Chiral derivatization for separation of racemic amino and thiol drugs by liquid chromatography and capillary electrophoresis

Chirality ◽  
1995 ◽  
Vol 7 (4) ◽  
pp. 235-242 ◽  
Author(s):  
Pierre Leroy ◽  
Luc Bellucci ◽  
Alain Nicolas
Keyword(s):  
Capillary Electrophoresis ◽  
Liquid Chromatography ◽  
Chiral Derivatization

Sulphonamide: Distribution, Toxicology, Environmental Characteristics, and Analysis - A Review

2020 ◽  
Vol 16 ◽  
Author(s):  
Kirubanandam Grace Pavithra ◽  
Vasudevan Jaikumar ◽  
Ponnusamy Senthil Kumar ◽  
PanneerSelvam SundarRajan
Keyword(s):  
Aqueous Solution ◽  
High Performance Liquid Chromatography ◽  
Capillary Electrophoresis ◽  
Liquid Chromatography ◽  
High Performance ◽  
Uv Spectroscopy ◽  
Relevant Information ◽  
Fluorometric Determination ◽  
Distinctive Features ◽  
The World

Background: Many antibiotics were widely used as medication based on their distinctive features. Among them, sulphonamides were commonly used, however their recalcitrant nature makes them difficult to dispose. Hence, their interaction with environment and analytic technique requires considerable attention globally. Objective: Therefore, this review aimed to provide detailed discussion about environmental as well as human health behaviour and analytic techniques corresponding to sulphonamides. Methods: Various results and discussion were extracted from technical journals and books published by different researchers from all over the world. The cited bibliographic references were intentionally investigated in order to extract relevant information related to proposed work. Results: In this review, the determination techniques such as UV-spectroscopy, Enthalpimetry, Immunosensor, Chromatography, Chemiluminescence, Photoinduced fluorometric determination, Capillary electrophoresis for sulphonamide determination were discussed in detail. Among them, High performance liquid chromatography (HPLC) and UV-spectroscopy was effective and extensively used for screening sulphonamide. Conclusion: Knowing the quantification and behaviour of sulphonamide in aqueous solution is mandatory to opt the suitable wastewater treatment required. Hence, choosing appropriate high precision and feasible screening techniques is necessary, which can be attained with this review.

scholarly journals Single-Run Separation and Quantification of 14 Cannabinoids Using Capillary Electrophoresis

Separations ◽  
2021 ◽  
Vol 8 (3) ◽  
pp. 30
Author(s):  
Emil A. Zaripov ◽  
Tiah Lee ◽  
Yuchu Dou ◽  
Cory S. Harris ◽  
Artem Egorov ◽  
...  
Keyword(s):  
High Pressure ◽  
Capillary Electrophoresis ◽  
Liquid Chromatography ◽  
Sodium Hydroxide ◽  
Limit Of Detection ◽  
Cost Effective ◽  
Uv Detector ◽  
Good Separation ◽  
Method Performance ◽  
Cost Effective Alternative

Quantification of major cannabinoids in cannabis products is normally performed using high-pressure liquid chromatography (HPLC)-based methods. We propose a cost-effective alternative method that successfully separates and quantifies 14 cannabinoids in a single run using capillary electrophoresis (CE) coupled with a UV detector in 18 min. The separation is carried out in 60% acetonitrile in the presence of 6.5 mM sodium hydroxide and 25 µM β-cyclodextrin, resulting in good separation of cannabinoids. Our CE method demonstrated the limit of detection between 1.2–1.8 µg/mL, with the linear range reaching up to 50 µg/mL. We validated the method performance by testing a plant extract and quantifying cannabinoid content. This method is the first to separate 14 cannabinoids in one run using a CE system with UV detection.

Stability-indicating methods for the enantioselective determination of dihydropyridines by high performance liquid chromatography and capillary electrophoresis

2012 ◽  
Vol 4 (9) ◽  
pp. 2953 ◽  
Author(s):  
Alyne Fávero Galvão ◽  
Tatiana Okura Ajimura ◽  
Fernando Armani Aguiar ◽  
Keyller Bastos Borges ◽  
Cristiane Masetto de Gaitani
Keyword(s):  
High Performance Liquid Chromatography ◽  
Capillary Electrophoresis ◽  
Liquid Chromatography ◽  
High Performance ◽  
Stability Indicating
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