ChemInform Abstract: Isoxazolo[4,3-e]indazole as a New Heterocyclic System: Design, Synthesis, Spectroscopic Characterization, and Antibacterial Activity.

ChemInform ◽  
2016 ◽  
Vol 47 (29) ◽  
Author(s):  
Masoumeh Ghaemi ◽  
Mehdi Pordel
Keyword(s):  
Antibacterial Activity ◽  
System Design ◽  
Heterocyclic System ◽  
Spectroscopic Characterization ◽  
Design Synthesis

Design, Synthesis and Docking Studies of Some Novel Fluoroquinolone Compounds with Antibacterial Activity

2018 ◽  
Vol 69 (4) ◽  
pp. 815-822 ◽  
Author(s):  
Lucia Pintilie ◽  
Amalia Stefaniu ◽  
Alina Ioana Nicu ◽  
Maria Maganu ◽  
Miron Teodor Caproiu
Keyword(s):  
Antimicrobial Activity ◽  
Antibacterial Activity ◽  
Molecular Docking ◽  
Drug Discovery ◽  
Elemental Analysis ◽  
Docking Studies ◽  
Receptor Protein ◽  
Chemical Methods ◽  
Design Synthesis ◽  
Gram Negative

A new series of fluoroquinolone compounds have been obtained by Gould-Jacobs method. The compounds have been characterized by physic-chemical methods (elemental analysis, FTIR, NMR, UV-Vis) and by antimicrobial activity against Gram-positive and Gram-negative microorganisms. For the synthesized compounds have been performed calculations of characteristics and molecular properties, using Spartan�14 Software from Wavefunction, Inc. Irvine, CA. and molecular docking studies using CLC Drug Discovery Workbench 2.4 software, to identify and visualize the most likely interaction ligand (fluoroquinolone) with the receptor protein.

Novel thiobarbiturates as potent urease inhibitors with potential antibacterial activity: Design, synthesis, radiolabeling and biodistribution study

2020 ◽  
Vol 28 (23) ◽  
pp. 115759
Author(s):  
Hanan Gaber Abdulwahab ◽  
Marwa F. Harras ◽  
Nagwan Galal El Menofy ◽  
Amany M. Hegab ◽  
Basma M. Essa ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Biodistribution Study ◽  
Urease Inhibitors ◽  
Design Synthesis ◽  
Activity Design

Design, Synthesis and Structure of Novel Para-Quinones and their Antibacterial Activity

2011 ◽  
Vol 78 (5) ◽  
pp. 787-799 ◽  
Author(s):  
Komala Pandurangan ◽  
Kevin D. Murnaghan ◽  
Aurora Walshe ◽  
Helge Müller-Bunz ◽  
Francesca Paradisi ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Design Synthesis

Trickle System Design Synthesis

1990 ◽  
pp. 582-602
Author(s):  
Jack Keller ◽  
Ron D. Bliesner
Keyword(s):  
System Design ◽  
Design Synthesis
Sign in / Sign up

Export Citation Format

Share Document