Preliminary studies of microencapsulation and anticancer activity of polyphenols extract from Punica granatum peels

2021 ◽  
Author(s):  
Faezeh Fathi ◽  
Samad N. Ebrahimi ◽  
David M. Pereira ◽  
Berta N. Estevinho ◽  
Fernando Rocha
Keyword(s):  
Anticancer Activity ◽  
Punica Granatum

An Insight into Anticancer Bioactives from Punica granatum (Pomegranate)

2021 ◽  
Vol 21 ◽  
Author(s):  
Kanika Sharma ◽  
Payal Kesharwani ◽  
Shiv Kumar Prajapati ◽  
Ankit Jain ◽  
Dolly Jain ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Targeted Delivery ◽  
Punica Granatum ◽  
Pomegranate Juice ◽  
Alternative Source ◽  
M Phase ◽  
Beneficial Impact ◽  
Anticancer Treatment ◽  
The Many ◽  
Pomegranate Peel Extract

: Cancer is one of the major reasons for mortality across the globe. Side effects that are observed with the pharmacological medications present in the market majorly affect the quality of life of patients. This has caused the researchers to find an alternative source of medications such as herbal medicine which has shown a promising effect in anticancer treatment, one such source is Pomegranate, which belongs to the family Punicaceae. Several polyphenols are present in Punica granatum which exhibits properties ranging from antioxidant effect, antidiabetic effect, beneficial impact in treatment, and management of metabolic and cardiovascular disorders to advantageous impact in anticancer treatment. Polyphenols like punicalin, punicalagin, and ellagic acid are a few of the many compounds responsible for the anticancer activity of pomegranate. Many preparations of pomegranate such as Pomegranate Juice (PJ), Pomegranate seed oil (PSO), Pomegranate peel extract (PoPx) etc. are used in various clinical studies. These polyphenols show anticancer activity by either arresting the cell cycle in the G2/M phase, inducing apoptosis, or by damaging the DNA of tumor cells. This review explicitly discusses the role and mechanism of bioactives obtained from the pomegranate in the treatment and management of cancer. The chemical structure, properties and role of pomegranate in the treatment of breast, lung, thyroid, colon, and prostate cancer has been focused in detail. This review also discusses various drug delivery approaches for targeted delivery on tumors as well as patented preparation of pomegranate compounds along with the ongoing clinical trials.

Evaluating Anticancer Activity of Plant-Mediated Synthesized Iron Oxide Nanoparticles Using Punica Granatum Fruit Peel Extract

2020 ◽  
Vol 1204 ◽  
pp. 127539 ◽  
Author(s):  
Mostafa Yusefi ◽  
Kamyar Shameli ◽  
Roshafima Rasit Ali ◽  
Siew-Wai Pang ◽  
Sin-Yeang Teow
Keyword(s):  
Iron Oxide ◽  
Anticancer Activity ◽  
Iron Oxide Nanoparticles ◽  
Punica Granatum ◽  
Oxide Nanoparticles ◽  
Fruit Peel ◽  
Peel Extract

A galactomannan polysaccharide from Punica granatum imparts in vitro and in vivo anticancer activity

2013 ◽  
Vol 98 (2) ◽  
pp. 1466-1475 ◽  
Author(s):  
Manu M. Joseph ◽  
S.R. Aravind ◽  
Suraj K. George ◽  
Sheeja Varghese ◽  
T.T. Sreelekha
Keyword(s):  
Anticancer Activity ◽  
Punica Granatum

Efficacy of Punica granatum extract on in vitro and in vivo control of Trichomonas vaginalis

Planta Medica ◽  
2011 ◽  
Vol 77 (12) ◽  
Author(s):  
GT El Sherbini ◽  
KM Ibrahim ◽  
ET El Sherbini ◽  
NM Abdel Hady ◽  
TA Morsy
Keyword(s):  
Trichomonas Vaginalis ◽  
Punica Granatum

Anticancer activity of resveratrol analogs from Eugenia rigida DC

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
MA Zaki ◽  
V Samoylenko ◽  
S Khan ◽  
RM Abd slam ◽  
MH Hetta ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Resveratrol Analogs

Specific inhbitor of ERK 1/2 AEZS-131: anticancer activity in models of human cancers with and without overactivation of ERK 1/2

2014 ◽  
Vol 74 (S 01) ◽  
Author(s):  
JB Engel ◽  
S Meyer ◽  
J Dietl ◽  
B Kwok ◽  
O Ortmann ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Human Cancers
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