ChemInform Abstract: Bi(OTf)3-Catalyzed C-H Bond Functionalization of Azaarenes for the Facile Access to Oxindoles Featuring Quaternary Carbon Centers.

ChemInform ◽  
2015 ◽  
Vol 46 (25) ◽  
pp. no-no
Author(s):  
Beili Lu ◽  
Qilin Lu ◽  
Senyang Zhuang ◽  
Jiajia Cheng ◽  
Biao Huang
Keyword(s):  
Quaternary Carbon ◽  
Bond Functionalization ◽  
Carbon Centers

scholarly journals Methodologies for the synthesis of quaternary carbon centers via hydroalkylation of unactivated olefins: twenty years of advances

2021 ◽  
Vol 17 ◽  
pp. 1565-1590
Author(s):  
Thiago S Silva ◽  
Fernando Coelho
Keyword(s):  
Double Bond ◽  
Hydrogen Atom Transfer ◽  
Transfer Reactions ◽  
Quaternary Carbon ◽  
Bond Functionalization ◽  
Quaternary Centers ◽  
Carbon Centers ◽  
Wide Availability ◽  
Hydride Hydrogen ◽  
Molecular Complexity

Olefin double-bond functionalization has been established as an excellent strategy for the construction of elaborate molecules. In particular, the hydroalkylation of olefins represents a straightforward strategy for the synthesis of new C(sp3)–C(sp3) bonds, with concomitant formation of challenging quaternary carbon centers. In the last 20 years, numerous hydroalkylation methodologies have emerged that have explored the diverse reactivity patterns of the olefin double bond. This review presents examples of olefins acting as electrophilic partners when coordinated with electrophilic transition-metal complexes or, in more recent approaches, when used as precursors of nucleophilic radical species in metal hydride hydrogen atom transfer reactions. This unique reactivity, combined with the wide availability of olefins as starting materials and the success reported in the construction of all-carbon C(sp3) quaternary centers, makes hydroalkylation reactions an ideal platform for the synthesis of molecules with increased molecular complexity.

Bi(OTf)3-catalyzed C–H bond functionalization of azaarenes for the facile access to oxindoles featuring quaternary carbon centers

RSC Advances ◽  
2015 ◽  
Vol 5 (11) ◽  
pp. 8285-8288 ◽  
Author(s):  
Beili Lu ◽  
Qilin Lu ◽  
Senyang Zhuang ◽  
Jiajia Cheng ◽  
Biao Huang
Keyword(s):  
Quaternary Carbon ◽  
Bond Functionalization ◽  
Carbon Centers ◽  
Quaternary Center

Bi(OTf)3-catalyzed sp3 C–H functionalization of 2-alkyl azaarenes to isatylidene malononitriles has been achieved to give oxindoles containing an all-carbon quaternary center.

Stereocontrolled Synthesis of Highly Functionalized Quaternary Carbon Centers: A Route to α-Substituted Serines

2009 ◽  
Vol 121 (23) ◽  
pp. 4266-4269 ◽  
Author(s):  
Xavier Ariza ◽  
Josep Cornellà ◽  
Mercè Font-Bardia ◽  
Jordi Garcia ◽  
Jordi Ortiz ◽  
...  
Keyword(s):  
Quaternary Carbon ◽  
Carbon Centers ◽  
Stereocontrolled Synthesis

Alkylation of (η6-arene) - Ru(II) complexes: Construction of benzylic quaternary carbon centers

1999 ◽  
Vol 40 (12) ◽  
pp. 2251-2254 ◽  
Author(s):  
F.Christopher Pigge ◽  
Shiyue Fang ◽  
Nigam P Rath
Keyword(s):  
Quaternary Carbon ◽  
Carbon Centers

scholarly journals Synthesis of Quaternary Carbon Centers via Hydroformylation

2010 ◽  
Vol 132 (34) ◽  
pp. 11841-11843 ◽  
Author(s):  
X. Sun ◽  
K. Frimpong ◽  
K. L. Tan
Keyword(s):  
Quaternary Carbon ◽  
Carbon Centers
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