Myocardial infarction and the weather: A significant positive correlation between the onset of heart infarct and 28 KHz atmospherics-A pilot study

1985 ◽  
Vol 8 (3) ◽  
pp. 149-151 ◽  
Author(s):  
H. Baumer ◽  
G. Ruhenstroth-Bauer ◽  
E. M. Burkel ◽  
W. Sönning ◽  
B. Filipiak
Keyword(s):  
Myocardial Infarction ◽  
Pilot Study ◽  
Significant Positive Correlation ◽  
Positive Correlation ◽  
Heart Infarct

Influence of Emotional Content and Perceived Relevance on Spread of Urban Legends: A Pilot Study

2008 ◽  
Vol 102 (2) ◽  
pp. 623-629 ◽  
Author(s):  
Ellen M. Cotter
Keyword(s):  
Pilot Study ◽  
Significant Positive Correlation ◽  
Emotional Content ◽  
Strongly Correlated ◽  
Local Component ◽  
Positive Correlation ◽  
Urban Legends ◽  
Perceived Relevance ◽  
Local Connection

This study examined factors thought to be associated with the spread of urban legends. 62 participants (84% female, 65% white, M age = 22 yr.) read 15 urban legends, 3 of which had a stated local component, and rated various characteristics of each legend, including how scary it was, how believable it was, and how likely the participants would be to tell it to someone else. As predicted, both a high fear rating and a high believability rating were positively correlated with the reported intent to tell (p60 = .41, p<.0001 and p60 = .67, p<.02, respectively). There was also a significant positive correlation between familiarity and intent to tell (p60 = .22, p< .0001); however, presence of a local connection was not strongly correlated with intent to tell. It is possible that the local stories were less believable because they all involved ghosts.

scholarly journals Serum complement (C3, C4) levels in patients with acute myocardial infarction and angina pectoris

2008 ◽  
Vol 33 (3) ◽  
pp. 98-102 ◽  
Author(s):  
ASM Giasuddin ◽  
Jamila M ElMahdawi ◽  
Fakhri M ElHassadi
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Angina Pectoris ◽  
Acute Phase ◽  
Significant Positive Correlation ◽  
Complement C3 ◽  
Serum Complement ◽  
Positive Correlation ◽  
Control Subjects

Serum complement (C3, C4) levels in Libyan patients with acute myocardial infarction (AMI; 31 patients) and angina pectoris (AP; 11 patients) at the 1st day and 7th day of attack were estimated. A group of 26 healthy Libyans were taken as control subjects (CS). Serum C3 and C4 levels (mean ± SD, mg/dl) were elevated at the 1st day in AMI as well as AP patients (C3 → AMI1: 154.0 ± 28.5, AP1: 152.0 ± 45.0, CS: 132.0 ± 8.0, ANOVA: p=0.0072; C4→ AMI1: 38 ± 13, AP1: 37 ± 17, CS: 29 ± 6, ANOVA: p=0.0160). No significant differences for the elevated C3 and C4 levels at the 1st day were observed between the two diseases groups (AMI1 vs AP1 → C3: p=0.879, C4: p=0.818). At the 7th day, C3 and C4 levels were further elevated in AMI, while they remained at the similar elevated levels in AP (C3 → AMI 7: 173.1 ± 28.0, AP 7: 149.0 ± 41.0, CS: 132.0 ± 8.0, ANOVA: p=0.0000; C4 → AMI 7: 46.0 ± 7.0, AP 7: 36.0 ± 15.0, CS: 29.0 ± 6.0, ANOVA: p=0.0000). Again, no significance differences for the raised C3 and C4 levels at the 7th day was observed between AMI and AP patients (AMI 7 vs AP 7 → C3: P=0.059, C4: p=0.06). The C3 elevation showed significant positive correlation in AMI group (r=0.522, p=0.003) while it was insignificant in AP patients (r=0.037, p=0.915). Regarding C4 levels, it was significantly correlated in AMI (r=0.483, p=0.006), and in AP, although it was positively correlated (r=0.656, P=0.028) the observed difference was not significant (t=0.29, p=0.778). In conclusion, serum C3 and C4 levels were more profoundly elevated in AMI compared to AP patients suggestive of an acute phase and inflammatory response.DOI = 10.3329/bmrcb.v33i3.1141Bangladesh Med Res Counc Bull 2007; 33: 98-102

scholarly journals Translation, cultural adaptation and validation of the Italian version of the Brief Index of Lupus Damage: the BILDit

Lupus ◽  
2020 ◽  
Vol 29 (10) ◽  
pp. 1198-1205
Author(s):  
Elena Elefante ◽  
Chiara Tani ◽  
Adele Santoni ◽  
Valentina Lorenzoni ◽  
Chiara Stagnaro ◽  
...  
Keyword(s):  
Pilot Study ◽  
Lupus Erythematosus ◽  
Cultural Adaptation ◽  
Significant Positive Correlation ◽  
Damage Index ◽  
Organ Damage ◽  
Systemic Lupus ◽  
Italian Version ◽  
Positive Correlation ◽  
Self Evaluation

Objectives The Brief Index of Lupus Damage (BILD) is an instrument of self-evaluation of organ damage for systemic lupus erythematosus (SLE) patients. The objectives of this study were the translation, cultural adaptation and validation of the Italian version of the BILD (BILDit). Methods The process of translation and cultural adaptation followed published guidelines. The BILDit was pretested in a pilot study with 30 SLE patients in order to evaluate acceptability, reliability, comprehension and feasibility, and then validated in consecutive SLE patients attending our clinic. Results A total of 167 SLE patients were enrolled. In the pilot study, the BILDit demonstrated good acceptability, feasibility and comprehensibility and a very high degree of reliability (Cronbach’s α = 1). In the validation cohort, the BILDit showed a significant positive correlation with the Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index (SDI; ρ = 0.69; p < 0.001). Analysing the item-by-item correlation between the BILDit and the SDI, a good correlation ( p < 0.001) was found for 73.1% of the items. In the multivariate analysis, the BILDit showed a significant positive correlation with age and disease duration ( p < 0.01). Conclusions The BILDit seems to be an acceptable and reliable instrument for patient self-evaluation of disease damage, with a good correlation with the SDI. It can be considered as a screening tool for the evaluation of organ damage starting from the patient’s perceptive.

scholarly journals Oxidative stress in myocardial infarction-does it correlate with the cardiac marker troponin?

2021 ◽  
Vol 8 (3) ◽  
pp. 190-192
Author(s):  
Pallavi R ◽  
Prabha S P ◽  
Sumina Cherian ◽  
Venugopal K ◽  
Geetha A
Keyword(s):  
Oxidative Stress ◽  
Myocardial Infarction ◽  
Heart Attack ◽  
Significant Positive Correlation ◽  
Troponin I ◽  
Healthy Controls ◽  
Healthy Individuals ◽  
Cardiac Marker ◽  
Positive Correlation ◽  
Significant Difference

A myocardial infarction (MI), often known as a heart attack, occurs when blood supply to a region of the heart is reduced or stopped, resulting in heart muscle damage. One of the elemental mechanisms responsible for the development of myocardial infarction is oxidative stress. The study aims to assess the Oxidative stress and Troponin I levels in patients with myocardial infarction (MI) and compare them with the level of these parameters in healthy controls. An attempt has been made to find if there is any correlation between oxidative stress and Troponin I levels in patients with myocardial infarction.The Cardiac marker Troponin I and the marker of oxidative stress malondialdehyde were estimated in 30 patients with myocardial infarction and 30 healthy individuals who acted as controls. A statistically significant difference was observed between Troponin I and MDA in patients with MI as compared with controls. A significant positive correlation was also observed between MDA and Troponin I levels. In our study there wasa significant positive correlation between oxidative stress and Troponin I. Further studies with a larger number of subjects will be needed to find if oxidative stress plays a role in the pathogenesis of myocardial infarction.

scholarly journals Myocardial Infarction as An Independent Predictor of Intramyocardial Hemorrhage in Acute Reperfused Myocardial Ischemic Rats

2021 ◽  
Author(s):  
Rui Xia ◽  
Tong Zhu ◽  
Yu Zhang ◽  
Bo He ◽  
Yushu Chen ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Significant Positive Correlation ◽  
T2 Mapping ◽  
Critical Factor ◽  
Myocardial Edema ◽  
Myocardial Tissue ◽  
Experimental Sample ◽  
Positive Correlation ◽  
Infarction Size ◽  
Custom Made

Abstract Background: In the previous studies, hemorrhage occurred only with the largest infarctions and studies confirmed a moderate correlation between the extent of necrosis and hemorrhage, but the extent of infarction size of these studies was limited. This study was to find the correlations between intramyocardial hemorrhage (IMH), myocardial infarction (MI), and myocardial edema (ME) from days 2 to 7 in a 7.0T MR scanner.Methods: The different degrees of myocardial ischemia were induced by occluding different sections of the proximal left anterior descending coronary artery (1–3 mm under the left auricle). T2*-mapping, T2-mapping and late gadolinium enhancement (LGE) sequences were performed on a 7.0T MR system at day 2 and 7. T2*- and T2-maps were calculated using a custom-made software. All areas were expressed as a percentage of the whole myocardial tissue of the left ventricle. The rats were divided into two groups based on the T2* results; MI with IMH was referred to as the +IMH group, while MI without IMH was referred to as the –IMH group.Results: The final experimental sample consisted of 25 rats in the +IMH group and 10 rats in the –IMH group. For the +IMH group. On day 2, There was a significant positive correlation between IMH size and MI size (r = 0.677, P<0.01), and a positive correlation between IMH size and ME size (r = 0.552, P<0.01). On day 7, There was a significant positive correlation between IMH size and MI size (r = 0.711, P<0.01), while no correlation was found between IMH size and ME size (r = 0.429, P = 0.097). Conclusions: Infarction size prior to reperfusion is a critical factor in determining whether a MI is hemorrhagic or non-hemorrhagic in rats.

Self-Esteem, Anxiety, and Drug Use

1992 ◽  
Vol 71 (3) ◽  
pp. 896-898 ◽  
Author(s):  
Douglas N. Taylor ◽  
Jose Del Pilar
Keyword(s):  
Pilot Study ◽  
Drug Use ◽  
Trait Anxiety ◽  
Negative Correlation ◽  
Significant Positive Correlation ◽  
Significant Negative Correlation ◽  
Self Esteem ◽  
Positive Correlation ◽  
Nonclinical Sample ◽  
The Relationship

This pilot study evaluated the relationship between self-esteem, anxiety, and drug use in a nonclinical sample of 30 men, ages 16 to 43 years, who completed and returned inventories on self-esteem, trait anxiety, and drug use which they had received by mail. Analysis showed a significant negative correlation between self-esteem and drug use and a significant positive correlation between trait anxiety and drug use. Also, a significant negative correlation was found between self-esteem and trait anxiety. Implications are discussed.

scholarly journals Alterations of serum high sensitive C reactive protein and lipid levels in newly diagnosed myocardial infarction subjects

2019 ◽  
Vol 7 (12) ◽  
pp. 4682
Author(s):  
R. R. Aparna ◽  
D. Raja Rajeswari ◽  
K. Ramalingam ◽  
R. Viswa Kumar ◽  
D. Balakrishna
Keyword(s):  
Myocardial Infarction ◽  
Significant Positive Correlation ◽  
Ldl Cholesterol ◽  
Hdl Cholesterol ◽  
P Value ◽  
Newly Diagnosed ◽  
Lipid Levels ◽  
Positive Correlation ◽  
Hs Crp ◽  
Inflammatory Component

Background: Acute Myocardial Infarction (AMI) is one of the major causes of mortality in the world. Atherosclerosis leading to AMI is the most common and severe clinical manifestation observed. Dyslipidemia is one of main traditional risk factor for MI, but in more than 50% of CHD events dyslipidemia was absent.  Atherosclerosis is considered as both a chronic inflammatory condition and a disorder of lipid metabolism. The present study was aimed to estimate the levels of serum lipids (total cholesterol, LDL cholesterol, HDL cholesterol) and hs-CRP an inflammatory marker in newly diagnosed AMI cases and to find out any correlation between these two.Methods: The study was conducted on 50 newly diagnosed myocardial infarction cases, admitted in Cardiology Department Narayana Medical College, Nellore. Both the sexes were included. Fifty age and sex matched healthy individuals were selected as controls. Lipid levels are estimated by end point colorimetric assay (HUMANSTAR kit) and hs-CRP was estimated by immunofluorescence technique (Boditechkit).Results: Significant raised levels of hs-CRP (p value <0.0001) and low HDL cholesterol (p value =0.0085) levels among the cases was noticed. A significant positive correlation was observed between LDL cholesterol and hsCRP (r=0.109, p=0.040). A non-significant positive correlation between hsCRP and HDL cholesterol  (r=0.291, p=0.453) was observed.Conclusions: The results of the study implicate the role of inflammatory component in causing atherosclerosis or coronary artery disease rather than dyslipidaemias alone to be attributed for atherogenesis. Concomitantly HDL cholesterol levels were found to be low in cases that results from the inflammatory component in atherogenesis.

scholarly journals Correlates of SARS-CoV-2 Variants on Deaths, Case Incidence and Case Fatality Ratio among the Continents for the Period of 1 December 2020 to 15 March 2021

Genes ◽  
2021 ◽  
Vol 12 (7) ◽  
pp. 1061
Author(s):  
Wajdy J. Al-Awaida ◽  
Baker Jawabrah Al Hourani ◽  
Samer Swedan ◽  
Refat Nimer ◽  
Foad Alzoughool ◽  
...  
Keyword(s):  
Negative Correlation ◽  
Significant Positive Correlation ◽  
Vaccine Development ◽  
Case Fatality ◽  
Significant Negative Correlation ◽  
Reference Sequence ◽  
Genome Sequences ◽  
Positive Correlation ◽  
Case Fatality Ratio ◽  
Epidemiological Surveys

The outbreak of coronavirus disease 2019 (COVID-19), by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has quickly developed into a worldwide pandemic. Mutations in the SARS-CoV-2 genome may affect various aspects of the disease including fatality ratio. In this study, 553,518 SARS-CoV-2 genome sequences isolated from patients from continents for the period 1 December 2020 to 15 March 2021 were comprehensively analyzed and a total of 82 mutations were identified concerning the reference sequence. In addition, associations between the mutations and the case fatality ratio (CFR), cases per million and deaths per million, were examined. The mutations having the highest frequencies among different continents were Spike_D614G and NSP12_P323L. Among the identified mutations, NSP2_T153M, NSP14_I42V and Spike_L18F mutations showed a positive correlation to CFR. While the NSP13_Y541C, NSP3_T73I and NSP3_Q180H mutations demonstrated a negative correlation to CFR. The Spike_D614G and NSP12_P323L mutations showed a positive correlation to deaths per million. The NSP3_T1198K, NS8_L84S and NSP12_A97V mutations showed a significant negative correlation to deaths per million. The NSP12_P323L and Spike_D614G mutations showed a positive correlation to the number of cases per million. In contrast, NS8_L84S and NSP12_A97V mutations showed a negative correlation to the number of cases per million. In addition, among the identified clades, none showed a significant correlation to CFR. The G, GR, GV, S clades showed a significant positive correlation to deaths per million. The GR and S clades showed a positive correlation to number of cases per million. The clades having the highest frequencies among continents were G, followed by GH and GR. These findings should be taken into consideration during epidemiological surveys of the virus and vaccine development.

scholarly journals Comparative Evaluation of Adenoids, Upper Airway, and Tongue Using “Predictors of Difficult Airways” in Class II Division 1 and Division 2 Cases with Class I Cases: Prospective In Vivo Observational Study

2021 ◽  
pp. 030157422096341
Author(s):  
Smita Mangesh Choudhari ◽  
Sunita Shrivastav
Keyword(s):  
Significant Positive Correlation ◽  
Upper Airway ◽  
Class Ii ◽  
Class I ◽  
Positive Correlation ◽  
Division 1 ◽  
Difficult Airways ◽  
Mandibular Protrusion ◽  
Division 2 ◽  
Class Ii Division 1

Introduction: Altered nasorespiratory function leads to altered craniofacial growth. Thus, airway evaluation is important for preventive, interceptive, and corrective orthodontic treatment. The aim of this study was to evaluate and compare adenoids, the upper airway, the tongue, and mandibular dimensions using “predictors of difficult airways” in class II division 1 and class II division 2 cases with class I cases. Method: Sixty subjects of age 15 to 18 years were divided into 3 groups (group 1: class I cases; group 2: class II division 1 cases; and group 3: class II division 2 cases) based on cephalometric parameters, with 20 cases in each group. Cephalometric evaluation of adenoids and the nasopharyngeal airway was done using the Handelman–Osborne area method. Upper and lower airway evaluation was done using McNamara’s linear method. “Predictors of difficult airways” were used for evaluation of the airway, which included nasal competency, the Mallampati scale, mandibular length, mandibular protrusion, and the thyromental distance. Results: The present study found a significant positive correlation between the grades of nasal competency and percentage adenoid wall area, and a significant negative correlation between the grades of nasal competency and the upper airway. There was a significant positive correlation between the grades of nasal competency and mandibular length, and a significant positive correlation between the grades of mandibular protrusion and mandibular length. There was a significant positive correlation between the grades of the thyromental distance and mandibular length. Conclusion: It was concluded that the “predictors of difficult airways” would be helpful in early diagnosis and identification of potential risk factors that may cause “breathing disorders”–related malocclusions and later on increase the risk of developing OSA.

Sedative effects of alfaxalone and hydromorphone with or without midazolam in cats: a pilot study

2021 ◽  
pp. 1098612X2199615
Author(s):  
Emily P Wheeler ◽  
Amanda L Abelson ◽  
Jane C Lindsey ◽  
Lois A Wetmore
Keyword(s):  
Pilot Study ◽  
Significant Positive Correlation ◽  
Time Correlation ◽  
Catheter Placement ◽  
Blinded Study ◽  
Sedative Effects ◽  
Sedation Scores ◽  
Adult Cats ◽  
To Receive

Objectives The aim of this pilot study was to compare the quality of sedation and ease of intravenous (IV) catheter placement following sedation using two intramuscular (IM) sedation protocols in cats: hydromorphone, alfaxalone and midazolam vs hydromorphone and alfaxalone. Methods This was a prospective, randomized and blinded study. Cats were randomly assigned to receive an IM injection of hydromorphone (0.1 mg/kg), alfaxalone (1.5 mg/kg) and midazolam (0.2 mg/kg; HAM group), or hydromorphone (0.1 mg/kg) and alfaxalone (1.5 mg/kg; HA group). Sedation scoring (0–9, where 9 indicated maximum sedation) was performed at 0, 5, 10, 15 and 20 mins from the time of injection. At 20 mins, an IV catheter placement score (0–10, where 10 indicated least resistance) was performed. Results Twenty-one client-owned adult cats were included in this study. Sedation and IV catheter placement scores were compared between groups using Wilcoxon rank sum tests. Peak sedation was significantly higher ( P = 0.002) in the HAM group (median 9; range 7–9) than in the HA group (median 7; range 3–9), and IV catheter placement scores were significantly higher ( P = 0.001) in the HAM group (median 9.5; range 7–10) compared with the HA group (median 7; range 4–9). Spearman correlations were calculated between IV catheter placement score and sedation scores. There was a significant positive correlation of average sedation over time (correlation 0.83; P <0.001) and sedation at 20 mins (correlation 0.76; P <0.001) with a higher, more favorable IV catheter placement score. Conclusions and relevance These preliminary results suggest that the addition of midazolam to IM alfaxalone and hydromorphone produced more profound sedation and greater ease of IV catheter placement than IM alfaxalone and hydromorphone alone.

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