A Chimeric SERM-Histone Deacetylase Inhibitor Approach to Breast Cancer Therapy

Hitisha K. Patel; Marton I. Siklos; Hazem Abdelkarim; Emma L. Mendonca; Aditya Vaidya; Pavel A. Petukhov; Gregory R. J. Thatcher

doi:10.1002/cmdc.201300270

A Chimeric SERM-Histone Deacetylase Inhibitor Approach to Breast Cancer Therapy

ChemMedChem ◽

10.1002/cmdc.201300270 ◽

2013 ◽

Vol 9 (3) ◽

pp. 602-613 ◽

Cited By ~ 15

Author(s):

Hitisha K. Patel ◽

Marton I. Siklos ◽

Hazem Abdelkarim ◽

Emma L. Mendonca ◽

Aditya Vaidya ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Therapy ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Breast Cancer Therapy ◽

Deacetylase Inhibitor

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Cover Picture: A Chimeric SERM-Histone Deacetylase Inhibitor Approach to Breast Cancer Therapy (ChemMedChem 3/2014)

ChemMedChem ◽

10.1002/cmdc.201490005 ◽

2014 ◽

Vol 9 (3) ◽

pp. 413-413

Author(s):

Hitisha K. Patel ◽

Marton I. Siklos ◽

Hazem Abdelkarim ◽

Emma L. Mendonca ◽

Aditya Vaidya ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Therapy ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Breast Cancer Therapy ◽

Deacetylase Inhibitor

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Development of a Novel Ferrocenyl Histone Deacetylase Inhibitor for Triple-Negative Breast Cancer Therapy

Organometallics ◽

10.1021/acs.organomet.8b00354 ◽

2018 ◽

Vol 37 (14) ◽

pp. 2368-2375 ◽

Cited By ~ 5

Author(s):

Chu Tang ◽

Yang Du ◽

Qian Liang ◽

Zhen Cheng ◽

Jie Tian

Keyword(s):

Breast Cancer ◽

Cancer Therapy ◽

Histone Deacetylase ◽

Triple Negative Breast Cancer ◽

Histone Deacetylase Inhibitor ◽

Triple Negative ◽

Breast Cancer Therapy ◽

Deacetylase Inhibitor

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Histone deacetylase inhibitor suberoyl bis-hydroxamic acid suppresses cell proliferation and induces apoptosis in breast cancer cells

Molecular Medicine Reports ◽

10.3892/mmr.2014.3076 ◽

2014 ◽

Vol 11 (4) ◽

pp. 2908-2912 ◽

Cited By ~ 3

Author(s):

XINMIAO YANG ◽

NING ZHANG ◽

ZELIANG SHI ◽

ZHANGYU YANG ◽

XICHUN HU

Keyword(s):

Breast Cancer ◽

Cell Proliferation ◽

Cancer Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Hydroxamic Acid ◽

Breast Cancer Cells ◽

Deacetylase Inhibitor

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The histone deacetylase inhibitor trichostatin A alters microRNA expression profiles in apoptosis-resistant breast cancer cells

Oncology Reports ◽

10.3892/or.2011.1488 ◽

2011 ◽

Cited By ~ 4

Author(s):

Bridgette Collins-Burow

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Breast Cancer Cells ◽

Trichostatin A ◽

Expression Profiles ◽

Microrna Expression ◽

Deacetylase Inhibitor ◽

Histone Deacetylase Inhibitor Trichostatin

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Phase I-II study of the histone deacetylase inhibitor (HDACi) vorinostat plus paclitaxel and bevacizumab in metastatic breast cancer (MBC): New York Cancer Consortium trial P7703.

10.1158/0008-5472.sabcs-404 ◽

2009 ◽

Cited By ~ 4

Author(s):

B Ramaswamy ◽

K Bhalla ◽

B Cohen ◽

C Pellegrino ◽

D Hershman ◽

...

Keyword(s):

Breast Cancer ◽

New York ◽

Metastatic Breast Cancer ◽

Phase I ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Metastatic Breast ◽

Deacetylase Inhibitor

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A Phase II Study of the Histone Deacetylase Inhibitor, Vorinostat, in Combination with Trastuzumab in Patients with Advanced Metastatic and/or Local Chest Wall Recurrent HER-2 Amplified Breast Cancer Resistant to Transtuzumab-Containing Therapy: (E1104) a Trial of the Eastern Cooperative Oncology Group.

10.1158/0008-5472.sabcs-09-5084 ◽

2009 ◽

Cited By ~ 7

Author(s):

R. Swaby ◽

M. Wang ◽

J. Sparano ◽

K. Bhalla ◽

N. Meropol ◽

...

Keyword(s):

Breast Cancer ◽

Histone Deacetylase ◽

Chest Wall ◽

Phase Ii ◽

Histone Deacetylase Inhibitor ◽

Phase Ii Study ◽

Eastern Cooperative Oncology Group ◽

Oncology Group ◽

Deacetylase Inhibitor ◽

Her 2

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Abstract P1-07-01: Histone deacetylase inhibitor entinostat reverses epithelial to mesenchymal transition of breast cancer cells by reversing the repression of E-cadherin

10.1158/0008-5472.sabcs13-p1-07-01 ◽

2013 ◽

Author(s):

GJ Sabnis ◽

P Shah ◽

A Kazi ◽

Y Gau ◽

S Chumsri ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Breast Cancer Cells ◽

Epithelial To Mesenchymal Transition ◽

Mesenchymal Transition ◽

Deacetylase Inhibitor ◽

E Cadherin

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Abstract P6-12-14: Histone deacetylase inhibitor suberoylanilide hydroxamic acid targets breast cancer stem cells and inhibits metastasis

10.1158/0008-5472.sabcs13-p6-12-14 ◽

2013 ◽

Author(s):

K Chu ◽

TL Green ◽

KM Boley ◽

M Cristofanilli ◽

FM Robertson

Keyword(s):

Breast Cancer ◽

Stem Cells ◽

Cancer Stem Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Hydroxamic Acid ◽

Suberoylanilide Hydroxamic Acid ◽

Breast Cancer Stem Cells ◽

Deacetylase Inhibitor

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Abstract 5847: A histone deacetylase inhibitor OBP-801 and eribulin synergistically inhibit the growth with apoptosis in triple-negative breast cancer cells

10.1158/1538-7445.am2018-5847 ◽

2018 ◽

Author(s):

Hisako Ono ◽

Yoshihiro Sowa ◽

Yosuke Iizumi ◽

Mano Horinaka ◽

Tetsuya Taguchi ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Triple Negative Breast Cancer ◽

Histone Deacetylase Inhibitor ◽

Breast Cancer Cells ◽

Triple Negative ◽

Deacetylase Inhibitor

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Synergistic epigenetic reactivation of estrogen receptor-alpha (ERalpha) by combined green tea polyphenol and histone deacetylase inhibitor in ERalpha-negative breast cancer cells

Molecular Cancer ◽

10.1186/1476-4598-9-274 ◽

2010 ◽

Vol 9 (1) ◽

pp. 274 ◽

Cited By ~ 115

Author(s):

Yuanyuan Li ◽

Yih-Ying Yuan ◽

Syed M. Meeran ◽

Trygve O. Tollefsbol

Keyword(s):

Breast Cancer ◽

Estrogen Receptor ◽

Histone Deacetylase ◽

Green Tea ◽

Histone Deacetylase Inhibitor ◽

Breast Cancer Cells ◽

Estrogen Receptor Alpha ◽

Tea Polyphenol ◽

Deacetylase Inhibitor ◽

Green Tea Polyphenol

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