Chiral discrimination by albumin: A mechanistic study of liquid chromatographic optical resolution of nonaromatic carboxylic acids

Chirality ◽  
1993 ◽  
Vol 5 (5) ◽  
pp. 295-299 ◽  
Author(s):  
Stig Allenmark
Keyword(s):  
Carboxylic Acids ◽  
Optical Resolution ◽  
Chiral Discrimination ◽  
Mechanistic Study ◽  
Liquid Chromatographic

Preparation of chiral stationary phase via activated carbamate intermediate for liquid chromatographic optical resolution

1987 ◽  
Vol 23 (10) ◽  
pp. 727-730 ◽  
Author(s):  
K. Iwaki ◽  
S. Yoshida ◽  
N. Nimura ◽  
T. Kinoshita ◽  
K. Takeda ◽  
...  
Keyword(s):  
Stationary Phase ◽  
Chiral Stationary Phase ◽  
Optical Resolution ◽  
Liquid Chromatographic

scholarly journals Liquid Chromatographic Investigation of Spontaneous Oscillatory In Vitro Chiral Conversion and Spontaneous Oscillatory Condensation of Simple Carboxylic Acids in Aqueous and Nonaqueous Media

2011 ◽  
Vol 2011 ◽  
pp. 1-11
Author(s):  
Mieczyslaw Sajewicz ◽  
Teresa Kowalska
Keyword(s):  
Carboxylic Acids ◽  
Small Contribution ◽  
Nonaqueous Media ◽  
Analytical Technique ◽  
Oxidation Reduction ◽  
Oscillatory Reactions ◽  
Liquid Chromatographic ◽  
Chromatographic Evidence ◽  
Organic Oxidation

Oscillatory reactions are a narrow reaction type among the entity of chemical reactions and those involving purely organic compounds make a small contribution to an overall number of all known oscillatory reactions. The most abundant type is purely inorganic and mixed inorganic-organic oxidation-reduction reactions, basically because monitoring them is relatively easy (e.g., with use of potentiometric measurements). Investigation of the organic reactions can be more demanding, and then chromatography is an analytical technique of choice. In this paper, we provide an overview of chromatographic evidence with oscillatory reactions discovered in our laboratory in the course of the last several years that involve the low-molecular-weight carboxylic acids (profen drugs, amino acids, and hydroxy acids). The investigated processes comprise the oscillatory chiral conversion and the oscillatory condensation, spontaneously running in the aqueous and nonaqueous abiotic media, and they were traced with use of TLC and HPLC coupled with different detector types.

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