Synthesis and enantiomeric purity determination of chiral 3-benzylglycidol, a key synthon for hiv protease inhibitors

Wilfred P. Shum; Jian Chen; Michael J. Cannarsa

doi:10.1002/chir.530060813

Synthesis and enantiomeric purity determination of chiral 3-benzylglycidol, a key synthon for hiv protease inhibitors

Chirality ◽

10.1002/chir.530060813 ◽

1994 ◽

Vol 6 (8) ◽

pp. 681-684 ◽

Cited By ~ 5

Author(s):

Wilfred P. Shum ◽

Jian Chen ◽

Michael J. Cannarsa

Keyword(s):

Protease Inhibitors ◽

Enantiomeric Purity ◽

Hiv Protease ◽

Hiv Protease Inhibitors ◽

Purity Determination

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Simultaneous determination of the HIV protease inhibitors indinavir, amprenavir, saquinavir, ritonavir and nelfinavir in human plasma by high-performance liquid chromatography

Journal of Chromatography B Biomedical Sciences and Applications ◽

10.1016/s0378-4347(00)00617-4 ◽

2001 ◽

Vol 755 (1-2) ◽

pp. 85-89 ◽

Cited By ~ 32

Author(s):

Harumi Yamada ◽

Hajime Kotaki ◽

Tetsuya Nakamura ◽

Aikichi Iwamoto

Keyword(s):

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Simultaneous Determination ◽

Human Plasma ◽

Protease Inhibitors ◽

High Performance ◽

Hiv Protease ◽

Hiv Protease Inhibitors

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Simultaneous determination of HIV-protease inhibitors lamivudine and zidovudine in pharmaceutical formulations by micellar electrokinetic chromatography

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2005.05.002 ◽

2005 ◽

Vol 39 (3-4) ◽

pp. 653-660 ◽

Cited By ~ 15

Author(s):

R. Sekar ◽

S. Azhaguvel

Keyword(s):

Simultaneous Determination ◽

Protease Inhibitors ◽

Micellar Electrokinetic Chromatography ◽

Pharmaceutical Formulations ◽

Hiv Protease ◽

Hiv Protease Inhibitors ◽

Electrokinetic Chromatography

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Simultaneous determination of the HIV-protease inhibitors indinavir, amprenavir, ritonavir, saquinavir and nelfinavir in human plasma by reversed-phase high-performance liquid chromatography

Journal of Chromatography B Biomedical Sciences and Applications ◽

10.1016/s0378-4347(01)00172-4 ◽

2001 ◽

Vol 757 (2) ◽

pp. 325-332 ◽

Cited By ~ 41

Author(s):

Marı́a Sarasa-Nacenta ◽

Yolanda López-Púa ◽

Josep Mallolas ◽

José Luis Blanco ◽

José Mª. Gatell ◽

...

Keyword(s):

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Simultaneous Determination ◽

Human Plasma ◽

Protease Inhibitors ◽

High Performance ◽

Reversed Phase ◽

Hiv Protease ◽

Hiv Protease Inhibitors

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Simultaneous determination of five HIV protease inhibitors nelfinavir, indinavir, ritonavir, saquinavir and amprenavir in human plasma by LC/MS/MS

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/s0731-7085(02)00357-6 ◽

2002 ◽

Vol 30 (3) ◽

pp. 675-684 ◽

Cited By ~ 52

Author(s):

Jingduan Chi ◽

Anura L Jayewardene ◽

Judith A Stone ◽

Toshiro Motoya ◽

Francesca T Aweeka

Keyword(s):

Simultaneous Determination ◽

Human Plasma ◽

Protease Inhibitors ◽

Hiv Protease ◽

Hiv Protease Inhibitors

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Conventional HPLC Method Used for Simultaneous Determination of the Seven HIV Protease Inhibitors and Nonnucleoside Reverse Transcription Inhibitor Efavirenz in Human Plasma

Biological and Pharmaceutical Bulletin ◽

10.1248/bpb.28.1286 ◽

2005 ◽

Vol 28 (7) ◽

pp. 1286-1290 ◽

Cited By ~ 24

Author(s):

Masaaki Takahashi ◽

Masao Yoshida ◽

Tsuyoshi Oki ◽

Naoya Okumura ◽

Tatsuo Suzuki ◽

...

Keyword(s):

Simultaneous Determination ◽

Human Plasma ◽

Protease Inhibitors ◽

Reverse Transcription ◽

Hplc Method ◽

Hiv Protease ◽

Hiv Protease Inhibitors ◽

Transcription Inhibitor

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Simultaneous Determination of the Six HIV Protease Inhibitors (Amprenavir, Indinavir, Lopinavir, Nelfinavir, Ritonavir, and Saquinavir) Plus M8 Nelfinavir Metabolite and the Nonnucleoside Reverse Transcription Inhibitor Efavirenz in Human Plasma by Solid-Phase Extraction and Column Liquid Chromatography

Therapeutic Drug Monitoring ◽

10.1097/00007691-200204000-00012 ◽

2002 ◽

Vol 24 (2) ◽

pp. 302-309 ◽

Cited By ~ 20

Author(s):

Jean-Marie Poirier ◽

Pascal Robidou ◽

Patrice Jaillon

Keyword(s):

Column Liquid Chromatography ◽

Liquid Chromatography ◽

Solid Phase Extraction ◽

Protease Inhibitors ◽

Solid Phase ◽

Hiv Protease ◽

Hiv Protease Inhibitors ◽

Phase Extraction ◽

Transcription Inhibitor

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Simultaneous determination of the HIV-protease inhibitors indinavir, nelfinavir, saquinavir and ritonavir in human plasma by reversed-phase high-performance liquid chromatography

Journal of Chromatography B Biomedical Sciences and Applications ◽

10.1016/s0378-4347(99)00079-1 ◽

1999 ◽

Vol 727 (1-2) ◽

pp. 139-149 ◽

Cited By ~ 87

Author(s):

P.W.H. Hugen ◽

C.P.W.G.M. Verweij-van Wissen ◽

D.M. Burger ◽

E.W. Wuis ◽

P.P. Koopmans ◽

...

Keyword(s):

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Simultaneous Determination ◽

Human Plasma ◽

Protease Inhibitors ◽

High Performance ◽

Reversed Phase ◽

Hiv Protease ◽

Hiv Protease Inhibitors

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Simple and Simultaneous Determination of the HIV-Protease Inhibitors Amprenavir, Atazanavir, Indinavir, Lopinavir, Nelfinavir, Ritonavir and Saquinavir Plus M8 Nelfinavir Metabolite and the Nonnucleoside Reverse Transcriptase Inhibitors Efavirenz and Nevirapine in Human Plasma by Reversed-Phase Liquid Chromatography

Therapeutic Drug Monitoring ◽

10.1097/01.ftd.0000152680.36517.5d ◽

2005 ◽

Vol 27 (2) ◽

pp. 186-192 ◽

Cited By ~ 33

Author(s):

Jean-Marie Poirier ◽

Pascal Robidou ◽

Patrice Jaillon

Keyword(s):

Liquid Chromatography ◽

Protease Inhibitors ◽

Reversed Phase ◽

Hiv Protease ◽

Hiv Protease Inhibitors ◽

Reversed Phase Liquid Chromatography ◽

Reverse Transcriptase Inhibitors ◽

Nonnucleoside Reverse Transcriptase Inhibitors ◽

Phase Liquid

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High-throughput simultaneous determination of the HIV protease inhibitors indinavir and L-756423 in human plasma using semi-automated 96-well solid phase extraction and LC–MS/MS

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/s0731-7085(00)00420-9 ◽

2000 ◽

Vol 24 (2) ◽

pp. 291-305 ◽

Cited By ~ 20

Author(s):

M.J Rose ◽

S.A Merschman ◽

R Eisenhandler ◽

E.J Woolf ◽

K.C Yeh ◽

...

Keyword(s):

Solid Phase Extraction ◽

Simultaneous Determination ◽

Human Plasma ◽

Protease Inhibitors ◽

High Throughput ◽

Solid Phase ◽

Hiv Protease ◽

Hiv Protease Inhibitors ◽

Phase Extraction

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Simultaneous quantitative determination of the HIV protease inhibitors indinavir, amprenavir, ritonavir, lopinavir, saquinavir, nelfinavir and the nelfinavir active metabolite M8 in plasma by liquid chromatography

Journal of Chromatography B ◽

10.1016/s1570-0232(02)00728-6 ◽

2003 ◽

Vol 783 (2) ◽

pp. 491-500 ◽

Cited By ~ 41

Author(s):

U.S Justesen ◽

C Pedersen ◽

N.A Klitgaard

Keyword(s):

Liquid Chromatography ◽

Quantitative Determination ◽

Protease Inhibitors ◽

Active Metabolite ◽

Hiv Protease ◽

Hiv Protease Inhibitors

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