scholarly journals Rate‐responsive pacing and atrial high rate episodes in cardiac resynchronization therapy patients: Is low heart rate the key?

2019 ◽  
Vol 42 (9) ◽  
pp. 820-828 ◽  
Author(s):  
Mauro Biffi ◽  
Antonio D'Onofrio ◽  
Carlo Pignalberi ◽  
Ennio C. Pisanò ◽  
Saverio Iacopino ◽  
...  
Keyword(s):  
Heart Rate ◽  
Cardiac Resynchronization Therapy ◽  
High Rate ◽  
Cardiac Resynchronization ◽  
Resynchronization Therapy ◽  
Rate Responsive

scholarly journals A Novel and Simple Exercise Test Parameter to Assess Responsiveness to Cardiac Resynchronization Therapy

Diagnostics ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 920
Author(s):  
Alina-Ramona Cozlac ◽  
Lucian Petrescu ◽  
Simina Crisan ◽  
Constantin Tudor Luca ◽  
Cristina Vacarescu ◽  
...  
Keyword(s):  
Heart Rate ◽  
Cardiac Resynchronization Therapy ◽  
Exercise Test ◽  
Heart Rate Recovery ◽  
Area Under The Curve ◽  
Left Ventricular ◽  
Cardiac Resynchronization ◽  
Reverse Remodeling ◽  
Resynchronization Therapy ◽  
Acceleration And Deceleration

This study assessed the value of heart rate recovery index (HRRI), a new parameter of an exercise test, as the predictor of response to cardiac resynchronization therapy (CRT). Methods: Consecutive patients receiving a CRT device were followed up after implantation and every 6 months. An effort test (ET) was quantified by minimum heart rate/maximum heart rate, as well as acceleration and deceleration times. HRRI was calculated as the ratio between acceleration and deceleration time (AT/DT) and compared to outcome. We used logistic regression to assess the predictive value of HRRI for responders and non-responders to CRT. The area under the curve (AUC) was computed to distinguish between positive and negative outcomes. Results: A total of 109 patients (74 men, mean age 63.3 ± 9.8 years) were analyzed; permanent long-term fusion CRT pacing was possible in 65 patients. Patients were assigned to two groups: responders and non-responders (98/11 patients). During a mean follow-up of 36 months, 545 ETs were performed. HRRI was significantly higher in responders versus non-responders (3.16 ± 2 vs. 1.4 ± 0.5, p < 0.001). The optimal cutoff value for HRRI as a predictor of CRT response was 1.51 (area under the receiver operating characteristic (ROC) curve = 0.844). Responders had significant left-ventricular (LV) reverse remodeling (LV end-diastolic volume = 240 ± 90 mL vs. 217 ± 89 mL, p < 0.001) and higher LV ejection fraction (26 ± 5.8% vs. 35 ± 8.7%, p < 0.001). Conclusions: HRRI computation during routine ET is useful for the evaluation of responsiveness to CRT.

Heart rate and dyssynchrony in patients with cardiac resynchronization therapy: a pilot study

2017 ◽  
Vol 51 (3) ◽  
pp. 143-152
Author(s):  
Jan Naar ◽  
Lars Mortensen ◽  
Reidar Winter ◽  
Jonas Johnson ◽  
Kambiz Shahgaldi ◽  
...  
Keyword(s):  
Heart Rate ◽  
Pilot Study ◽  
Cardiac Resynchronization Therapy ◽  
Cardiac Resynchronization ◽  
Resynchronization Therapy
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