scholarly journals Characteristics, mechanism, and management of pain in atopic dermatitis: A literature review

2021 ◽  
Vol 11 (10) ◽  
Author(s):  
Jia‐Xin Li ◽  
Rui‐Jia Dong ◽  
Yue‐Ping Zeng
Keyword(s):  
Atopic Dermatitis ◽  
Literature Review

scholarly journals What Do We Know about Pruritus in Very Young Infants? A Literature Review

Cells ◽  
2021 ◽  
Vol 10 (10) ◽  
pp. 2788
Author(s):  
Camille Le Pors ◽  
Matthieu Talagas ◽  
Claire Abasq-Thomas ◽  
Séverine Henry ◽  
Laurent Misery ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Literature Review ◽  
Adverse Effects ◽  
Negative Impact ◽  
Vulnerable Population ◽  
Google Scholar ◽  
Skin Development ◽  
Young Infants ◽  
Chronic Pruritus

In infants, pruritus is frequently considered as absent because they do not scratch themselves. Because pruritus could induce severe adverse effects in this vulnerable population, we aimed to review existing evidence on the ability of young infants to experience itch and on how to assess itch-related discomfort in this population. A literature review was performed (Pubmed, Google Scholar). Neurological itch pathways are well described. Skin development starts early during gestation. At 34 weeks of gestation, skin is almost complete while skin adaptations occur after birth. Newborn skin is neurologically functional, including the ability for young infants to feel pain. Similarities and interactions between pain and pruritus support the hypothesis that infants could feel pruritus. However, the existence of pruritus in infants has never been evidenced. Many itchy conditions can affect them, suggesting non-negligible prevalence of infant pruritus among which atopic dermatitis (AD) is the most studied disease. Studies reported a negative impact of AD on children and their families. There is no existing validated method to assess pruritus in infants, although they may feel pruritus and chronic pruritus can lead to serious adverse effects. To appropriately diagnose pruritus appears of great interest among young infants. Development of a method is required to this aim.

scholarly journals MicroRNA Cross-Involvement in Autism Spectrum Disorders and Atopic Dermatitis: A Literature Review

2019 ◽  
Vol 8 (1) ◽  
pp. 88 ◽  
Author(s):  
Alessandro Tonacci ◽  
Gianluca Bagnato ◽  
Gianluca Pandolfo ◽  
Lucia Billeci ◽  
Francesco Sansone ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Literature Review ◽  
Small Molecules ◽  
Autism Spectrum ◽  
Clinical Perspective ◽  
Contributing Factors ◽  
Gene Environment ◽  
Mrna Transcripts ◽  
Spectrum Disorders ◽  
Common Pathogenesis

Autism Spectrum Disorder (ASD) is a category of neurodevelopmental disturbances seriously affecting social skills, to which the scientific community has paid great attention in last decades. To date, their pathogenesis is still unknown, but several studies highlighted the relevance of gene-environment interactions in the onset of ASD. In addition, an immune involvement was seen in a wide number of ASD subjects, leading several researchers to hypothesize a possible common pathogenesis between ASD and immune disturbances, including Atopic Dermatitis (AD). In general, among potential contributing factors, microRNAs (miRNAs), small molecules capable of controlling gene expression and targeting mRNA transcripts, might represent one of the major circulating link, possibly unraveling the connections between neurodevelopmental and immune conditions. Under such premises, we conducted a systematic literature review, under the PRISMA guidelines, trying to define the panel of common miRNAs involved in both ASD and AD. The review retrieved articles published between January 1, 2005, and December 13, 2018, in PubMed, ScienceDirect, PsycARTICLES, and Google Scholar. We found a handful of works dealing with miRNAs in ASD and AD, with the most overlapping dysregulated miRNAs being miR-146 and miR-155. Two possible compounds are abnormally regulated in both ASD and AD subjects, possibly cross-contributing to the interactions between the two disorders, setting the basis to investigate more precisely the possible link between ASD and AD from another, not just clinical, perspective.

scholarly journals Correction to: Crisaborole Ointment, 2%, for Treatment of Patients with Mild-to-Moderate Atopic Dermatitis: Systematic Literature Review and Network Meta-Analysis

2020 ◽  
Vol 10 (6) ◽  
pp. 1441-1444
Author(s):  
Kyle Fahrbach ◽  
Jialu Tarpey ◽  
Evelien Bergrath Washington ◽  
Rachel Hughes ◽  
Howard Thom ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Literature Review ◽  
Systematic Literature Review ◽  
Meta Analysis

scholarly journals Crisaborole Ointment, 2%, for Treatment of Patients with Mild-to-Moderate Atopic Dermatitis: Systematic Literature Review and Network Meta-Analysis

2020 ◽  
Vol 10 (4) ◽  
pp. 681-694 ◽  
Author(s):  
Kyle Fahrbach ◽  
Jialu Tarpey ◽  
Evelien Bergrath Washington ◽  
Rachel Hughes ◽  
Howard Thom ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Literature Review ◽  
Systematic Literature Review ◽  
Meta Analysis

scholarly journals A Literature Review for Developing the Clinical Phenotype Evaluation System of Atopic Dermatitis

2016 ◽  
Vol 29 (1) ◽  
pp. 145-156 ◽  
Author(s):  
Jin-Hyang Ahn ◽  
Young-Hee Yun ◽  
Kyu-Seok Kim ◽  
Bo-Hyeong Jang ◽  
Seong-Gyu Ko ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Literature Review ◽  
Evaluation System ◽  
Clinical Phenotype
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