Comparative study of different chiral ligands for dynamic kinetic resolution of amino acids

Chirality ◽  
2021 ◽  
Vol 33 (10) ◽  
pp. 685-702
Author(s):  
Keita Nagaoka ◽  
Arina Nakano ◽  
Jianlin Han ◽  
Tsubasa Sakamoto ◽  
Hiroyuki Konno ◽  
...  
Keyword(s):  
Amino Acids ◽  
Comparative Study ◽  
Kinetic Resolution ◽  
Chiral Ligands ◽  
Dynamic Kinetic Resolution

scholarly journals Recyclable and Stable α-Methylproline-Derived Chiral Ligands for the Chemical Dynamic Kinetic Resolution of free C,N-Unprotected α-Amino Acids

Molecules ◽  
2019 ◽  
Vol 24 (12) ◽  
pp. 2218
Author(s):  
Shuangjie Shu ◽  
Liang Zhao ◽  
Shengbin Zhou ◽  
Chenglin Wu ◽  
Hong Liu ◽  
...  
Keyword(s):  
Amino Acids ◽  
Schiff Base ◽  
Kinetic Resolution ◽  
Chiral Ligands ◽  
Chiral Ligand ◽  
Quaternary Carbon ◽  
Dynamic Kinetic Resolution ◽  
High Yields

A novel special designed, stable, and recyclable chiral ligand bearing a quaternary carbon was developed for chemical dynamic kinetic resolution (DKR) of free C,N-unprotected racemic α-amino acids via Schiff base intermediates. This method furnishes high yields with excellent enantioselectivity, has a broad substrate scope, and uses operationally simple and convenient conditions. The present chemical DKR is a practical and useful method for the preparation of enantiopure α-amino acids.

Stereoselective Synthesis ofanti-β-Hydroxy-α-amino Acids through Dynamic Kinetic Resolution

2004 ◽  
Vol 116 (7) ◽  
pp. 900-902 ◽  
Author(s):  
Kazuishi Makino ◽  
Takayuki Goto ◽  
Yasuhiro Hiroki ◽  
Yasumasa Hamada
Keyword(s):  
Amino Acids ◽  
Kinetic Resolution ◽  
Stereoselective Synthesis ◽  
Dynamic Kinetic Resolution

Recyclable Ligands for the Non-Enzymatic Dynamic Kinetic Resolution of Challenging α-Amino Acids

2015 ◽  
Vol 54 (44) ◽  
pp. 12918-12922 ◽  
Author(s):  
Yong Nian ◽  
Jiang Wang ◽  
Shengbin Zhou ◽  
Shuni Wang ◽  
Hiroki Moriwaki ◽  
...  
Keyword(s):  
Amino Acids ◽  
Kinetic Resolution ◽  
Dynamic Kinetic Resolution

Enzymatic Dynamic Kinetic Resolution of Oxazinones: A New Approach to Enantiopure β2-Amino Acids

ChemCatChem ◽  
2011 ◽  
Vol 3 (2) ◽  
pp. 319-330 ◽  
Author(s):  
Albrecht Berkessel ◽  
Ilona Jurkiewicz ◽  
Resmi Mohan
Keyword(s):  
Amino Acids ◽  
Kinetic Resolution ◽  
Dynamic Kinetic Resolution ◽  
New Approach

Stereoselective Synthesis ofanti-β-Hydroxy-α-amino Acids through Dynamic Kinetic Resolution

2004 ◽  
Vol 43 (7) ◽  
pp. 882-884 ◽  
Author(s):  
Kazuishi Makino ◽  
Takayuki Goto ◽  
Yasuhiro Hiroki ◽  
Yasumasa Hamada
Keyword(s):  
Amino Acids ◽  
Kinetic Resolution ◽  
Stereoselective Synthesis ◽  
Dynamic Kinetic Resolution

scholarly journals New Enzymatic Method of Chiral Amino Acid Synthesis by Dynamic Kinetic Resolution of Amino Acid Amides: Use of Stereoselective Amino Acid Amidases in the Presence of α-Amino-ε-Caprolactam Racemase

2007 ◽  
Vol 73 (16) ◽  
pp. 5370-5373 ◽  
Author(s):  
Shigenori Yamaguchi ◽  
Hidenobu Komeda ◽  
Yasuhisa Asano
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Kinetic Resolution ◽  
Acid Synthesis ◽  
Enzymatic Method ◽  
Ochrobactrum Anthropi ◽  
Dynamic Kinetic Resolution ◽  
Amino Acid Synthesis

ABSTRACT d- and l-amino acids were produced from l- and d-amino acid amides by d-aminopeptidase from Ochrobactrum anthropi C1-38 and l-amino acid amidase from Pseudomonas azotoformans IAM 1603, respectively, in the presence of α-amino-ε-caprolactam racemase from Achromobacter obae as the catalyst by dynamic kinetic resolution of amino acid amides.

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