ChemInform Abstract: Stereoselective Synthesis of Alkyl Styryl Selenides in One-Pot: A Straightforward Approach by in situ Dialkyl Diselenide Formation under Transition Metal-Free Conditions.

ChemInform ◽  
2016 ◽  
Vol 47 (19) ◽  
Author(s):  
Adrian A. Heredia ◽  
Alicia B. Penenory
Keyword(s):  
Transition Metal ◽  
Stereoselective Synthesis ◽  
One Pot ◽  
Metal Free ◽  
Straightforward Approach

Stereoselective synthesis of alkyl styryl selenides in one-pot: a straightforward approach by in situ dialkyl diselenide formation under transition metal-free conditions

RSC Advances ◽  
2015 ◽  
Vol 5 (128) ◽  
pp. 105699-105706 ◽  
Author(s):  
Adrián A. Heredia ◽  
Alicia B. Peñéñory
Keyword(s):  
Transition Metal ◽  
Stereoselective Synthesis ◽  
One Pot ◽  
Metal Free ◽  
One Pot Synthesis ◽  
Straightforward Approach

One-pot synthesis of alkyl styryl selenides using KSeCN as selenium source.

Iodine-promoted one pot reaction of pyridin-2-amine with arylmethyl ketone and selenosulfonate: synthesis of 3-(alkylselanyl)-2-arylimidazo[1,2-a]pyridine under transition-metal free conditions

2019 ◽  
Vol 6 (5) ◽  
pp. 654-659 ◽  
Author(s):  
Nan Jiang ◽  
Yi Fang ◽  
Yue Fang ◽  
Shun-Yi Wang ◽  
Shun-Jun Ji
Keyword(s):  
Transition Metal ◽  
One Pot ◽  
Metal Free ◽  
Efficient Approach

A new efficient approach for the I2 promoted selenium functionalization of in situ generated imidazoheterocycles utilizing aliphatic selenosulfonate as the selenium source under transition metal-free conditions is developed.

scholarly journals Transition Metal-Free Synthesis of Halobenzo[b]furans from O-Aryl Carbamates via o-Lithiation Reactions

Molecules ◽  
2022 ◽  
Vol 27 (2) ◽  
pp. 525
Author(s):  
Claudia Feberero ◽  
Cintia Virumbrales ◽  
Carlos Sedano ◽  
Lorena Renedo ◽  
Samuel Suárez-Pantiga ◽  
...  
Keyword(s):  
Transition Metal ◽  
Microwave Irradiation ◽  
Alkaline Hydrolysis ◽  
Fine Tuning ◽  
Conventional Heating ◽  
One Pot ◽  
Metal Free ◽  
Electrophilic Reagents

A straightforward and transition metal-free one-pot protocol to synthesize halobenzo[b]furans has been developed employing simple and easily available starting materials such as O-aryl carbamates and alkynylsulfones. The fine-tuning of the different steps involved was key to achieving a successful one-pot procedure. Initially, a directed ortho-lithiation process, which uses the carbamate as the directed metalation group, was crucial in providing access to O-2-alkynylaryl N,N-diethyl carbamates by a direct alkynylation of the o-lithiated carbamate, with arylsulfonylalkynes as electrophilic reagents. Cyclization of the generated o-alkynylaryl carbamates was successfully accomplished through a strategy involving in situ carbamate alkaline hydrolysis under conventional heating or microwave irradiation, coupled with a subsequent heterocyclization step delivering the desired benzo[b]furans. A wide variety of new halobenzo[b]furans has been synthesized and their utility has been demonstrated by their further transformation.

Construction of multiple bonds via a domino reaction of trifluoroacetimidoyl nitriles with in situ generated bis-nucleophiles

2020 ◽  
Vol 56 (59) ◽  
pp. 8222-8225
Author(s):  
Deng-Yuan Li ◽  
Jia-Yan Chen ◽  
Da-Fu Feng ◽  
Shuang Chen ◽  
Xian-Kuan Xu ◽  
...  
Keyword(s):  
Transition Metal ◽  
Domino Reaction ◽  
Multiple Bonds ◽  
One Pot ◽  
Metal Free ◽  
The One

A transition-metal-free double addition/double rearrangement domino reaction affording CF3-substituted pyrimidines was developed, which enables the one-pot construction of five new bonds, namely three C–C bonds and two C–N bonds.

scholarly journals An entry to 2-(cyclobut-1-en-1-yl)-1H-indoles through a cyclobutenylation/deprotection cascade

2021 ◽  
Author(s):  
Philipp Natho ◽  
Zeyu Yang ◽  
Lewis Allen ◽  
Juliette Rey ◽  
Andrew J P White ◽  
...  
Keyword(s):  
Transition Metal ◽  
One Pot ◽  
Metal Free ◽  
Mild Conditions

A transition-metal-free strategy for the synthesis of 2-(cyclobut-1-en-1-yl)-1H-indoles under mild conditions is described herein. A series of substituted 2-(cyclobut-1-en-1-yl)-1H-indoles are accessed by a one-pot cyclobutenylation/deprotection cascade from N-Boc protected indoles....

Insertion Reaction of 2-Halo-N-allylanilines with K2S Involving Trisulfur Radical Anion: Synthesis of Benzothiazole Derivatives under Transition-Metal-Free Conditions

Synthesis ◽  
2020 ◽  
Author(s):  
Yan-Wei Zhao ◽  
Shun-Yi Wang ◽  
Xin-Yu Liu ◽  
Tian Jiang ◽  
Weidong Rao
Keyword(s):  
Transition Metal ◽  
Radical Anion ◽  
Radical Cyclization ◽  
Transition Metal Catalysis ◽  
Insertion Reaction ◽  
Metal Catalysis ◽  
Metal Free ◽  
Benzothiazole Derivatives

AbstractA synthesis of benzothiazole derivatives through the reaction of 2-halo-N-allylanilines with K2S in DMF is developed. The trisulfur radical anion S3·–, which is generated in situ from K2S in DMF, initiates the reaction without transition-metal catalysis or other additives. In addition, two C–S bonds are formed and heteroaromatization of benzothiazole is triggered by radical cyclization and H-shift.

ChemInform Abstract: Transition Metal Free Intramolecular S-Arylation: One-Pot Synthesis of Thiochromen-4-ones.

ChemInform ◽  
2014 ◽  
Vol 45 (13) ◽  
pp. no-no
Author(s):  
T. A. Jenifer Vijay ◽  
Kebbahalli N. Nandeesh ◽  
Goravanahalli M. Raghavendra ◽  
Kanchugarakoppal S. Rangappa ◽  
Kempegowda Mantelingu
Keyword(s):  
Transition Metal ◽  
One Pot ◽  
Metal Free ◽  
One Pot Synthesis
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