ChemInform Abstract: EGFR/HER-2 Inhibitors: Synthesis, Biological Evaluation and 3D-QSAR Analysis of Dihydropyridine-Containing Thiazolinone Derivatives.

Yu-Jia Ren; Zhong-Chang Wang; Xin Zhang; Han-Yue Qiu; Peng-Fei Wang; Hai-Bin Gong; Ai-Qin Jiang; Hai-Liang Zhu

doi:10.1002/chin.201530200

ChemInform Abstract: EGFR/HER-2 Inhibitors: Synthesis, Biological Evaluation and 3D-QSAR Analysis of Dihydropyridine-Containing Thiazolinone Derivatives.

ChemInform ◽

10.1002/chin.201530200 ◽

2015 ◽

Vol 46 (30) ◽

pp. no-no

Author(s):

Yu-Jia Ren ◽

Zhong-Chang Wang ◽

Xin Zhang ◽

Han-Yue Qiu ◽

Peng-Fei Wang ◽

...

Keyword(s):

3D Qsar ◽

Biological Evaluation ◽

Qsar Analysis ◽

Her 2

Download Full-text

EGFR/HER-2 inhibitors: synthesis, biological evaluation and 3D-QSAR analysis of dihydropyridine-containing thiazolinone derivatives

RSC Advances ◽

10.1039/c4ra10606g ◽

2015 ◽

Vol 5 (28) ◽

pp. 21445-21454 ◽

Cited By ~ 5

Author(s):

Yu-Jia Ren ◽

Zhong-Chang Wang ◽

Xin Zhang ◽

Han-Yue Qiu ◽

Peng-Fei Wang ◽

...

Keyword(s):

Tumor Cell ◽

Kinase Inhibitors ◽

Biological Activities ◽

3D Qsar ◽

Biological Evaluation ◽

Qsar Analysis ◽

Her 2

A series of dihydropyridin containing thiazolinone derivatives (4a–4r) have been designed, synthesized and their biological activities were also evaluated as potential EGFR and HER-2 kinase inhibitors and tumor cell antiproliferation.

Download Full-text

Design, synthesis, biological evaluation, and 3D-QSAR analysis of podophyllotoxin-dioxazole combination as tubulin targeting anticancer agents

Chemical Biology & Drug Design ◽

10.1111/cbdd.12942 ◽

2017 ◽

Vol 90 (2) ◽

pp. 236-243 ◽

Cited By ~ 7

Author(s):

Zi-Zhen Wang ◽

Wen-Xue Sun ◽

Xue Wang ◽

Ya-Han Zhang ◽

Han-Yue Qiu ◽

...

Keyword(s):

Anticancer Agents ◽

3D Qsar ◽

Biological Evaluation ◽

Design Synthesis ◽

Qsar Analysis

Download Full-text

Design, biological evaluation and 3D QSAR studies of novel dioxin-containing pyrazoline derivatives with thiourea skeleton as selective HER-2 inhibitors

Scientific Reports ◽

10.1038/srep27571 ◽

2016 ◽

Vol 6 (1) ◽

Cited By ~ 5

Author(s):

Bing Yang ◽

Yu-Shun Yang ◽

Na Yang ◽

Guigen Li ◽

Hai-Liang Zhu

Keyword(s):

3D Qsar ◽

Biological Evaluation ◽

Qsar Studies ◽

Her 2

Download Full-text

Aldose reductase inhibitors for diabetic complications: Receptor induced atom-based 3D-QSAR analysis, synthesis and biological evaluation

Journal of Molecular Graphics and Modelling ◽

10.1016/j.jmgm.2015.03.005 ◽

2015 ◽

Vol 59 ◽

pp. 59-71 ◽

Cited By ~ 8

Author(s):

Bhawna Vyas ◽

Manjinder Singh ◽

Maninder Kaur ◽

Malkeet Singh Bahia ◽

Amteshwar Singh Jaggi ◽

...

Keyword(s):

Aldose Reductase ◽

Diabetic Complications ◽

3D Qsar ◽

Biological Evaluation ◽

Qsar Analysis ◽

Aldose Reductase Inhibitors ◽

Reductase Inhibitors ◽

Synthesis And Biological Evaluation

Download Full-text

Synthesis, 3D-QSAR analysis and biological evaluation of quinoxaline 1,4-di-N-oxide derivatives as antituberculosis agents

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2016.01.066 ◽

2016 ◽

Vol 26 (16) ◽

pp. 4146-4153 ◽

Cited By ~ 12

Author(s):

Yuanhu Pan ◽

Panpan Li ◽

Shuyu Xie ◽

Yanfei Tao ◽

Dongmei Chen ◽

...

Keyword(s):

3D Qsar ◽

Biological Evaluation ◽

Qsar Analysis

Download Full-text

Green synthesis, biological evaluation, molecular docking studies and 3D-QSAR analysis of novel phenylalanine linked quinazoline-4(3H)-one-sulphonamide hybrid entities distorting the malarial reductase activity in folate pathway

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2019.06.038 ◽

2019 ◽

Vol 27 (16) ◽

pp. 3574-3586 ◽

Cited By ~ 4

Author(s):

Tarosh S. Patel ◽

Jaimin D. Bhatt ◽

Ritu B. Dixit ◽

Chaitanya J. Chudasama ◽

Bhavesh D. Patel ◽

...

Keyword(s):

Molecular Docking ◽

Green Synthesis ◽

Reductase Activity ◽

3D Qsar ◽

Docking Studies ◽

Biological Evaluation ◽

Molecular Docking Studies ◽

Qsar Analysis ◽

Folate Pathway

Download Full-text

3D-QSAR Analysis and Molecular Docking Studies on 3-Arylcoumarin Derivatives as Potential α- Glucosidase Inhibitors

10.37421/mccr.2020.10.548 ◽

2020 ◽

Vol 10 (6) ◽

Author(s):

Gupta K ◽

Tuteja JS

Keyword(s):

Molecular Docking ◽

3D Qsar ◽

Docking Studies ◽

Molecular Docking Studies ◽

Qsar Analysis ◽

Glucosidase Inhibitors

Download Full-text

3D-QSAR Analysis on N-Phenylacetanoyl-L-Homoserine Lactones as Inhibitors of Bacterial Quorum Sensing via CoMFA Approach

Letters in Drug Design & Discovery ◽

10.2174/157018008785909831 ◽

2008 ◽

Vol 5 (7) ◽

pp. 449-453

Author(s):

Ping-Hua Sun ◽

Zhao-Qi Yang ◽

Wei-Min Chen ◽

Qian Liu ◽

Xin-Sheng Yao

Keyword(s):

Quorum Sensing ◽

3D Qsar ◽

Homoserine Lactones ◽

Qsar Analysis ◽

Bacterial Quorum Sensing ◽

Bacterial Quorum

Download Full-text

Integrated Computational Tools for Identification of CCR5 Antagonists as Potential HIV-1 Entry Inhibitors: Homology Modeling, Virtual Screening, Molecular Dynamics Simulations and 3D QSAR Analysis

Molecules ◽

10.3390/molecules19045243 ◽

2014 ◽

Vol 19 (4) ◽

pp. 5243-5265 ◽

Cited By ~ 7

Author(s):

Suri Moonsamy ◽

Radha Dash ◽

Mahmoud Soliman

Keyword(s):

Molecular Dynamics ◽

Virtual Screening ◽

Homology Modeling ◽

3D Qsar ◽

Computational Tools ◽

Qsar Analysis ◽

Entry Inhibitors ◽

Ccr5 Antagonists ◽

Dynamics Simulations ◽

Hiv 1

Download Full-text

Synthesis and antiproliferative activity of amino-substituted benzimidazo[1,2- $${\varvec{a}}$$ a ]quinolines as mesylate salts designed by 3D-QSAR analysis

Molecular Diversity ◽

10.1007/s11030-017-9753-8 ◽

2017 ◽

Vol 21 (3) ◽

pp. 621-636 ◽

Cited By ~ 2

Author(s):

Darko Vušak ◽

Nataša Perin ◽

Irena Martin-Kleiner ◽

Marijeta Kralj ◽

Grace Karminski-Zamola ◽

...

Keyword(s):

Antiproliferative Activity ◽

3D Qsar ◽

Qsar Analysis

Download Full-text