scholarly journals High-Sensitivity Cardiac Troponin T in Stable Patients Undergoing Pharmacological Stress Testing

2015 ◽  
Vol 38 (5) ◽  
pp. 293-299 ◽  
Author(s):  
Nattawut Wongpraparut ◽  
Sudarat Piyophirapong ◽  
Adisak Maneesai ◽  
Kosit Sribhen ◽  
Rungroj Krittayaphong ◽  
...  
Keyword(s):  
Cardiac Troponin ◽  
Stress Testing ◽  
Troponin T ◽  
High Sensitivity ◽  
Cardiac Troponin T ◽  
Pharmacological Stress ◽  
Pharmacological Stress Testing

Evaluation of the 0 h/1 h high-sensitivity cardiac troponin T algorithm in diagnosis of non-ST-segment elevation myocardial infarction (NSTEMI) in Han population

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Chen Dongxu ◽  
Zhou Yannan ◽  
Yang Yilin ◽  
Yao Chenling ◽  
Gu Guorong ◽  
...  
Keyword(s):  
Cardiac Troponin ◽  
Troponin T ◽  
High Sensitivity ◽  
Cardiac Troponin T ◽  
Chinese Han ◽  
Han Population ◽  
St Segment Elevation ◽  
Segment Elevation Myocardial Infarction ◽  
St Segment ◽  
Rule Out

Abstract Objectives A rapid 0 h/1 h algorithm using high-sensitivity cardiac troponin T (hs-cTnT) for rule-out and rule-in of non-ST-segment elevation myocardial infarction (NSTEMI) is recommended by the European Society of Cardiology. We aim to prospectively evaluate the diagnostic performance of the algorithm in Chinese Han patients with suspected NSTEMI. Methods In this prospective diagnostic cohort study, 577 patients presenting to the emergency department with suspected NSTEMI and recent (<12 h) onset of symptoms were enrolled. The levels of serum hs-cTnT were measured on admission, 1 h later and 4–14 h later. All patients underwent the initial clinical assessment and were triaged into three groups (rule-out, rule-in and observe) according to the 0 h/1 h algorithm. The major cardiovascular events (MACE) were evaluated at the 7-day and 30-day follow-ups. Results Among 577 enrolled patients, NSTEMI was the final diagnosis for 106 (18.4%) patients. Based on the hs-cTnT 0 h/1 h algorithm, 148 patients (25.6%) were classified as rule-out, 278 patients (48.2%) as rule-in and 151 patients (26.2%) were assigned to the observe group. The rule-out approach resulted in a sensitivity of 100% and negative predictive value of 100%. The rule-in approach resulted in a specificity of 62.9% [95% CI (58.5–67.2%)] and positive predictive value of 37.1% [95%CI (31.3–42.8%)]. No MACE was observed in the rule-out group within 30-day follow-up. Conclusions The hs-cTnT 0 h/1 h algorithm is a safe tool for early rule-out of NSTEMI, while probably not an effective strategy for accurate rule-in of NSTEMI in Chinese Han population.

scholarly journals SOLUBLE ST2 AND HIGH SENSITIVITY CARDIAC TROPONIN-T LEVELS PREDICT ATRIAL FIBRILLATION ABLATION OUTCOME

2016 ◽  
Vol 67 (13) ◽  
pp. 840
Author(s):  
Vincent Y. See ◽  
Timm Dickfeld ◽  
Stephen Shorofsky ◽  
Anastasios Saliaris ◽  
Benjamin Remo ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Cardiac Troponin ◽  
Troponin T ◽  
High Sensitivity ◽  
Atrial Fibrillation Ablation ◽  
Cardiac Troponin T ◽  
Soluble St2
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