scholarly journals Amiodarone in restoration and maintenance of sinus rhythm in patients with chronic atrial fibrillation after unsuccessful direct-current cardioversion

1997 ◽  
Vol 20 (4) ◽  
pp. 337-340 ◽  
Author(s):  
Grzegorz Opolski ◽  
Jolanta Stanislawska ◽  
Aleksander Górecki ◽  
Grazyna Świěcicka ◽  
Tadeusz Kraska ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Sinus Rhythm ◽  
Direct Current ◽  
Chronic Atrial Fibrillation ◽  
Direct Current Cardioversion

scholarly journals Comparison of QT dispersion during atrial fibrillation and sinus rhythm in the same patients, at normal and prolonged ventricular repolarization

EP Europace ◽  
2000 ◽  
Vol 2 (1) ◽  
pp. 20-31 ◽  
Author(s):  
B. Houltz ◽  
B. Darpö ◽  
K. Swedberg ◽  
P. Blomström ◽  
H.J.G.M. Crijns ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Sinus Rhythm ◽  
Direct Current ◽  
Chronic Atrial Fibrillation ◽  
Qt Dispersion ◽  
Ventricular Repolarization ◽  
Drug Induced ◽  
Rr Interval ◽  
Direct Current Cardioversion ◽  
Increased Risk

Abstract Aims Drug-induced increase in QT dispersion has been associated with increased risk of ventricular proarrhythmia. The aim of the present study was to compare QT dispersion during atrial fibrillation and sinus rhythm in the same patients at normal and prolonged ventricular repolarization. Methods and Results Sixty-one patients who had had chronic atrial fibrillation for 8±14 months received a 6 h infusion of the Ikr-blocker almokalant, the first 90 min of which are used for this analysis. The following day, after conversion to sinus rhythm, by almokalant (n=19) or direct current cardioversion (n=42), an identical 90 min infusion was administered. Prior to infusion, there was no difference in precordial QT dispersion between atrial fibrillation and sinus rhythm (29±12 vs 36±17 ms, P=ns). During infusion, at prolonged repolarization, the increase in QT dispersion was greater during sinus rhythm than during atrial fibrillation (58±49 vs 30±15 ms,P =0·0011, after 30 min infusion). No correlation was found between QT dispersion and the QT or RR interval. Conclusion QT dispersion during atrial fibrillation does not differ from QT dispersion during sinus rhythm during normal repolarization, while measurement of QT dispersion during prolonged repolarization, induced by an Ikr-blocker, yielded larger values during sinus rhythm than during atrial fibrillation.

Usefulness of the Atrial Emptying Fraction to Predict Maintenance of Sinus Rhythm After Direct Current Cardioversion for Atrial Fibrillation

2016 ◽  
Vol 118 (9) ◽  
pp. 1345-1349 ◽  
Author(s):  
Christina L. Luong ◽  
Darby J.S. Thompson ◽  
Kenneth G. Gin ◽  
John Jue ◽  
Parvathy Nair ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Sinus Rhythm ◽  
Direct Current ◽  
Direct Current Cardioversion

scholarly journals Investigating the efficacy of chest pressure for direct current cardioversion in atrial fibrillation: a randomised control trial protocol (Pressure-AF)

Open Heart ◽  
2021 ◽  
Vol 8 (2) ◽  
pp. e001739
Author(s):  
David Ferreira ◽  
Philo Mikhail ◽  
Michael McGee ◽  
Andrew Boyle ◽  
Aaron Sverdlov ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Sinus Rhythm ◽  
Direct Current ◽  
Intervention Group ◽  
Randomised Clinical Trial ◽  
Randomised Control Trial ◽  
Control Group ◽  
Double Blind ◽  
Transthoracic Impedance ◽  
Direct Current Cardioversion

IntroductionAtrial fibrillation (AF) is the most common sustained arrhythmia worldwide. Direct current cardioversion is commonly used to restore sinus rhythm in patients with AF. Chest pressure may improve cardioversion success through decreasing transthoracic impedance and increasing cardiac energy delivery. We aim to assess the efficacy and safety of routine chest pressure with direct current cardioversion for AF.Methods and analysisMulticentre, double blind (patient and outcome assessment), randomised clinical trial based in New South Wales, Australia. Patients will be randomised 1:1 to control and interventional arms. The control group will receive four sequential biphasic shocks of 150 J, 200 J, 360 J and 360 J with chest pressure on the last shock, until cardioversion success. The intervention group will receive the same shocks with chest pressure from the first defibrillation. Pads will be placed in an anteroposterior position. Success of cardioversion will be defined as sinus rhythm at 1 min after shock. The primary outcome will be total energy provided. Secondary outcomes will be success of first shock to achieve cardioversion, transthoracic impedance and sinus rhythm at post cardioversion ECG.Ethics and disseminationEthics approval has been confirmed at all participating sites via the Research Ethics Governance Information System. The trial has been registered on the Australia New Zealand Clinical Trials Registry (ACTRN12620001028998). De-identified patient level data will be available to reputable researchers who provide sound analysis proposals.

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