Selecting Resolving Agents with Respect to Their Eutectic Compositions

Chirality ◽  
2016 ◽  
Vol 28 (3) ◽  
pp. 230-234 ◽  
Author(s):  
Zsolt Szeleczky ◽  
Sándor Semsey ◽  
Péter Bagi ◽  
Emese Pálovics ◽  
Ferenc Faigl ◽  
...  
Keyword(s):  
Resolving Agents

Enantiomeric impurities in chiral catalysts, auxiliaries, synthons and resolving agents. Part 2

1999 ◽  
Vol 10 (1) ◽  
pp. 37-60 ◽  
Author(s):  
Daniel W Armstrong ◽  
Lingfeng He ◽  
Timothy Yu ◽  
Jauh T Lee ◽  
Yan-song Liu
Keyword(s):  
Chiral Catalysts ◽  
Resolving Agents

scholarly journals Microwave-Assisted Synthesis of(±)-Mandelic Acid-d5, Optical Resolution, and Absolute Configuration Determination

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Claudio Bruno ◽  
Giovanni Lentini ◽  
Angelo Lovece ◽  
Maria Maddalena Cavalluzzi ◽  
Alessia Carocci ◽  
...  
Keyword(s):  
Capillary Electrophoresis ◽  
Mandelic Acid ◽  
Optical Resolution ◽  
Racemic Mixture ◽  
Microwave Assisted Synthesis ◽  
Salt Formation ◽  
Microwave Assisted ◽  
Diastereomeric Salts ◽  
Chiral Capillary Electrophoresis ◽  
Resolving Agents

An efficient microwave-assisted synthesis of(±)-mandelic acid-d5was developed. The racemic mixture was resolved by diastereomeric salt formation using 1-phenylethylamine enantiomers as resolving agents. At each step, the resolution process was checked by determining mandelic acid-d5enantiomer ee values directly on fractional crystallized diastereomeric salts by chiral capillary electrophoresis analysis. Highly enriched (−)- and (+)-mandelic acid-d5(95% and 90% ee, resp.) were obtained and their absolute configurations—RandS, respectively—were determined by correlation of the (−)-mandelic acid-d5circular dichroism spectrum to the (R)-mandelic acid one.

Enantiomers of (2R∗,3R∗)-1-methyl-5-oxo-2-phenyltetrahydro-1H-pyrrolidine-3-carboxylic acid as novel chiral resolving agents

2008 ◽  
Vol 19 (3) ◽  
pp. 309-317 ◽  
Author(s):  
Katarzyna Piwowarczyk ◽  
Anna Zawadzka ◽  
Piotr Roszkowski ◽  
Joanna Szawkało ◽  
Andrzej Leniewski ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Resolving Agents

Towards a rational design of resolving agents. Part III. structural study of two pairs of diastereomeric salts of ephedrine and a cyclic phosphoric acid

2010 ◽  
Vol 110 (1) ◽  
pp. 13-18 ◽  
Author(s):  
F. J. J. Leusen ◽  
H. J. Bruins Slot ◽  
J. H. Noordik ◽  
A. D. van der Haest ◽  
H. Wynberg ◽  
...  
Keyword(s):  
Phosphoric Acid ◽  
Structural Study ◽  
Rational Design ◽  
Diastereomeric Salts ◽  
Resolving Agents
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