ChemInform Abstract: Sulfuryl Chloride as an Efficient Initiator for the Metal-Free Aerobic Cross-Dehydrogenative Coupling Reaction of Tertiary Amines.

ChemInform ◽  
2014 ◽  
Vol 45 (45) ◽  
pp. no-no
Author(s):  
Arata Tanoue ◽  
Woo-Jin Yoo ◽  
Shu Kobayashi
Keyword(s):  
Coupling Reaction ◽  
Sulfuryl Chloride ◽  
Tertiary Amines ◽  
Metal Free ◽  
Dehydrogenative Coupling

Metal-Free Synthesis of α-Aminophosphonates from Tertiary Amines and P(O)H Compounds via a Cross-Dehydrogenative Coupling Reaction

Synlett ◽  
2018 ◽  
Vol 29 (20) ◽  
pp. 2697-2700 ◽  
Author(s):  
Guo Tang ◽  
Binzhou Lin ◽  
Guozhang Lu ◽  
Rongcan Lin ◽  
Yiqun Cui ◽  
...  
Keyword(s):  
Tertiary Amine ◽  
Coupling Reaction ◽  
Transition Metal Catalysts ◽  
Tertiary Amines ◽  
Butyl Hydroperoxide ◽  
Metal Free ◽  
Tert Butyl ◽  
Dehydrogenative Coupling ◽  
Tert Butyl Hydroperoxide ◽  
Aromatic And Aliphatic Amines

The various α-aminophosphonates have been prepared from tertiary aromatic and aliphatic amines with P(O)H compounds via a tert-butyl hydroperoxide mediated cross-dehydrogenative coupling reaction, eliminating the need for transition-metal catalysts. The oxidation of tertiary amine by tert-butyl hydroperoxide generates an iminium cation intermediate. A further addition of P(O)H compound to iminium cation gives the desired product.

ChemInform Abstract: DIAD-Mediated Metal-Free Cross Dehydrogenative Coupling Between Tertiary Amines and α-Fluorinated Sulfones.

ChemInform ◽  
2013 ◽  
Vol 44 (44) ◽  
pp. no-no
Author(s):  
Weizhou Huang ◽  
Chuanfa Ni ◽  
Yanchuan Zhao ◽  
Jinbo Hu
Keyword(s):  
Tertiary Amines ◽  
Metal Free ◽  
Dehydrogenative Coupling

(Diacetoxyiodo)benzene-Mediated Transition-Metal-Free Amination of C(sp3)–H Bonds Adjacent to Heteroatoms with Azoles: Synthesis of N-Alkylated Azoles

Synlett ◽  
2018 ◽  
Vol 29 (18) ◽  
pp. 2432-2436 ◽  
Author(s):  
Can Jin ◽  
Weike Su ◽  
Bin Sun ◽  
Zhiyang Yan
Keyword(s):  
Free Radical ◽  
Transition Metal ◽  
Coupling Reaction ◽  
Metal Catalyst ◽  
Metal Free ◽  
Alternative Method ◽  
Dehydrogenative Coupling ◽  
Wide Range ◽  
Ready Access

A novel PhI(OAc)2-mediated cross-dehydrogenative coupling reaction of α-C(sp3)–H bonds adjacent to a hetero atom with various azoles has been developed, which provides an alternative method for constructing C–N bonds with high atom efficiency. This new protocol requires no metal catalyst and it provides ready access to a wide range of N-alkylated azole derivatives in moderate to excellent yields by using commercially available PhI(OAc)2 as the sole oxidant. Furthermore, the method is effective on a gram scale, which highlights the practicality of this transformation. The result of radical-captured experiments indicated that the transformation might involve a free-radical pathway.

Regioselective transition metal-free acylation of coumarins via cross-dehydrogenative coupling reaction of coumarins and aldehydes

2016 ◽  
Vol 57 (33) ◽  
pp. 3701-3705 ◽  
Author(s):  
Mehdi Adib ◽  
Saideh Rajai-Daryasarei ◽  
Rahim Pashazadeh ◽  
Mahnaz Tajik ◽  
Peiman Mirzaei
Keyword(s):  
Transition Metal ◽  
Coupling Reaction ◽  
Metal Free ◽  
Dehydrogenative Coupling

A Metal-Free Cross-Dehydrogenative Coupling Reaction of Amides to Access N-Alkylazoles

Synlett ◽  
2016 ◽  
Vol 27 (19) ◽  
pp. 2705-2708 ◽  
Author(s):  
Shengmei Guo ◽  
Hu Cai ◽  
Zheng Zhu ◽  
Yufeng Wang ◽  
Mingmeng Yang ◽  
...  
Keyword(s):  
Coupling Reaction ◽  
Metal Free ◽  
Dehydrogenative Coupling
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