ChemInform Abstract: Activation of Carboxylic Acids in Asymmetric Organocatalysis.

ChemInform ◽  
2014 ◽  
Vol 45 (51) ◽  
pp. no-no
Author(s):  
Mattia Riccardo Monaco ◽  
Belen Poladura ◽  
Miriam Diaz de Los Bernardos ◽  
Markus Leutzsch ◽  
Richard Goddard ◽  
...  
Keyword(s):  
Carboxylic Acids ◽  
Asymmetric Organocatalysis

The Activation of Carboxylic Acids via Self-Assembly Asymmetric Organocatalysis: A Combined Experimental and Computational Investigation

2016 ◽  
Vol 138 (44) ◽  
pp. 14740-14749 ◽  
Author(s):  
Mattia Riccardo Monaco ◽  
Daniele Fazzi ◽  
Nobuya Tsuji ◽  
Markus Leutzsch ◽  
Saihu Liao ◽  
...  
Keyword(s):  
Carboxylic Acids ◽  
Self Assembly ◽  
Computational Investigation ◽  
Asymmetric Organocatalysis

Activation of Carboxylic Acids in Asymmetric Organocatalysis

2014 ◽  
Vol 53 (27) ◽  
pp. 7063-7067 ◽  
Author(s):  
Mattia Riccardo Monaco ◽  
Belén Poladura ◽  
Miriam Diaz de Los Bernardos ◽  
Markus Leutzsch ◽  
Richard Goddard ◽  
...  
Keyword(s):  
Carboxylic Acids ◽  
Asymmetric Organocatalysis

A convenient preparative method for 1,4-diketones from carboxylic acids

1977 ◽  
Vol 27 (1) ◽  
pp. 117-120
Author(s):  
Shoji Watanabe ◽  
Tsutomu Fujita ◽  
Kyoichi Suga ◽  
Haruhiko Abe
Keyword(s):  
Carboxylic Acids ◽  
Preparative Method

Probing The Resolution of 2-Alkoxy and 2-Aryloxy Carboxylic Acids

2006 ◽  
Author(s):  
Jason Eames ◽  
Ewan Boyd ◽  
Sameer Chavda
Keyword(s):  
Carboxylic Acids

Ligand-Enabled γ-C(sp3)–H Olefination of Free Carboxylic Acids

2020 ◽  
Author(s):  
Kiron Kumar Ghosh ◽  
Alexander Uttry ◽  
Francesca Ghiringhelli ◽  
Arup Mondal ◽  
Manuel van Gemmeren
Keyword(s):  
Reaction Mechanism ◽  
Carboxylic Acids ◽  
Michael Addition ◽  
Kinetic Studies ◽  
Wide Range ◽  
Palladium Catalyzed

We report the ligand enabled C(sp3)–H activation/olefination of free carboxylic acids in the γ-position. Through an intramolecular Michael-addition, δ-lactones are obtained as products. Two distinct ligand classes are identified that enable the challenging palladium-catalyzed activation of free carboxylic acids in the γ-position. The developed protocol features a wide range of acid substrates and olefin reaction partners and is shown to be applicable on a preparatively useful scale. Insights into the underlying reaction mechanism obtained through kinetic studies are reported.<br>

Reversing Reactivity: Stereoselective Desulfurative β-O-Glycosylation of Anomeric Thiosugars with Carboxylic Acids Under Copper or Cobalt Catalysis

2019 ◽  
Author(s):  
Samir Messaoudi ◽  
Nedjwa Bennai ◽  
Amelie Chabrier ◽  
Maha Fatthalla ◽  
Expédite Yen-Pon ◽  
...  
Keyword(s):  
Carboxylic Acids ◽  
Late Stage ◽  
Catalytic Amount ◽  
Broad Scope ◽  
Wide Range ◽  
Glycosylation Reaction

We have discovered a new mode of reactivity of 1-thiosugars in the presence of Cu(II) or Co(II) for a stereoselective <i>O</i>-glycosylation reaction. The process involves the use of a catalytic amount of Cu(acac)2 or Co(acac)2 and Ag2CO3 as an oxidant in α,α,α-trifluorotoluene (TFT). Moreover, this protocol turned out to have a broad scope, allowing to prepare a wide range of com-plex substituted <i>O</i>-glycoside esters in good to excellent yields with an exclusive β-selectivity. The late-stage modification of phar-maceuticals by this method was also demonstrated.

Sign in / Sign up

Export Citation Format

Share Document