scholarly journals Guideline-based Discharge Therapy for Unstable Angina Pectoris/Non-ST Elevation Myocardial Infarction

2007 ◽  
Vol 30 (10) ◽  
pp. 489-490
Author(s):  
C. Richard Conti
Keyword(s):  
Myocardial Infarction ◽  
Angina Pectoris ◽  
Unstable Angina ◽  
St Elevation Myocardial Infarction ◽  
Unstable Angina Pectoris ◽  
St Elevation

scholarly journals Patients aged 80 years or older with non-ST-elevation myocardial infarction or unstable angina pectoris randomised to an invasive versus conservative strategy: angiographic and procedural results from the After Eighty study

Open Heart ◽  
2020 ◽  
Vol 7 (2) ◽  
pp. e001256
Author(s):  
Nicolai Tegn ◽  
Christian Eek ◽  
Michael Abdelnoor ◽  
Lars Aaberge ◽  
Knut Endresen ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Angina Pectoris ◽  
Unstable Angina ◽  
St Elevation Myocardial Infarction ◽  
Unstable Angina Pectoris ◽  
Metal Stents ◽  
Conservative Strategy ◽  
Vessel Disease ◽  
Link Type ◽  
St Elevation

ObjectivesWe aimed to report the angiographic and procedural results of the After Eighty study (ClinicalTrials.gov, NCT01255540), and to identify independent predictors of revascularisation.MethodsPatients of ≥80 years old with non-ST-elevation myocardial infarction and unstable angina pectoris were randomised to an invasive or conservative strategy. Angiographic and procedural results were recorded. Univariate and multivariate analyses were performed to explore variables predicting revascularisation.ResultsAmong 229 patients in the invasive group, 220 underwent immediate coronary angiography (90% performed via the radial artery). Of these patients, 48% had three-vessel disease or left main stenosis, 18% two-vessel disease, 16% one-vessel disease, 17% minor coronary vessel wall changes and two patients had normal coronary arteries. Six patients (3%) underwent coronary artery bypass graft. Percutaneous coronary intervention (PCI) was performed in 107 patients (49%), with 57% treated with bare metal stents, 37% drug-eluting stents and 6% balloon angioplasty. On average, 1.7 lesions were treated and 2 stents delivered per patient. Complications included 1 major PCI-related bleeding (successfully treated), 2 minor access site-related bleedings, 3 side branch occlusions during PCI and 11 periprocedural myocardial infarctions (considered end points). Sex, bundle branch block and smoking were independent predictors of revascularisation.ConclusionsPCI was performed in approximately half of the patients, similar to findings in younger populations. Procedural success was high, with few complications.Trial registration numberNCT01255540

Is the neutrophil-lymphocyte ratio a good marker for the differential diagnosis of unstable angina pectoris and non-ST elevation myocardial infarction?

2021 ◽  
pp. 13-18
Keyword(s):  
Myocardial Infarction ◽  
Differential Diagnosis ◽  
Angina Pectoris ◽  
Unstable Angina ◽  
St Elevation Myocardial Infarction ◽  
Unstable Angina Pectoris ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Good Marker ◽  
St Elevation

Background: The aim of this study is to investigate the role of the neutrophil-lymphocyte ratio (NLR) in the differential diagnosis of non-ST elevation myocardial infarction (NSTEMI) and unstable angina pectoris (USAP). Material and Method: Patients who had been admitted to the emergency ward with complaints of chest pain and who were diagnosed with USAP and NSTEMI in further examination were retrospectively included in this study. The NLR level was measured for each patient both at the times of application and of discharge. The NLR was calculated by dividing the neutrophil count by the lymphocyte count. Results: WBC (8107.38±1405.5 vs 7452.46±1427.9, p: 0.020), neutrophil (5620 vs 4300, p: 0.001), and NLR (3.86 vs 2.14, p: 0.001) values were higher, whereas the lymphocyte value (1505 vs 2100, p: 0.001) was lower in the NSTEMI versus the USAP group. According to the multivariable logistic regression analysis that was done, NLR appeared to be an independent predictor of NSTEMI. The predictive value of NLR for NSTEMI diagnosis was >3.22 with 61.9% sensitivity and 86.96% specificity (74.3% positive predictive, 78.9% negative predictive) (AUC: 0.761; p< 0.001). Conclusion: As a cheap inexpensive and easy-to-calculate index that can be applied in every medical establishment within the first 20 minutes of application, it is possible to state that NLR is a good marker in distinguishing NSTEMI from USAP patients.

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