ChemInform Abstract: Near-Infrared Light-Responsive Nanomaterials in Cancer Therapeutics

ChemInform ◽  
2014 ◽  
Vol 45 (46) ◽  
pp. no-no
Author(s):  
Vijayakumar Shanmugam ◽  
S. Selvakumar ◽  
Chen-Sheng Yeh
Keyword(s):  
Near Infrared ◽  
Cancer Therapeutics ◽  
Infrared Light ◽  
Near Infrared Light

Near-infrared light-responsive nanomaterials in cancer therapeutics

2014 ◽  
Vol 43 (17) ◽  
pp. 6254-6287 ◽  
Author(s):  
Vijayakumar Shanmugam ◽  
S. Selvakumar ◽  
Chen-Sheng Yeh
Keyword(s):  
Cancer Therapy ◽  
Near Infrared ◽  
Cancer Therapeutics ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Site Specific

Near-infrared light sensitive nanomaterials provide ideal nanoplatforms in site specific noninvasive cancer therapy.

scholarly journals Near-infrared light–triggered platelet arsenal for combined photothermal-immunotherapy against cancer

2021 ◽  
Vol 7 (13) ◽  
pp. eabd7614
Author(s):  
Yanlin Lv ◽  
Feng Li ◽  
Shuang Wang ◽  
Guihong Lu ◽  
Weier Bao ◽  
...  
Keyword(s):  
Near Infrared ◽  
Vascular Endothelial Cells ◽  
Immunological Response ◽  
Cancer Therapeutics ◽  
Tumor Xenograft ◽  
Infrared Light ◽  
Vascular Endothelial ◽  
Active Components ◽  
Near Infrared Light ◽  
Sophisticated Model

To address long-standing issues with tumor penetration and targeting among cancer therapeutics, we developed an anticancer platelet-based biomimetic formulation (N+R@PLTs), integrating photothermal nanoparticles (N) and immunostimulator (R) into platelets (PLTs). Exploiting the aggregative properties of platelets and high photothermal capacity, N+R@PLTs functioned as an arsenal by targeting defective tumor vascular endothelial cells, accumulating in a positive feedback aggregation cascade at sites of acute vascular damage induced by N-generated local hyperthermia, and subsequently secreting nanosized proplatelets (nPLTs) to transport active components to deep tumor tissue. The immunostimulator augmented the immunogenicity of antigens released from ablated tumors, inducing a stronger immunological response to attack residual, metastatic, and recurrent tumors. Following activation by low-power near-infrared light irradiation, the photothermal and immunological components synergistically provide exceptionally high therapeutic efficacy across nine murine models that mimicked a range of clinical requirements, and, most notably, a sophisticated model based on humanized mouse and patient-derived tumor xenograft.

An ordered copper nanowell-array film with near-perfect broadband absorption from ultraviolet to near-infrared light

2020 ◽  
Vol 59 (11) ◽  
pp. 110906
Author(s):  
Juan Shen ◽  
Yong Ren ◽  
Xinxin Zhu ◽  
Min Mao ◽  
Quan Zhou ◽  
...  
Keyword(s):  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Broadband Absorption

scholarly journals Recent Near-Infrared Light-Activated Nanomedicine toward Precision Cancer Therapy

2021 ◽  
Author(s):  
Xiaowei Luan ◽  
Yongchun Pan ◽  
Yanfeng Gao ◽  
Yujun Song
Keyword(s):  
Cancer Therapy ◽  
Near Infrared ◽  
Infrared Light ◽  
Human Society ◽  
Near Infrared Light ◽  
History Of ◽  
The Universe

Light has witnessed the history of mankind and even the universe. It is of great significances to the life of human society, contributing to energy, agriculture, communication, and much more....

scholarly journals Au–ZnO Conjugated Black Phosphorus as a Near-Infrared Light-Triggering and Recurrence-Suppressing Nanoantibiotic Platform against Staphylococcus aureus

Pharmaceutics ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 52
Author(s):  
Atanu Naskar ◽  
Sohee Lee ◽  
Kwang-sun Kim
Keyword(s):  
Staphylococcus Aureus ◽  
Bacterial Infections ◽  
Near Infrared ◽  
Au Nanoparticles ◽  
Synthesis Method ◽  
Antibacterial Properties ◽  
Black Phosphorus ◽  
Infrared Light ◽  
Resistant Bacteria ◽  
Near Infrared Light

Antibiotic therapy is the gold standard for bacterial infections treatment. However, the rapid increase in multidrug-resistant (MDR) bacterial infections and its recent use for secondary bacterial infections in many COVID-19 patients has considerably weakened its treatment efficacy. These shortcomings motivated researchers to develop new antibacterial materials, such as nanoparticle-based antibacterial platform with the ability to increase the chances of killing MDR strains and prevent their drug resistance. Herein, we report a new black phosphorus (BP)-based non-damaging near-infrared light-responsive platform conjugated with ZnO and Au nanoparticles as a synergistic antibacterial agent against Staphylococcus aureus species. First, BP nanosheets containing Au nanoparticles were assembled in situ with the ZnO nanoparticles prepared by a low-temperature solution synthesis method. Subsequently, the antibacterial activities of the resulting Au–ZnO–BP nanocomposite against the non-resistant, methicillin-resistant, and erythromycin-resistant S. aureus species were determined, after its photothermal efficacy was assessed. The synthesized nanocomposite exhibited excellent anti-S. aureus activity and good photothermal characteristics. The non-resistant S. aureus species did not produce drug-resistant bacteria after the treatment of multiple consecutive passages under the pressure of the proposed nanoantibiotic, but rapidly developed resistance to erythromycin. This work clearly demonstrates the excellent photothermal antibacterial properties of Au–ZnO–BP nanocomposite against the MDR S. aureus species.

π-Conjugated Copolymers Composed of Boron Formazanate and Their Application for a Wavelength Converter to Near-Infrared Light

2021 ◽  
Vol 54 (4) ◽  
pp. 1934-1942
Author(s):  
Yuki Kawano ◽  
Yoshinori Ito ◽  
Shunichiro Ito ◽  
Kazuo Tanaka ◽  
Yoshiki Chujo
Keyword(s):  
Near Infrared ◽  
Infrared Light ◽  
Wavelength Converter ◽  
Near Infrared Light ◽  
Conjugated Copolymers

Visible and near-infrared light activated azo dyes

2021 ◽  
Author(s):  
Huijuan Chen ◽  
Weijie Chen ◽  
Yan Lin ◽  
Yuan Xie ◽  
Sheng Hua Liu ◽  
...  
Keyword(s):  
Azo Dyes ◽  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light
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