ChemInform Abstract: Diastereoselective Synthesis of trans-3,5-Disubstituted Dihydrofuran-2(3H)-ones via SmI2-Mediated Reductive Coupling of 2-Alkylacrylates of N,N-Diisopropyl-2-hydroxybenzamide with Aldehydes.

ChemInform ◽  
2016 ◽  
Vol 47 (22) ◽  
Author(s):  
Yecai Lai ◽  
Lijie Sun ◽  
Man Ki Sit ◽  
Yan Wang ◽  
Wei-Min Dai
Keyword(s):  
Reductive Coupling ◽  
Diastereoselective Synthesis

Diastereoselective synthesis of 1,2-diphenyl-1,2-diaminoethanes by Yb(OTf)3 accelerated reductive coupling of imines

1998 ◽  
Vol 39 (20) ◽  
pp. 3333-3336 ◽  
Author(s):  
Rita Annunziata ◽  
Maurizio Benaglia ◽  
Mauro Cinquini ◽  
Franco Cozzi ◽  
Laura Raimondi
Keyword(s):  
Reductive Coupling ◽  
Diastereoselective Synthesis

ChemInform Abstract: Diastereoselective Synthesis of 1,2-Diphenyl-1,2-diaminoethanes by Yb(OTf)3 Accelerated Reductive Coupling of Imines.

ChemInform ◽  
2010 ◽  
Vol 29 (33) ◽  
pp. no-no
Author(s):  
R. ANNUNZIATA ◽  
M. BENAGLIA ◽  
M. CINQUINI ◽  
F. COZZI ◽  
L. RAIMONDI
Keyword(s):  
Reductive Coupling ◽  
Diastereoselective Synthesis

Naturally Occurring Organic Acid-catalyzed Facile Diastereoselective Synthesis of Biologically Active (E)-3-(arylimino)indolin-2-one Derivatives in Water at Room Temperature

2019 ◽  
Vol 23 (16) ◽  
pp. 1778-1788 ◽  
Author(s):  
Gurpreet Kaur ◽  
Arvind Singh ◽  
Kiran Bala ◽  
Mamta Devi ◽  
Anjana Kumari ◽  
...  
Keyword(s):  
Room Temperature ◽  
Biologically Active ◽  
Environmentally Benign ◽  
Diastereoselective Synthesis ◽  
Substituted Anilines ◽  
Reaction Conditions ◽  
Naturally Occurring ◽  
Acid Catalyzed ◽  
Reaction Media ◽  
Column Chromatographic

A simple, straightforward and efficient method has been developed for the synthesis of (E)-3-(arylimino)indolin-2-one derivatives and (E)-2-((4-methoxyphenyl)imino)- acenaphthylen-1(2H)-one. The synthesis of these biologically-significant scaffolds was achieved from the reactions of various substituted anilines and isatins or acenaphthaquinone, respectively, using commercially available, environmentally benign and naturally occurring organic acids such as mandelic acid or itaconic acid as catalyst in aqueous medium at room temperature. Mild reaction conditions, energy efficiency, good to excellent yields, environmentally benign conditions, easy isolation of products, no need of column chromatographic separation and the reusability of reaction media are some of the significant features of the present protocol.

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