Deoxyfluorination of carboxylic, sulfonic, phosphinic acids and phosphine oxides by PFECA featuring CF 2 O units

2021 ◽  
Author(s):  
Shiyu Zhao ◽  
Yong Guo ◽  
Zhaoben Su ◽  
Chengying Wu ◽  
Wei Chen ◽  
...  
Keyword(s):  
Phosphine Oxides ◽  
Phosphinic Acids

Microwave irradiation and catalysis in organophosphorus reactions

2019 ◽  
Vol 91 (1) ◽  
pp. 145-157 ◽  
Author(s):  
György Keglevich ◽  
Nóra Zsuzsa Kiss ◽  
Réka Henyecz ◽  
Zoltán Mucsi
Keyword(s):  
Microwave Irradiation ◽  
Aryl Halides ◽  
Arbuzov Reaction ◽  
Phosphine Oxides ◽  
Direct Esterification ◽  
Phosphinic Acids ◽  
Mw Irradiation ◽  
Organophosphorus Chemistry ◽  
Active Methylene ◽  
The Arbuzov Reaction

AbstractThe usual advantage of microwave (MW) assistance is making organic reactions faster and more efficient. In this article we present reaction types from organophosphorus chemistry, when MW-assisted transformations (e.g. the direct esterification and alkylating esterification of phosphinic acids) may be promoted by suitable catalysts, or vice versa, when a catalytic reaction is enhanced by MW irradiation (e.g. the Arbuzov reaction of aryl halides), and when catalysts may be omitted or simplified under MW irradiation as shown by the alkylation of active methylene containing P=O substrates/the Kabachnik–Fields reaction/deoxygenation of phosphine oxides, and the Hirao reaction, respectively.

Advantages of the Microwave Tool in Organophosphorus Syntheses

Synthesis ◽  
2017 ◽  
Vol 49 (14) ◽  
pp. 3069-3083 ◽  
Author(s):  
György Keglevich ◽  
Nóra Kiss ◽  
Alajos Grün ◽  
Erika Bálint ◽  
Tamara Kovács
Keyword(s):  
Liquid Phase ◽  
Phosphine Oxides ◽  
Catalytic Systems ◽  
Phosphinic Acids ◽  
Mw Irradiation ◽  
Catalyst Systems ◽  
The One ◽  
Solid Liquid ◽  
Active Methylene ◽  
P Ligands

The microwave (MW) technique has become an important tool also in the organophosphorus field of organic chemistry. On the one hand, otherwise reluctant reactions, such as the esterification of P-acids, may be enhanced by the effect of MW, while on the other hand, catalysts may be omitted, or catalyst systems may be simplified on MW irradiation. This later group includes the Kabachnik–Fields reactions, alkylation of active methylene-containing compounds, O-alkylations, deoxygenations, as well as the Hirao reaction. It is also the purpose of this review to elucidate the scope and limitations of the MW tool, to interpret the MW effects, and to model the distribution of local overheatings and their beneficial effect.1 Introduction2 The Esterification of Phosphinic Acids2.1 Synthetic Results2.2 Scope and Limitation of the Application of MWs2.3 Modelling the Distribution of the Local Overheatings and Predicting­ Their Effect3 The Simplification of Catalytic Systems3.1 Replacement of the Catalyst by MW Irradiation3.1.1 The Kabachnik–Fields Reaction3.1.2 Solid–Liquid Phase Alkylation of Active Methylene-Containing Compounds3.1.3 Solid–Liquid Phase Alkylation of Phosphinic Acids3.1.4 The Deoxygenation of Phosphine Oxides3.2 The Hirao Reaction without Added P-Ligands4 Conclusions

Bis(hydroxymethyl)phosphine Oxides and Hydroxymethyl Phosphinic Acids as Phosphonic Acid Analogs

2002 ◽  
Vol 177 (8-9) ◽  
pp. 2221-2222 ◽  
Author(s):  
J. L. Pirat ◽  
C. Brahic ◽  
C. Ciptadi ◽  
H. J. Cristau ◽  
A. Hervé ◽  
...  
Keyword(s):  
Phosphonic Acid ◽  
Phosphine Oxides ◽  
Phosphinic Acids
Sign in / Sign up

Export Citation Format

Share Document