Thermodynamic Analysis of the Interaction between Cationic Porphyrins and Human Serum Albumin by an Optical Biosensor

2005 ◽  
Vol 23 (8) ◽  
pp. 1095-1099 ◽  
Author(s):  
Qin Yi-Min ◽  
Pan Ni-Na ◽  
Jian Yong-Xing ◽  
Li Zao-Ying ◽  
Zou Guo-Lin
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Thermodynamic Analysis ◽  
Optical Biosensor ◽  
Cationic Porphyrins

Biochemical, biophysical, and thermodynamic analysis of in vitro glycated human serum albumin

2007 ◽  
Vol 72 (2) ◽  
pp. 146-152 ◽  
Author(s):  
Mohd. Wajid Ali Khan ◽  
Zafar Rasheed ◽  
Wahid Ali Khan ◽  
Rashid Ali
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Thermodynamic Analysis

scholarly journals Reaction of the Anticancer Organometallic Ruthenium Compound, [(η6-p-Cymene)Ru(ATSC)Cl]PF6 with Human Serum Albumin

2010 ◽  
Vol 2010 ◽  
pp. 1-7 ◽  
Author(s):  
Floyd A. Beckford
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Thermodynamic Analysis ◽  
Binding Constant ◽  
Enthalpy Of Reaction ◽  
Infrared Spectrophotometry ◽  
Ruthenium Compound ◽  
Different Temperatures ◽  
Entropy Of Reaction

The reaction of [(η6-p-cymene)Ru(ATSC)Cl]PF6 (ATSC =9-anthraldehyde thiosemicarbazone) with human serum albumin was investigated at different temperatures using fluorescence and infrared spectrophotometry. The binding constant, K, for the reaction was determined using a number of different methods. Using a modified Stern-Volmer equation, K was determined to be 9.09×104,12.1×104, and 13.1×104 M−1 at 293 K, 298 K, and 308 K, respectively. A thermodynamic analysis showed that the reaction is spontaneous with ΔG being negative. The enthalpy of reaction ΔH=16.5 kJ mol−1 and the entropy of reaction ΔS=152 Jmol−1K−1. The values of ΔH and ΔS suggest that hydrophobic forces are dominant in the mode of interaction and that the process is mostly entropy driven.

Effect of peripheral platinum(II) bipyridyl complexes on the interaction of tetra-cationic porphyrins with human serum albumin

2020 ◽  
Vol 301 ◽  
pp. 112466 ◽  
Author(s):  
Otávio Augusto Chaves ◽  
Thiago V. Acunha ◽  
Bernardo A. Iglesias ◽  
Catarina S.H. Jesus ◽  
Carlos Serpa
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Cationic Porphyrins
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