ChemInform Abstract: Additive-Free Decarboxylative Coupling of Cinnamic Acid Derivatives in Water: Synthesis of Allyl Amines.

ChemInform ◽  
2015 ◽  
Vol 46 (29) ◽  
pp. no-no
Author(s):  
Kyungho Park ◽  
Sunwoo Lee
Keyword(s):  
Cinnamic Acid ◽  
Cinnamic Acid Derivatives ◽  
Decarboxylative Coupling

Visible-Light-Mediated Oxidative Decarboxylative Coupling of Cinnamic Acid Derivatives with Tetrahydrofuran

Synlett ◽  
2015 ◽  
Vol 26 (20) ◽  
pp. 2849-2852 ◽  
Author(s):  
Zheng Liu ◽  
Leifeng Wang ◽  
Dong Liu ◽  
Zhigang Wang
Keyword(s):  
Visible Light ◽  
Cinnamic Acid ◽  
Cinnamic Acid Derivatives ◽  
Decarboxylative Coupling

Novel Piperazine Amides of Cinnamic Acid Derivatives as Tyrosinase Inhibitors

2018 ◽  
Vol 16 (1) ◽  
pp. 36-44 ◽  
Author(s):  
Zehra Tuğçe Gür ◽  
Fatma Sezer Şenol ◽  
Suhaib Shekfeh ◽  
İlkay Erdoğan Orhan ◽  
Erden Banoğlu ◽  
...  
Keyword(s):  
Cinnamic Acid ◽  
Active Site ◽  
Agaricus Bisporus ◽  
Biological Activities ◽  
Docking Simulation ◽  
Cinnamic Acid Derivatives ◽  
In Silico Docking ◽  
Amide Derivatives ◽  
Tyrosinase Inhibitors ◽  
Further Development

Background: A series of novel cinnamic acid piperazine amide derivatives has been designed and synthesized, and their biological activities were also evaluated as potential tyrosinase inhibitors. Methods: Compounds 9, 11 and 17 showed the most potent biological activity (IC50 = 66.5, 61.1 and 66 µM, respectively). In silico docking simulation was performed to position compound 11 into the Agaricus bisporus mushroom tyrosinase’s active site to determine the putative binding interactions. Results and Conclusion: The results indicated that compound 11 could serve as a promising lead compound for further development of potent tyrosinase inhibitors.

Evaluation of Antinociceptive and Anti-Inflammatory Activities of a New Triterpene Saponin from Bauhinia variegata Leaves

2009 ◽  
Vol 64 (11-12) ◽  
pp. 798-808 ◽  
Author(s):  
Mona A. Mohamed ◽  
Madeha R. Mammoud ◽  
Heiko Hayen
Keyword(s):  
High Resolution ◽  
Spectral Data ◽  
Cinnamic Acid ◽  
Cinnamic Acid Derivatives ◽  
Triterpene Saponin ◽  
H Nmr ◽  
Antischistosomal Activity ◽  
Bauhinia Variegata ◽  
Anti Inflammatory ◽  
C Nmr

A new triterpene saponin, named as 23-hydroxy-3α-[O-α-L-1C4-rhamnopyranosyl-(1´´4´)- O-α-L-4C1-arabinopyranosyl-oxy]olean-12-en-28-oic acid O-α-L-1C4-rhamnopyranosyl- (1´´´´´→4´´´´)-O-β-D-4C1-glucopyranosyl-(1´´´´→6´´´)-O-β-D-4C1-glucopyranosyl ester (9), was isolated from the leaves of Bauhinia variegata Linn. In addition, six flavonoid compounds along with two cinnamic acid derivatives were isolated and identified based on their chromatographic properties, and chemical and spectral data (ESI-high resolution-MSn, 1H NMR, 13C NMR, 1H-1H COSY, HSQC, and HMBC). Compound 9 was found to be nontoxic (LD50) and to have significant anti-inflammatory and antinociceptive activities. It also showed a slight antischistosomal activity.

Cinnamic Acid Derivatives as Anticancer Agents-A Review

2011 ◽  
Vol 18 (11) ◽  
pp. 1672-1703 ◽  
Author(s):  
P. De ◽  
M. Baltas ◽  
F. Bedos-Belval
Keyword(s):  
Cinnamic Acid ◽  
Anticancer Agents ◽  
Cinnamic Acid Derivatives

Asymmetric epoxidation of cinnamic acid derivatives using dioxiranes generated in situ from dehydrocholic acid

2001 ◽  
Vol 12 (8) ◽  
pp. 1113-1115 ◽  
Author(s):  
Olga Bortolini ◽  
Marco Fogagnolo ◽  
Giancarlo Fantin ◽  
Silvia Maietti ◽  
Alessandro Medici
Keyword(s):  
Cinnamic Acid ◽  
Asymmetric Epoxidation ◽  
Cinnamic Acid Derivatives ◽  
Dehydrocholic Acid
Sign in / Sign up

Export Citation Format

Share Document