scholarly journals Burden of premature ventricular contractions beyond nonsustained ventricular tachycardia is related to the myocardial extracellular space expansion in patients with hypertrophic‐cardiomyopathy

2020 ◽  
Vol 43 (11) ◽  
pp. 1317-1325
Author(s):  
Hyemoon Chung ◽  
Chul‐Hwan Park ◽  
Yoonjung Kim ◽  
Jong‐Youn Kim ◽  
Pil‐Ki Min ◽  
...  
Keyword(s):  
Ventricular Tachycardia ◽  
Hypertrophic Cardiomyopathy ◽  
Extracellular Space ◽  
Premature Ventricular Contractions ◽  
Nonsustained Ventricular Tachycardia ◽  
Space Expansion

scholarly journals Myocardial extracellular space expansion is related to burden of premature ventricular contractions in patients with hypertrophic cardiomyopathy without non-sustained ventricular tachycardia

2021 ◽  
Vol 22 (Supplement_1) ◽  
Author(s):  
H Chung ◽  
CH Park ◽  
YJ Kim ◽  
JY Kim ◽  
PK Min ◽  
...  
Keyword(s):  
Ventricular Tachycardia ◽  
Hypertrophic Cardiomyopathy ◽  
Myocardial Fibrosis ◽  
Extracellular Space ◽  
Premature Ventricular Contraction ◽  
Sustained Ventricular Tachycardia ◽  
Premature Ventricular Contractions ◽  
Funding Sources ◽  
Space Expansion ◽  
Current Guidelines

Abstract Funding Acknowledgements Type of funding sources: None. Background Current guidelines suggest the presence of non-sustained ventricular tachycardia (NSVT) as a risk factor of sudden cardiac death in patients with hypertrophic cardiomyopathy (HCM). However, high burden of premature ventricular contraction (PVC) may reflect myocardial fibrosis although the absence of NSVT. Purpose We investigated the association between PVC burden and myocardial extracellular space expansion in HCM patients without NSVT. Methods Of the 212 patients prospectively enrolled to the HCM registry of genetics, 84 patients were evaluated with both cardiac magnetic resonance and 24hr holter. Among them, 71 patients (58 males, mean age: 71 ± 13 years) have not been diagnosed with NSVT. Results Patients with NSVT (n = 13) showed more impaired LA functional indices and higher myocardial fibrosis burden compared with patients without NSVT (n = 71). Among patients who have not been diagnosed with NSVT, patients with late gadolinium enhancement (LGE, n = 46) had a higher total beats (109 ± 332 vs. 7 ± 13 beats per a day, p = 0.003) and burden (0.114 ± 0.225 vs. 0.008 ± 0.014 %, p = 0.003) of PVC during 24-hour compared with patients without LGE (n = 25). %LGE was correlated with total beats of PVC (r = 0.358, p = 0.002) and PVC burden (r = 0.377, p = 0.001). ECV also correlated with total beats of PVC (r = 0.387, p = 0.001) and PVC burden (r = 0.401, p = 0.001). The optimal cutoff value for PVC number was 45 (37.0% of sensitivity and 100% of specificity) with 0.733 of the area under the ROC curve (p < 0.001). Pathogenic or likely pathogenic sarcomere mutation was higher in NSVT group than no NSVT group (p < 0.05), and had a higher tendency in higher PVC burden group (0.05 < p < 0.1) than lower PVC burden group. Conclusions Total beats and burden of PVC are significantly related to increase in myocardial fibrosis in HCM patients without NSVT. Abstract Figure. Mechanism of ventricular arrhythmia

Left ventricular mechanical dispersion is associated with nonsustained ventricular tachycardia in hypertrophic cardiomyopathy

2016 ◽  
Vol 48 (6) ◽  
pp. 417-427 ◽  
Author(s):  
Mikko Jalanko ◽  
Mika Tarkiainen ◽  
Petri Sipola ◽  
Pertti Jääskeläinen ◽  
Kirsi Lauerma ◽  
...  
Keyword(s):  
Ventricular Tachycardia ◽  
Hypertrophic Cardiomyopathy ◽  
Left Ventricular ◽  
Nonsustained Ventricular Tachycardia ◽  
Mechanical Dispersion

scholarly journals Prognosis of asymptomatic patients with hypertrophic cardiomyopathy and nonsustained ventricular tachycardia.

Circulation ◽  
1994 ◽  
Vol 90 (6) ◽  
pp. 2743-2747 ◽  
Author(s):  
P Spirito ◽  
C Rapezzi ◽  
C Autore ◽  
P Bruzzi ◽  
P Bellone ◽  
...  
Keyword(s):  
Ventricular Tachycardia ◽  
Hypertrophic Cardiomyopathy ◽  
Nonsustained Ventricular Tachycardia ◽  
Asymptomatic Patients

QT Variability Before and After Episodes of Nonsustained Ventricular Tachycardia in Patients with Hypertrophic Cardiomyopathy

1998 ◽  
Vol 21 (11) ◽  
pp. 2387-2391 ◽  
Author(s):  
NICK E. MEZILIS ◽  
FRAGISKOS I. PARTHENAKIS ◽  
MARINA K. KANAKARAKI ◽  
EMMANOUEL M. KANOUPAKIS ◽  
PANOS E. VARDAS
Keyword(s):  
Ventricular Tachycardia ◽  
Hypertrophic Cardiomyopathy ◽  
Nonsustained Ventricular Tachycardia ◽  
Before And After ◽  
Qt Variability

Risks associated with removal of ventricular epicardial pacing wires after cardiac surgery

1998 ◽  
Vol 7 (6) ◽  
pp. 444-449 ◽  
Author(s):  
KC Carroll ◽  
LM Reeves ◽  
G Andersen ◽  
FM Ray ◽  
PL Clopton ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Ventricular Tachycardia ◽  
Ventricular Arrhythmias ◽  
Premature Ventricular Contraction ◽  
Premature Ventricular Contractions ◽  
Convenience Sample ◽  
Nonsustained Ventricular Tachycardia ◽  
Electrocardiographic Monitoring ◽  
History Of ◽  
Epicardial Pacing

BACKGROUND: Epicardial pacing wires are routinely used for the diagnosis and treatment of bradyarrhythmias after cardiac surgery. The frequency of arrhythmias during removal of the wires is unknown, and methods of removal vary among institutions. OBJECTIVES: To describe the frequency of ventricular arrhythmias during removal of epicardial pacing wires from the right ventricle, to determine variables that are predictive of ventricular arrhythmias during wire removal, and to describe patients' perceptions of wire removal. METHODS: A convenience sample of 145 patients who had undergone cardiac surgery was studied during the course of 1 year. Electrocardiographic and vital signs were recorded throughout wire removal. Patients' records were reviewed for variables that could predict the occurrence of arrhythmias during wire removal: laboratory values, history of arrhythmias, medications, medical history, postoperative course, and pain reported by the patient. RESULTS: Sixty-six percent of patients had one premature ventricular contraction or more while the ventricular wires were being removed. Seven percent of patients had nonsustained ventricular tachycardia during wire removal. Patients who had repeat cardiac surgery had significantly more nonsustained ventricular tachycardia than did all other patients (P < .01). Only a history of heart failure (P < .02) was a significant predictor of premature ventricular contractions during wire removal. On a scale of 0 (no pain) to 10 (worst pain), the mean rating of pain intensity reported by patients was 2.39 (SD = 2.77). CONCLUSION: Patients may be at risk for ventricular arrhythmias during removal of epicardial pacing wires. Findings support the need for electrocardiographic monitoring while pacing wires are being removed.

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