ChemInform Abstract: Transition Metal-Free Asymmetric and Diastereoselective Allylic Alkylation Using Grignard Reagents: Construction of Vicinal Stereogenic Centers via Kinetic Resolution.

ChemInform ◽  
2015 ◽  
Vol 46 (8) ◽  
pp. no-no
Author(s):  
David Grassi ◽  
Alexandre Alexakis
Keyword(s):  
Transition Metal ◽  
Kinetic Resolution ◽  
Grignard Reagents ◽  
Allylic Alkylation ◽  
Metal Free ◽  
Stereogenic Centers

Transition metal-free asymmetric and diastereoselective allylic alkylation using Grignard reagents: construction of vicinal stereogenic centers via kinetic resolution

2014 ◽  
Vol 5 (10) ◽  
pp. 3803-3807 ◽  
Author(s):  
David Grassi ◽  
Alexandre Alexakis
Keyword(s):  
Transition Metal ◽  
Kinetic Resolution ◽  
Grignard Reagents ◽  
Allylic Alkylation ◽  
Asymmetric Allylic Alkylation ◽  
Quaternary Centers ◽  
Metal Free ◽  
Stereogenic Centers

The first transition metal-free catalyzed diastereoselective and enantioselective asymmetric allylic alkylation (AAA) has been disclosed leading to the construction of vicinal tertiary/quaternary centers via a kinetic resolution protocol starting from readily available starting materials.

Transition-Metal-Free Electrophilic Amination between Aryl Grignard Reagents andN-Chloroamines

2010 ◽  
Vol 12 (7) ◽  
pp. 1516-1519 ◽  
Author(s):  
Takuji Hatakeyama ◽  
Yuya Yoshimoto ◽  
Sujit K. Ghorai ◽  
Masaharu Nakamura
Keyword(s):  
Transition Metal ◽  
Grignard Reagents ◽  
Electrophilic Amination ◽  
Metal Free

Transition-Metal-Free Synthesis of Fluorinated Arenes from Perfluorinated Arenes Coupled with Grignard Reagents

2014 ◽  
Vol 33 (4) ◽  
pp. 1079-1081 ◽  
Author(s):  
Yunqiang Sun ◽  
Hongjian Sun ◽  
Jiong Jia ◽  
Aiqin Du ◽  
Xiaoyan Li
Keyword(s):  
Transition Metal ◽  
Grignard Reagents ◽  
Metal Free

scholarly journals Water promoted allylic nucleophilic substitution reactions of (E)-1,3 diphenylallyl acetate

2018 ◽  
Vol 20 (2) ◽  
pp. 425-430 ◽  
Author(s):  
Seema A. Ghorpade ◽  
Dinesh N. Sawant ◽  
Arwa Makki ◽  
Nagaiyan Sekar ◽  
Jörg Eppinger
Keyword(s):  
Transition Metal ◽  
Nucleophilic Substitution ◽  
Allylic Alkylation ◽  
Substitution Reactions ◽  
Allylic Amination ◽  
Metal Free ◽  
Nucleophilic Substitution Reactions ◽  
Water Based

A transition metal free, reagent free, only water based, greener protocol for the allylic alkylation, allylic amination, and O-allylation of (E)-1,3-diphenylallyl acetate is described.

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