ChemInform Abstract: A Novel Synthesis of Some 1,4-Phenylene-bis-heterocyclic Derivatives and of Some Pyran, Pyrano[2,3-c]pyrazole, and Pyrano[2,3-d]pyrimidine Derivatives.

ChemInform ◽  
2015 ◽  
Vol 46 (49) ◽  
pp. no-no
Author(s):  
F. M. Abdelrazek ◽  
M. H. Helal ◽  
A. S. Hebishy ◽  
S. M. Hassan
Keyword(s):  
Pyrimidine Derivatives ◽  
Novel Synthesis ◽  
Heterocyclic Derivatives

Heterocyclic Synthesis with Nitriles: A Novel Synthesis of Some Thiophene and Thieno[2,3-d]pyrimidine Derivatives, II [1]

1989 ◽  
Vol 44 (4) ◽  
pp. 488-492 ◽  
Author(s):  
Fathy Mohamed Abdelrazek
Keyword(s):  
Heterocyclic Synthesis ◽  
Pyrimidine Derivatives ◽  
Novel Synthesis ◽  
Thiophene Derivatives

Some differently substituted 4-phenylthiophene derivatives 2a-d and 8a, b have been prepared from α-substituted-β-thiocyanatomethyl cinnamonitrile (1). The thiophene derivatives 2a, b and 8a react with trichloroacetonitrile and formamide to afford thieno[2,3-d]pyrimidine derivatives 4, 5 a-c, 7 and 9 a-c, respectively.

scholarly journals 1,1’-(3-Methyl-4-phenylthieno[2,3-b]thiophene-2,5-diyl)diethanone as a Building Block in Heterocyclic Synthesis. Novel Synthesis of Some Pyrazole and Pyrimidine Derivatives

Molecules ◽  
2011 ◽  
Vol 16 (8) ◽  
pp. 6502-6511 ◽  
Author(s):  
Yahia Nasser Mabkhot ◽  
Abdullah Mohammed Al-Majid ◽  
Assem Barakat ◽  
Saeed Alshahrani ◽  
Yamin Siddiqui
Keyword(s):  
Building Block ◽  
Heterocyclic Synthesis ◽  
Pyrimidine Derivatives ◽  
Novel Synthesis

Enaminonitriles in Heterocyclic Synthesis: Novel Synthesis of 3-Aminopyrroles and Pyrrolo[3,2-d]pyrimidine Derivatives

2008 ◽  
Vol 63 (5) ◽  
pp. 564-570 ◽  
Author(s):  
Abdellatif M. Salaheldin
Keyword(s):  
Heterocyclic Synthesis ◽  
Pyrimidine Derivatives ◽  
Novel Synthesis ◽  
Substituted Pyrroles

Several new 3-aminopyrrole derivatives have been synthesized from 3-substituted amino-2-phenylacrylonitriles using Thorpe-Ziegler cyclization. These substituted pyrroles are readily converted into 5H-pyrrolo[3,2-d]pyrimidines (9-deazapurines).

scholarly journals SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF NOVEL PYRAZOLO[3,4-b]PYRIDINES AND THEIR SPIRO-HETEROCYCLIC DERIVATIVES

2014 ◽  
Vol 10 (7) ◽  
pp. 2901-2915 ◽  
Author(s):  
Shawkat A. Abdelmohsen ◽  
Talaat I El Emary
Keyword(s):  
Antimicrobial Activity ◽  
Aromatic Aldehydes ◽  
Antibacterial And Antifungal Activity ◽  
Pyrimidine Derivatives ◽  
Spiro Derivatives ◽  
Heterocyclic Derivatives ◽  
Bacteria And Fungi ◽  
Antibacterial And Antifungal ◽  
New Compounds ◽  
Hydrazone Derivative

The present work describes the synthesis of a novel series of heterocyclic moieties derived from 5-acetylpyrazolo[3,4-b]pyridine (1). The formation of chalcones (2a-d) was utilized to synthesize pyrazoline, isoxazoline and pyrimidine derivatives (3-10). Thiosemicarbazone and semicarbazone (11, 17) were utilized to synthesize other new triazolethiones, thiadiazole and selenadiazole derivatives (11-19). Some new spiro derivatives (22-25) were synthesized by the reaction of chalcone (21) of 1 and isatine with hydrazines, hydroxyl amines and thiourea. Also, The reaction of 1 with cyanoacetyl hydrazine gave the hydrazide-hydrazone derivative 26, which was allowed to react with aromatic aldehydes and α-cyanocinnamonitrile to afford coumarine and substituted pyridine derivatives (28, 29). The structures of all the new compounds have been established on the basis of their analytical and spectral data. Twenty two of the synthesized compounds were also evaluated for their antibacterial and antifungal activity against various strains of bacteria and fungi and most are found to possess promising antimicrobial activity when compared with Chloramphenicol and Clotrimazole

ChemInform Abstract: A Novel Synthesis of Pyrano(2,3-d)pyrimidine Derivatives

ChemInform ◽  
2010 ◽  
Vol 26 (37) ◽  
pp. no-no
Author(s):  
J. M. QUINTELA ◽  
C. PEINADOR ◽  
M. J. MOREIRA
Keyword(s):  
Pyrimidine Derivatives ◽  
Novel Synthesis

Pyrimidine derivatives and related compounds VI. A novel synthesis of 3,5-diacetamidopyrazole and of 2-aminopyrazolo [1,5-α] pyrimidines

1977 ◽  
Vol 14 (1) ◽  
pp. 155-158 ◽  
Author(s):  
Mohamed Hilmy Fanagdi ◽  
Ezzat Mohamed Kandeel ◽  
Ezzat Mohamed Zayed ◽  
Zaghtoul Flshahat Kandil
Keyword(s):  
Pyrimidine Derivatives ◽  
Novel Synthesis ◽  
Related Compounds

A novel synthesis of flourinated pyrido [2,3-d] pyrimidine derivatives

1988 ◽  
Vol 41 (3) ◽  
pp. 303-310 ◽  
Author(s):  
L. Prakash ◽  
S.S. Verma ◽  
Shaihla ◽  
Erra Tyagi ◽  
R.L. Mital
Keyword(s):  
Pyrimidine Derivatives ◽  
Novel Synthesis
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