scholarly journals Worldwide surveys on anaphylaxis to sublingual immunotherapy with house dust mite tablets are urgently needed

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ralph Mösges ◽  
Desiderio Passali ◽  
Mario Di Gioacchino
2017 ◽  
Vol 66 (1) ◽  
pp. 89-96 ◽  
Author(s):  
Kenjiro Shima ◽  
Toshiyuki Koya ◽  
Keisuke Tsukioka ◽  
Takuro Sakagami ◽  
Takashi Hasegawa ◽  
...  

2010 ◽  
Vol 75 (1) ◽  
pp. 19-26
Author(s):  
Lidija Burazer ◽  
Katarina Milovanovic ◽  
Tanja Cirkovic-Velickovic ◽  
Marija Gavrovic-Jankulovic

Allergen-specific immunotherapy with house dust mite (HDM) allergen extracts can effectively alleviate the symptoms of allergic rhinitis and asthma. The efficacy of the immunotherapeutic treatment is highly dependent on the quality of house dust mite vaccines. This study was performed to assess the stability of house dust mite allergen vaccines prepared for sublingual immunotherapy. Lyophilized Dermatophagoides pteronyssinus (Dpt) mite bodies were the starting material for the production of sublingual vaccines in four therapeutic concentrations. The stability of the extract for vaccine production, which was stored below 4 ?C for one month, showed consistence in the protein profile in SDS PAGE. ELISA-inhibition showed that the potencies of Dpt vaccines during a 12 month period were to 65-80 % preserved at all analyzed therapeutic concentrations. This study showed that glycerinated Dpt vaccines stored at 4?C preserved their IgE-binding potential during a 12 month period, implying their suitability for sublingual immunotherapeutic treatment of HDM allergy.


2019 ◽  
Vol 42 (6) ◽  
pp. 1030-1033 ◽  
Author(s):  
Hirokazu Kito ◽  
Weibin Du ◽  
Hiroshi Nakazawa ◽  
Kaare Lund ◽  
Katsuyo Ohashi-Doi

Allergy ◽  
2019 ◽  
Vol 74 (4) ◽  
pp. 780-787 ◽  
Author(s):  
Marta Ponce ◽  
Fabian Schroeder ◽  
Christina Bannert ◽  
Klara Schmidthaler ◽  
Christian Skjødt Hansen ◽  
...  

2015 ◽  
Vol 135 (6) ◽  
pp. 1494-1501.e6 ◽  
Author(s):  
Hendrik Nolte ◽  
Jennifer Maloney ◽  
Harold S. Nelson ◽  
David I. Bernstein ◽  
Susan Lu ◽  
...  

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