Overcome Debye Length Limitations for Biomolecule Sensing based on Field Effective Transistors

2020 ◽  
Author(s):  
Zhi Zheng ◽  
Hongyuan Zhang ◽  
Tianyou Zhai ◽  
Fan Xia
Keyword(s):  
Debye Length ◽  
Biomolecule Sensing

scholarly journals Influence of the Electrolyte Salt Concentration on DNA Detection with Graphene Transistors

Biosensors ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 24
Author(s):  
Agnes Purwidyantri ◽  
Telma Domingues ◽  
Jérôme Borme ◽  
Joana Rafaela Guerreiro ◽  
Andrey Ipatov ◽  
...  
Keyword(s):  
Phosphate Buffer ◽  
Species Interactions ◽  
Field Effect ◽  
Field Effect Transistors ◽  
Limit Of Detection ◽  
Debye Length ◽  
Intermolecular Forces ◽  
Single Layer Graphene ◽  
Dna Adsorption

Liquid-gated Graphene Field-Effect Transistors (GFET) are ultrasensitive bio-detection platforms carrying out the graphene’s exceptional intrinsic functionalities. Buffer and dilution factor are prevalent strategies towards the optimum performance of the GFETs. However, beyond the Debye length (λD), the role of the graphene-electrolytes’ ionic species interactions on the DNA behavior at the nanoscale interface is complicated. We studied the characteristics of the GFETs under different ionic strength, pH, and electrolyte type, e.g., phosphate buffer (PB), and phosphate buffer saline (PBS), in an automatic portable built-in system. The electrostatic gating and charge transfer phenomena were inferred from the field-effect measurements of the Dirac point position in single-layer graphene (SLG) transistors transfer curves. Results denote that λD is not the main factor governing the effective nanoscale screening environment. We observed that the longer λD was not the determining characteristic for sensitivity increment and limit of detection (LoD) as demonstrated by different types and ionic strengths of measuring buffers. In the DNA hybridization study, our findings show the role of the additional salts present in PBS, as compared to PB, in increasing graphene electron mobility, electrostatic shielding, intermolecular forces and DNA adsorption kinetics leading to an improved sensitivity.

Dynamic Biomolecule Sensing Bead Array Held by Optical Tweezers

2011 ◽  
Author(s):  
Mael Manesse ◽  
Christopher N. Lafratta ◽  
Manuel A. Palacios ◽  
Aaron F. Phillips ◽  
David R. Walt
Keyword(s):  
Optical Tweezers ◽  
Biomolecule Sensing

scholarly journals Nano-channel-based physical and chemical synergic regulation for dendrite-free lithium plating

Nano Research ◽  
2021 ◽  
Author(s):  
Qiang Guo ◽  
Wei Deng ◽  
Shengjie Xia ◽  
Zibo Zhang ◽  
Fei Zhao ◽  
...  
Keyword(s):  
Carbon Materials ◽  
Coating Layer ◽  
Effective Interaction ◽  
Debye Length ◽  
Rate Capability ◽  
Negative Electrode ◽  
Lithium Ion ◽  
Positive Electrode ◽  
Lithium Metal ◽  
Interaction Distance

AbstractUncontrollable dendrite growth resulting from the non-uniform lithium ion (Li+) flux and volume expansion in lithium metal (Li) negative electrode leads to rapid performance degradation and serious safety problems of lithium metal batteries. Although N-containing functional groups in carbon materials are reported to be effective to homogenize the Li+ flux, the effective interaction distance between lithium ions and N-containing groups should be relatively small (down to nanometer scale) according to the Debye length law. Thus, it is necessary to carefully design the microstructure of N-containing carbon materials to make the most of their roles in regulating the Li+ flux. In this work, porous carbon nitride microspheres (PCNMs) with abundant nanopores have been synthesized and utilized to fabricate a uniform lithiophilic coating layer having hybrid pores of both the nano- and micrometer scales on the Cu/Li foil. Physically, the three-dimensional (3D) porous framework is favorable for absorbing volume changes and guiding Li growth. Chemically, this coating layer can render a suitable interaction distance to effectively homogenize the Li+ flux and contribute to establishing a robust and stable solid electrolyte interphase (SEI) layer with Li-F, Li-N, and Li-O-rich contents based on the Debye length law. Such a physical-chemical synergic regulation strategy using PCNMs can lead to dendrite-free Li plating, resulting in a low nucleation overpotential and stable Li plating/stripping cycling performance in both the Li‖Cu and the Li‖Li symmetric cells. Meanwhile, a full cell using the PCNM coated Li foil negative electrode and a LiFePO4 positive electrode has delivered a high capacity retention of ∼ 80% after more than 200 cycles at 1 C and achieved a remarkable rate capability. The pouch cell fabricated by pairing the PCNM coated Li foil negative electrode with a NCM 811 positive electrode has retained ∼ 73% of the initial capacity after 150 cycles at 0.2 C.

Effects of repeated interactions and correlational disintegration on kinetic and transport properties of a non-neutral plasma in strong fields

1990 ◽  
Vol 44 (1) ◽  
pp. 167-190 ◽  
Author(s):  
Alf H. Øien
Keyword(s):  
Magnetic Field ◽  
Particle Transport ◽  
Axial Magnetic Field ◽  
Debye Length ◽  
Electron Plasma ◽  
Larmor Radius ◽  
Equilibration Time ◽  
Cylindrically Symmetric ◽  
Electric Potentials ◽  
Good Agreement

Collisions in a cylindrically symmetric non-neutral (electron) plasma, where the Larmor radius is much smaller than the Debye length, and the consequent particle transport, are studied. The plasma is confined radially by a strong axial magnetic field and axially by electric potentials. Hence two particles may interact repeatedly. Eventually they drift too far away from each other poloidally to interact any more, owing to shear in the E × B drift. The consequent build-up of correlation is limited by correlational disintegration due to collisions with ‘third particles’ between the repeated interactions. A kinetic equation including these effects is derived, and the cross-field particle transport along the density gradient is found. An associated equilibration time is shown to scale as B and to be in good agreement with the experimentally obtained values of Briscoli, Malmberg and Fine.

scholarly journals Numerical Simulation of the Time Evolution of Small-Scale Irregularities in the F-Layer Ionospheric Plasma

2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
O. V. Mingalev ◽  
G. I. Mingaleva ◽  
M. N. Melnik ◽  
V. S. Mingalev
Keyword(s):  
Magnetic Field ◽  
Time Evolution ◽  
Ionospheric Plasma ◽  
Debye Length ◽  
Small Scale ◽  
System Of Equations ◽  
Applied Model ◽  
Positive Ions ◽  
F Region ◽  
Small Scale Irregularity

Dynamics of magnetic field-aligned small-scale irregularities in the electron concentration, existing in the F-layer ionospheric plasma, is investigated with the help of a mathematical model. The plasma is assumed to be a rarefied compound consisting of electrons and positive ions and being in a strong, external magnetic field. In the applied model, kinetic processes in the plasma are simulated by using the Vlasov-Poisson system of equations. The system of equations is numerically solved applying a macroparticle method. The time evolution of a plasma irregularity, having initial cross-section dimension commensurable with a Debye length, is simulated during the period sufficient for the irregularity to decay completely. The results of simulation indicate that the small-scale irregularity, created initially in the F-region ionosphere, decays accomplishing periodic damped vibrations, with the process being collisionless.

ASYMPTOTIC STABILITY OF EQUILIBRIUM STATES FOR AMBIPOLAR PLASMAS

2004 ◽  
Vol 14 (09) ◽  
pp. 1361-1399 ◽  
Author(s):  
V. GIOVANGIGLI ◽  
B. GRAILLE
Keyword(s):  
Partial Differential Equations ◽  
Asymptotic Stability ◽  
Differential Equations ◽  
Null Space ◽  
Current Model ◽  
Debye Length ◽  
Equilibrium States ◽  
Electron Mass ◽  
Partial Differential ◽  
Stability Of Equilibrium

We investigate a system of partial differential equations modeling ambipolar plasmas. The ambipolar — or zero current — model is obtained from general plasmas equations in the limit of vanishing Debye length. In this model, the electric field is expressed as a linear combination of macroscopic variable gradients. We establish that the governing equations can be written as a symmetric form by using entropic variables. The corresponding dissipation matrices satisfy the null space invariant property and the system of partial differential equations can be written as a normal form, i.e. in the form of a symmetric hyperbolic–parabolic composite system. By properly modifying the chemistry source terms and/or the diffusion matrices, asymptotic stability of equilibrium states is established and decay estimates are obtained. We also establish the continuous dependence of global solutions with respect to vanishing electron mass.

Asymptotically matched sheath and presheath in a dense plasma

1998 ◽  
Vol 59 (3) ◽  
pp. 505-536 ◽  
Author(s):  
LINDSEY D. THORNHILL ◽  
PRATEEN V. DESAI
Keyword(s):  
Rapid Change ◽  
Debye Length ◽  
Mean Free Path ◽  
Boundary Region ◽  
Surface Erosion ◽  
Leading Order ◽  
Power Flux ◽  
Temperature Plasma ◽  
Recombination Length ◽  
The Impact

Asymptotically matched solutions for electron and ion density, electron and ion velocity, and electric potential are obtained in the boundary region of a dense low-temperature plasma adjacent to perfectly absorbing walls – walls that absorb, without reflection, incident electrons and ions. Leading-order composite solutions, valid throughout the boundary region, are constructed from solutions in three subdomains distinguished by different physical length scales: the geometric length, the ion mean free path and the Debye length. The composite solutions are used to assess the impact of electron–ion recombination in the ionization nonequilibrium region on sheath and presheath profiles, and on quantities evaluated at the wall. While, at leading order, the velocity profiles throughout the boundary region are not influenced by recombination, the density and potential profiles are significantly altered when recombination is included. These results show that the region of rapid change in these profiles lies closer to the wall when recombination is explicitly included in the model. The influence of recombination on the presheath potential, and consequently the wall potential, is found to scale as the natural logarithm of the recombination length. The broadening of the density profile results in a larger flux of ions accelerating through the sheath and impacting on the wall. The influence of recombination on the ion power flux to the wall is found to scale with the inverse recombination length. This scaling influences the prediction of surface erosion rates in technological applications that utilize these plasmas.

Direct Measurement of Sub-Debye-Length Attraction between Oppositely Charged Surfaces

2009 ◽  
Vol 103 (11) ◽  
Author(s):  
Nir Kampf ◽  
Dan Ben-Yaakov ◽  
David Andelman ◽  
S. A. Safran ◽  
Jacob Klein
Keyword(s):  
Direct Measurement ◽  
Debye Length ◽  
Charged Surfaces ◽  
Oppositely Charged
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