutic developments of benzothiazole containing compounds in the medicinal chemistry.

Bicyclic 6 + 6 Systems: Advances in the Chemistry of Heterocyclic Compounds Incorporated Pyrimido[1,2-a]Pyrimidine Skeleton

2020 ◽  
Vol 17 (6) ◽  
pp. 717-739 ◽  
Author(s):  
Mohamed Monier ◽  
Doaa Abdel-Latif ◽  
Ahmed El-Mekabaty ◽  
Khaled M. Elattar
Keyword(s):  
Heterocyclic Compounds ◽  
Medicinal Chemistry ◽  
Present Review ◽  
Pharmaceutical Chemistry ◽  
Significant Variable ◽  
Biological Applications ◽  
Carbon And Nitrogen ◽  
Biological Compounds ◽  
Synthetic Routes

The present review has highlighted the chemistry of pyrimido[1,2-a]pyrimidine compounds as one of the most important classes of heterocyclic systems. The main sections include: (1) The synthesis of pyrimido[1,2-a]pyrimidines, (2) reactivity of the substituents attached to the carbon and nitrogen atoms of the ring and (3) biological applications. A discussion demonstrated that the proposed mechanisms of unexpected synthetic routes were intended. The purpose of this review is to provide an overview of the chemistry of pyrimido[1,2-a]pyrimidines to date, in which the compounds should be widely applied in medicinal and pharmaceutical chemistry based on the significant, variable and potent biological results of pyrimidopyrimidine and pyridopyrimidine analogs. This survey will assist scientists in the organic and medicinal chemistry fields to design and develop procedures for the construction of new standard biological compounds.

New Research on the Pharmaceutical Chemistry of Plant Polysaccharides

2013 ◽  
Vol 411-414 ◽  
pp. 3237-3241
Author(s):  
Qi Chang Dai ◽  
Cui Ting Chen ◽  
Miao Yu ◽  
Yu Bin Ji
Keyword(s):  
Medicinal Chemistry ◽  
Chemical Technology ◽  
Pharmaceutical Chemistry ◽  
Separation And Purification ◽  
Plant Polysaccharides ◽  
Advantages And Disadvantages ◽  
Extraction Separation ◽  
New Research

The researches on plant polysaccharides develop rapidly in recent years. In this paper, the studies of pharmaceutical chemistry of polysaccharides from plants are reviewed. We introduce researches’ new progresses and results of the extraction, separation and purification in the field of pharmaceutical chemistry and expound the advantages and disadvantages of the applications of physical techniques, chemical technology and biotechnology. The applications of statistic principles in the field of medicinal chemistry are also discussed in this article.

scholarly journals CHEMICAL AND PHARMACOLOGICAL EVOLUTION OF SOME SYNTHESIZED CHALCONES AND HETROCYCLIC COMPOUNDS

2021 ◽  
Vol 9 (07) ◽  
pp. 747-771
Author(s):  
Geeta N Lodhi ◽  
Amit Nayak
Keyword(s):  
Medicinal Chemistry ◽  
Pharmaceutical Chemistry ◽  
Hydroxyl Group ◽  
Pharmaceutical Drugs ◽  
Open Chain ◽  
Blue Green Algae ◽  
Slime Moulds ◽  
Generic Term ◽  
Quality Aspects ◽  
Anti Fungal

Pharmaceutical chemistry is focused on quality aspects of medicines and aims to assure fitness for the purpose of medicinal products. With centuries medicinal chemistry had emerged as a magnanimous field of science getting a facelift from the available natural compounds for synthesis of newer and complex molecules possessing medicinal activity while the transit from the earth to a synthetically furnished laboratory. Medicinal chemistry or pharmaceutical chemistry is a discipline at the intersection of chemistry and pharmacology involved with designing, synthesizing and developing pharmaceutical drugs. Chalconesis a generic term given to compounds bearing the 1,3-diarylprop2-en-1-one, which can be functionlized in the propane chain by the presence of olefinic, keto and/or hydroxyl group. Chalcones belongs to the flavonoid family. Chemically chalcones consisted of open chain flavonoids in which the two aromaticrings are joined by a three carbon a,ß-unsaturated carbonyl system (Dhar, 1981). Microorganisms are a heterogeneous group of several distinct classes of living beings. They were classified under third kingdom, theProstita. Based on differences in cellular organization and biochemistry, the kingdom prostita has been divided into two groups, Prokaryotes and Eukaryotes. Bacteria and blue green algae are prokaryotes while fungi, other algae, slime moulds and protozoa are eukaryotes. Anti-fungal drugs are among the most frequently prescribed preparations because of their fungal activity. They are widely used for the treatment of the fungal diseases such as Candidiasis and Apergillosis. These agents prevent from fungal infection. Anti-oxidant drugs are among the most frequently prescribed preparations prevent Oxidation.

scholarly journals 29th Annual GP2A Medicinal Chemistry Conference

2021 ◽  
Vol 14 (12) ◽  
pp. 1278
Author(s):  
Jean-Jacques Helesbeux ◽  
Laura Carro ◽  
Florence O. McCarthy ◽  
Vânia M. Moreira ◽  
Francesca Giuntini ◽  
...  
Keyword(s):  
Medicinal Chemistry ◽  
Cutting Edge ◽  
Pharmaceutical Chemistry ◽  
Young Researcher ◽  
High Level

The 29th Annual GP2A (Group for the Promotion of Pharmaceutical chemistry in Academia) Conference was a virtual event this year due to the COVID-19 pandemic and spanned three days from Wednesday 25 to Friday 27 August 2021. The meeting brought together an international delegation of researchers with interests in medicinal chemistry and interfacing disciplines. Abstracts of keynote lectures given by the 10 invited speakers, along with those of the 8 young researcher talks and the 50 flash presentation posters, are included in this report. Like previous editions, the conference was a real success, with high-level scientific discussions on cutting-edge advances in the fields of pharmaceutical chemistry.

scholarly journals CHEMICAL AND PHARMACOLOGICAL EVOLUTION OF SOME SYNTHESIZED CHALCONES AND HETROCYCLIC COMPOUNDS

2021 ◽  
Vol 9 (07) ◽  
pp. 772-795
Author(s):  
Geeta N. Lodhi ◽  
Amit Nayak
Keyword(s):  
Medicinal Chemistry ◽  
Pharmaceutical Chemistry ◽  
Hydroxyl Group ◽  
Pharmaceutical Drugs ◽  
Open Chain ◽  
Blue Green Algae ◽  
Slime Moulds ◽  
Generic Term ◽  
Quality Aspects ◽  
Anti Fungal

Pharmaceutical chemistry is focused on quality aspects of medicines and aims to assure fitness for the purpose of medicinal products. With centuries medicinal chemistry had emerged as a magnanimous field of science getting a facelift from the available natural compounds for synthesis of newer and complex molecules possessing medicinal activity while the transit from the earth to a synthetically furnished laboratory. Medicinal chemistry or pharmaceutical chemistry is a discipline at the intersection of chemistry and pharmacology involved with designing, synthesizing and developing pharmaceutical drugs. Chalconesis a generic term given to compounds bearing the 1,3-diarylprop2-en-1-one, which can be functionlized in the propane chain by the presence of olefinic, keto and/or hydroxyl group. Chalcones belongs to the flavonoid family. Chemically chalcones consisted of open chain flavonoids in which the two aromaticrings are joined by a three carbon a,ß-unsaturated carbonyl system (Dhar, 1981). Microorganisms are a heterogeneous group of several distinct classes of living beings. They were classified under third kingdom, theProstita. Based on differences in cellular organization and biochemistry, the kingdom prostita has been divided into two groups, Prokaryotes and Eukaryotes. Bacteria and blue green algae are prokaryotes while fungi, other algae, slime moulds and protozoa are eukaryotes. Anti-fungal drugs are among the most frequently prescribed preparations because of their fungal activity. They are widely used for the treatment of the fungal diseases such as Candidiasis and Apergillosis. These agents prevent from fungal infection. Anti-oxidant drugs are among the most frequently prescribed preparations prevent Oxidation.

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