Electrocardiogram signal variance analysis in the diagnosis of coronary artery disease-A comparison with exercise stress test in an angiographically documented high prevalence population

1993 ◽  
Vol 16 (9) ◽  
pp. 671-682 ◽  
Author(s):  
Jacek Nowak ◽  
Marco Yléan ◽  
Inger Hagerman ◽  
Olof Nyquist ◽  
Christer Sylven
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Stress Test ◽  
Exercise Stress Test ◽  
Variance Analysis ◽  
Exercise Stress ◽  
High Prevalence ◽  
Electrocardiogram Signal ◽  
Artery Disease

Hemodynamic Characteristics of Patients with Coronary Artery Disease Presenting False-Negative Exercise Stress Test

Angiology ◽  
1992 ◽  
Vol 43 (6) ◽  
pp. 506-511 ◽  
Author(s):  
Michihito Sekiya ◽  
Makoto Suzuki ◽  
Yasushi Fujiwara ◽  
Takumi Sumimoto ◽  
Mareomi Hamada ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Stress Test ◽  
False Negative ◽  
Exercise Stress Test ◽  
Exercise Stress ◽  
Hemodynamic Characteristics ◽  
Artery Disease

Recent advances in the role of the adenosinergic system in coronary artery disease

2020 ◽  
Author(s):  
Franck Paganelli ◽  
Marine Gaudry ◽  
Jean Ruf ◽  
Régis Guieu
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Stress Test ◽  
Exercise Stress Test ◽  
Tissue Hypoxia ◽  
Exercise Stress ◽  
Fractional Flow ◽  
Coronary Syndrome ◽  
Flow Reserve ◽  
Artery Disease

Abstract Adenosine is an endogenous nucleoside that plays a major role in the physiology and physiopathology of the coronary artery system, mainly by activating its A2A receptors (A2AR). Adenosine is released by myocardial, endothelial, and immune cells during hypoxia, ischaemia, or inflammation, each condition being present in coronary artery disease (CAD). While activation of A2AR improves coronary blood circulation and leads to anti-inflammatory effects, down-regulation of A2AR has many deleterious effects during CAD. A decrease in the level and/or activity of A2AR leads to: (i) lack of vasodilation, which decreases blood flow, leading to a decrease in myocardial oxygenation and tissue hypoxia; (ii) an increase in the immune response, favouring inflammation; and (iii) platelet aggregation, which therefore participates, in part, in the formation of a fibrin-platelet thrombus after the rupture or erosion of the plaque, leading to the occurrence of acute coronary syndrome. Inflammation contributes to the development of atherosclerosis, leading to myocardial ischaemia, which in turn leads to tissue hypoxia. Therefore, a vicious circle is created that maintains and aggravates CAD. In some cases, studying the adenosinergic profile can help assess the severity of CAD. In fact, inducible ischaemia in CAD patients, as assessed by exercise stress test or fractional flow reserve, is associated with the presence of a reserve of A2AR called spare receptors. The purpose of this review is to present emerging experimental evidence supporting the existence of this adaptive adenosinergic response to ischaemia or inflammation in CAD. We believe that we have achieved a breakthrough in the understanding and modelling of spare A2AR, based upon a new concept allowing for a new and non-invasive CAD management.

Prognostic Value of Exercise Stress Test and Dobutamine Stress Echo in Patients with Known Coronary Artery Disease

2009 ◽  
Vol 26 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Francesca Innocenti ◽  
Francesca Caldi ◽  
Irene Tassinari ◽  
Chiara Agresti ◽  
Costanza Burgisser ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Prognostic Value ◽  
Stress Test ◽  
Exercise Stress Test ◽  
Dobutamine Stress ◽  
Exercise Stress ◽  
Stress Echo ◽  
Artery Disease

Variance ecg detection of coronary artery disease-a comparison with exercise stress test and myocardial scintigraphy

1994 ◽  
Vol 17 (3) ◽  
pp. 132-140 ◽  
Author(s):  
Christer SylvÉN ◽  
Inger Hagerman ◽  
Marco YiÉN ◽  
Olof Nyquist ◽  
Jacek Nowak
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Stress Test ◽  
Exercise Stress Test ◽  
Myocardial Scintigraphy ◽  
Exercise Stress ◽  
Artery Disease
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