scholarly journals Eicosapentaenoic acid therapy is associated with decreased coronary plaque instability assessed using optical frequency domain imaging

2019 ◽  
Vol 42 (6) ◽  
pp. 618-628 ◽  
Author(s):  
Takao Konishi ◽  
Daisuke Sunaga ◽  
Naohiro Funayama ◽  
Tadashi Yamamoto ◽  
Hironori Murakami ◽  
...  
Keyword(s):  
Eicosapentaenoic Acid ◽  
Frequency Domain ◽  
Coronary Plaque ◽  
Optical Frequency ◽  
Acid Therapy ◽  
Optical Frequency Domain Imaging ◽  
Plaque Instability

scholarly journals Obstructive sleep apnea is associated with increased coronary plaque instability: an optical frequency domain imaging study

2019 ◽  
Vol 34 (8) ◽  
pp. 1266-1279
Author(s):  
Takao Konishi ◽  
Yusuke Kashiwagi ◽  
Naohiro Funayama ◽  
Tadashi Yamamoto ◽  
Hironori Murakami ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Frequency Domain ◽  
Imaging Study ◽  
Coronary Plaque ◽  
Optical Frequency ◽  
Optical Frequency Domain Imaging ◽  
Plaque Instability ◽  
Obstructive Sleep

P5366Eicosapentaenoic acid therapy is associated with decreased coronary plaque instability assessed using optical frequency domain imaging

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
T Konishi
Keyword(s):  
Acute Coronary Syndrome ◽  
Coronary Artery ◽  
Frequency Domain ◽  
Density Lipoprotein ◽  
Coronary Plaque ◽  
Cholesterol Concentration ◽  
Optical Frequency ◽  
Plaque Instability ◽  
Coronary Syndrome ◽  
Lipid Index

Abstract Background The relationship between eicosapentaenoic acid (EPA) therapy and coronary plaque stability assessed by optical frequency domain imaging (OFDI) has not been thoroughly described. Hypothesis EPA therapy is associated with decreased plaque instability in patients undergoing percutaneous coronary intervention (PCI) using OFDI. Methods Data on coronary artery plaques from 121 patients presenting with acute coronary syndrome or stable angina who consecutively underwent PCI between October 2015 and July 2018 were retrospectively analyzed. Of these patients, 109 were untreated (no-EPA group), whereas 12 were treated with EPA (EPA group). Each plaque's morphological characteristics were analyzed using OFDI. Results We used 1:4 propensity score matching for patients who received or did not receive EPA therapy before PCI. Baseline characteristics were balanced between both groups (age, sex, body mass index, diabetes mellitus, hypertension, dyslipidemia, chronic kidney disease, smoking, previous PCI or coronary artery bypass grafting, previous myocardial infarction, prior statin use, acute coronary syndrome, hemoglobin A1c level, low-density lipoprotein cholesterol concentration, triglyceride concentration, and high-density lipoprotein cholesterol concentration). The EPA group had significantly lower mean lipid index (818±806 vs. 1,574±891) and macrophage grade (13.5±5.9 vs. 19.3±7.4) but higher mean minimum fibrous cap thickness (109.2±55.7 vs. 81.6±36.4 μm) than the no-EPA group (P=0.010, 0.019, and 0.040, respectively). Multiple logistic regression analyses showed that prior EPA use was independently associated with lower lipid index and macrophage grade (P=0.043 and 0.024, respectively). Conclusion This OFDI analysis suggests that EPA therapy is associated with decreased plaque instability in patients undergoing PCI. Acknowledgement/Funding None

Microball lens integrated fiber probe for optical frequency domain imaging

2011 ◽  
Vol 9 (9) ◽  
pp. 090608-90610 ◽  
Author(s):  
Jae-Ho Han Jae-Ho Han ◽  
J. U. Kang J. U. Kang
Keyword(s):  
Frequency Domain ◽  
Optical Frequency ◽  
Fiber Probe ◽  
Optical Frequency Domain Imaging

scholarly journals Comprehensive microscopy of the esophagus in human patients with optical frequency domain imaging

2008 ◽  
Vol 68 (4) ◽  
pp. 745-753 ◽  
Author(s):  
Melissa J. Suter ◽  
Benjamin J. Vakoc ◽  
Patrick S. Yachimski ◽  
Milen Shishkov ◽  
Gregory Y. Lauwers ◽  
...  
Keyword(s):  
Frequency Domain ◽  
Optical Frequency ◽  
Optical Frequency Domain Imaging
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