Rationally Design of Near Infrared Light Responsive Micro‐Photoelectrodes for In Vivo Sensing of Neurotransmitter Molecules in Mouse Brain †

2020 ◽  
Vol 38 (3) ◽  
pp. 275-281
Author(s):  
Yina Zhao ◽  
Wenlong Wu ◽  
Baihe Fu ◽  
Liyong Gan ◽  
Zhonghai Zhang
Keyword(s):  
Mouse Brain ◽  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light ◽  
In Vivo Sensing

In Vivo Monitoring of Intravenously Injected Gold Nanorods Using Near‐Infrared Light

Small ◽  
2008 ◽  
Vol 4 (7) ◽  
pp. 1001-1007 ◽  
Author(s):  
Takuro Niidome ◽  
Yasuyuki Akiyama ◽  
Kohei Shimoda ◽  
Takahito Kawano ◽  
Takeshi Mori ◽  
...  
Keyword(s):  
Gold Nanorods ◽  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light ◽  
In Vivo Monitoring

scholarly journals In vivo performance of near-infrared light transillumination for dentine proximal caries detection in permanent teeth

2020 ◽  
Vol 32 (4) ◽  
pp. 187-193
Author(s):  
Ayşe Dündar ◽  
Mehmet Ertuğrul Çiftçi ◽  
Özlem İşman ◽  
Ali Murat Aktan
Keyword(s):  
Near Infrared ◽  
Infrared Light ◽  
Caries Detection ◽  
Permanent Teeth ◽  
Near Infrared Light ◽  
Proximal Caries

scholarly journals Powering rotary molecular motors with low-intensity near-infrared light

2020 ◽  
Vol 6 (44) ◽  
pp. eabb6165
Author(s):  
Lukas Pfeifer ◽  
Nong V. Hoang ◽  
Maximilian Scherübl ◽  
Maxim S. Pshenichnikov ◽  
Ben L. Feringa
Keyword(s):  
Smart Materials ◽  
Molecular Motors ◽  
Near Infrared ◽  
In Vivo Studies ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Two Photon ◽  
Low Intensity

Light-controlled artificial molecular machines hold tremendous potential to revolutionize molecular sciences as autonomous motion allows the design of smart materials and systems whose properties can respond, adapt, and be modified on command. One long-standing challenge toward future applicability has been the need to develop methods using low-energy, low-intensity, near-infrared light to power these nanomachines. Here, we describe a rotary molecular motor sensitized by a two-photon absorber, which efficiently operates under near-infrared light at intensities and wavelengths compatible with in vivo studies. Time-resolved spectroscopy was used to gain insight into the mechanism of energy transfer to the motor following initial two-photon excitation. Our results offer prospects toward in vitro and in vivo applications of artificial molecular motors.

Near-Infrared Light Dual-Promoted Heterogeneous Copper Nanocatalyst for Highly Efficient Bioorthogonal Chemistry in Vivo

ACS Nano ◽  
2020 ◽  
Vol 14 (4) ◽  
pp. 4178-4187 ◽  
Author(s):  
Yawen You ◽  
Fangfang Cao ◽  
Yajie Zhao ◽  
Qingqing Deng ◽  
Yanjuan Sang ◽  
...  
Keyword(s):  
Near Infrared ◽  
Infrared Light ◽  
Bioorthogonal Chemistry ◽  
Near Infrared Light ◽  
Highly Efficient

Near-infrared light controlled fluorogenic labeling of glycoengineered sialic acids in vivo with upconverting photoclick nanoprobe

Nanoscale ◽  
2020 ◽  
Vol 12 (18) ◽  
pp. 10361-10368
Author(s):  
Yunxia Wu ◽  
Judun Zheng ◽  
Da Xing ◽  
Tao Zhang
Keyword(s):  
Near Infrared ◽  
Sialic Acids ◽  
Infrared Light ◽  
Near Infrared Light

Spatiotemporally controllable platform enables in situ fluorogenic labeling of alkene sialic acids based upconverting photoclick nanoprobe.

Intracellular Self‐Immolative Polyprodrug with Near‐Infrared Light Guided Accumulation and in Vivo Visualization of Drug Release

2021 ◽  
pp. 2109528
Author(s):  
Dong‐Bing Cheng ◽  
Xue‐Hao Zhang ◽  
Si‐Yi Chen ◽  
Xiao‐Xue Xu ◽  
Hao Wang ◽  
...  
Keyword(s):  
Drug Release ◽  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light

scholarly journals Hyaluronate modified upconversion nanoparticles for near infrared light-triggered on–off tattoo systems

RSC Advances ◽  
2017 ◽  
Vol 7 (24) ◽  
pp. 14805-14808 ◽  
Author(s):  
Seulgi Han ◽  
Songeun Beack ◽  
Sanghwa Jeong ◽  
Byung Woo Hwang ◽  
Myeong Hwan Shin ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
Near Infrared ◽  
Infrared Light ◽  
Upconversion Nanoparticles ◽  
Near Infrared Light ◽  
Nir Light

We successfully developed an NIR light-triggered in vivo on–off tattoo system using hyaluronate modified upconversion nanoparticles for various biomedical applications.

scholarly journals Near-infrared light and tumor microenvironment dual responsive size-switchable nanocapsules for multimodal tumor theranostics

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Zhiyi Wang ◽  
Yanmin Ju ◽  
Zeeshan Ali ◽  
Hui Yin ◽  
Fugeng Sheng ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Tumor Microenvironment ◽  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light ◽  
In Vivo Experiments ◽  
Dual Responsive ◽  
Synthetic Strategy ◽  
Scientific Challenge

Abstract Smart drug delivery systems (SDDSs) for cancer treatment are of considerable interest in the field of theranostics. However, developing SDDSs with early diagnostic capability, enhanced drug delivery and efficient biodegradability still remains a scientific challenge. Herein, we report near-infrared light and tumor microenvironment (TME), dual responsive as well as size-switchable nanocapsules. These nanocapsules are made of a PLGA-polymer matrix coated with Fe/FeO core-shell nanocrystals and co-loaded with chemotherapy drug and photothermal agent. Smartly engineered nanocapsules can not only shrink and decompose into small-sized nanodrugs upon drug release but also can regulate the TME to overproduce reactive oxygen species for enhanced synergistic therapy in tumors. In vivo experiments demonstrate that these nanocapsules can target to tumor sites through fluorescence/magnetic resonance imaging and offer remarkable therapeutic results. Our synthetic strategy provides a platform for next generation smart nanocapsules with enhanced permeability and retention effect, multimodal anticancer theranostics, and biodegradability.

In vivo Monitoring of Gold Nanorods and Tissue Damage Mediated with Their Photothermal Effect

2008 ◽  
Vol 1138 ◽  
Author(s):  
Takuro Niidome ◽  
Yasuyuki Akiyama ◽  
Kohei Shimoda ◽  
Takahito Kawano ◽  
Takeshi Mori ◽  
...  
Keyword(s):  
Surface Plasmon ◽  
Gold Nanorods ◽  
Near Infrared ◽  
Tumor Therapy ◽  
Infrared Light ◽  
Photothermal Effect ◽  
Integrating Sphere ◽  
Plasmon Band ◽  
Near Infrared Light

AbstractGold nanorods have a strong surface plasmon band at the near infrared region. The absorbed light energy is then converted to heat. Since near infrared light can penetrate deeply into tissue, gold nanorods are expected to be used as a contrast agent for bioimaging using the near infrared light and photosensitizers for photothermal therapy. The surface plasmon bands of intravenously injected the gold nanorods were directly monitored from the mouse abdomen by using a spectrophotometer equipped with an integrating sphere. The absorbance at 900 nm from PEG5,000-modified gold nanorods immediately increased after injection and reached a plateau. The injection of phosphatidylcholine-modified gold nanorods also increased the absorbance at 900 nm, but the absorbance decreased single exponentially with a 1.3-min half-life. To demonstrate photothermal tumor therapy, the PEG-modified gold nanorods were directly injected into subcutaneous tumors in mice, then, near infrared laser light was irradiated to the tumor. After the treatment, significant suppression of tumor growth was observed.

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