Multipoint Analysis of the Rapid Convection Event

2007 ◽  
Vol 50 (5) ◽  
pp. 1100-1106 ◽  
Author(s):  
Yu-Duan MA ◽  
Jin-Bin CAO ◽  
Guo-Cheng ZHOU ◽  
Zhen-Xing LIU ◽  
H. Reme ◽  
...  
Keyword(s):  
Multipoint Analysis

Multipoint Analysis of the Temporal Scale of Bursty Bulk Flow Events during the Quiet Time of Magnetotail

2005 ◽  
Vol 48 (2) ◽  
pp. 277-283 ◽  
Author(s):  
Yu-Duan MA ◽  
Jin-Bin CAO ◽  
Guo-Cheng ZHOU ◽  
Zhen-Xin LIU ◽  
H. Reme ◽  
...  
Keyword(s):  
Temporal Scale ◽  
Bulk Flow ◽  
Quiet Time ◽  
Multipoint Analysis ◽  
Bursty Bulk Flow

A new locus for hemiplegic migraine maps to chromosome 1q31

Neurology ◽  
1997 ◽  
Vol 49 (5) ◽  
pp. 1231-1238 ◽  
Author(s):  
Kathy Gardner ◽  
M. Michael Barmada ◽  
Louis J. Ptacek ◽  
Eric P. Hoffman
Keyword(s):  
Native American ◽  
Autosomal Dominant ◽  
Disease Gene ◽  
Familial Hemiplegic Migraine ◽  
Incomplete Penetrance ◽  
Multipoint Analysis ◽  
Hemiplegic Migraine ◽  
Atypical Symptoms ◽  
Migraine Triggers ◽  
Migrainous Headache

A single familial hemiplegic migraine locus has been previously mapped to 19p13.1 and associated with mutations in a calcium channel gene (CACNL1A4). We describe a new 39-member four-generation family from Wyoming of German-Native American descent with autosomal dominant familial hemiplegic migraine that is not linked to the chromosome 19p locus. Affected individuals showed a stereotypic pattern of migrainous headache associated with hemisensory and hemiparetic attacks, without other headache types. Eighty-three percent reported minor head trauma as a trigger for individual attacks. Seventy-two percent reported other typical migraine triggers for the attacks. Attack frequency decreased with age and the overall course was benign. Genetic linkage studies of this family found strong evidence for the disease gene in this family being located at chromosome 1q31. Multipoint analysis showed lod scores >3 in a 44-cm region flanked by D1S158 and D1S2781, using 80% penetrance and a phenocopy rate of 1/50. Haplotype and multipoint analysis, including flanking markers, suggested incomplete penetrance and variable expressivity of the disease. A single affected patient who reports atypical symptoms including daily headaches likely represents a phenocopy. This new locus for hemiplegic migraine suggests that mutations of additional calcium channels in the region may cause the disease.

Multipoint analysis of quantitative traits

1997 ◽  
Vol 14 (6) ◽  
pp. 845-850 ◽  
Author(s):  
A.J. Marlow ◽  
S. John ◽  
J. Worthington
Keyword(s):  
Quantitative Traits ◽  
Multipoint Analysis
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