ChemInform Abstract: [RhIII(Cp*)]-Catalyzed ortho-Selective Direct C(sp2)-H Bond Amidation/Amination of Benzoic Acids by N-Chlorocarbamates and N-Chloromorpholines. A Versatile Synthesis of Functionalized Anthranilic Acids.

ChemInform ◽  
2014 ◽  
Vol 45 (40) ◽  
pp. no-no
Author(s):  
Fo-Ning Ng ◽  
Zhongyuan Zhou ◽  
Wing-Yiu Yu
Keyword(s):  
Benzoic Acids ◽  
Anthranilic Acids

Synthesis and anti-inflammatory evaluation of N -sulfonyl anthranilic acids via Ir(III)-catalyzed C–H amidation of benzoic acids

2017 ◽  
Vol 27 (10) ◽  
pp. 2129-2134 ◽  
Author(s):  
Sang Hoon Han ◽  
Hyo Sun Suh ◽  
Hyeim Jo ◽  
Yongguk Oh ◽  
Neeraj Kumar Mishra ◽  
...  
Keyword(s):  
Benzoic Acids ◽  
Anthranilic Acids ◽  
Anti Inflammatory

scholarly journals Fischer indolisation of N-(α-ketoacyl)anthranilic acids into 2-(indol-2-carboxamido)benzoic acids and 2-indolyl-3,1-benzoxazin-4-ones and their NMR study

2014 ◽  
Vol 12 (47) ◽  
pp. 9650-9664 ◽  
Author(s):  
Karel Proisl ◽  
Stanislav Kafka ◽  
Damijana Urankar ◽  
Martin Gazvoda ◽  
Roman Kimmel ◽  
...  
Keyword(s):  
Benzoic Acids ◽  
New Approach ◽  
Nmr Study ◽  
Anthranilic Acids

A new approach to 2-indolyl functionalized anthranilic acids and 3,1-benzoxazin-4-ones.

Reaction between anthranilic acids, salicylaldehydes and isocyanides in water: an efficient synthesis of 2-{[2-(alkylimino)-1-benzofuran-3-yliden]amino}benzoic acids

2010 ◽  
Vol 51 (1) ◽  
pp. 27-29 ◽  
Author(s):  
Mehdi Adib ◽  
Mohammad Mahdavi ◽  
Sharareh Bagherzadeh ◽  
Long-Guan Zhu ◽  
Mehdi Rahimi-Nasrabadi
Keyword(s):  
Benzoic Acids ◽  
Efficient Synthesis ◽  
Anthranilic Acids

Substituted N,N-Dimethyl-3-(phenylthio)- and -4-(phenylthio)benzylamines

1992 ◽  
Vol 57 (1) ◽  
pp. 194-203 ◽  
Author(s):  
Karel Šindelář ◽  
Vojtěch Kmoníček ◽  
Marta Hrubantová ◽  
Zdeněk Polívka
Keyword(s):  
Serotonin Receptors ◽  
Hydrobromic Acid ◽  
Antidepressant Activity ◽  
Benzoic Acids ◽  
Lithium Aluminium Hydride ◽  
Acid Chlorides ◽  
Activity Inhibition ◽  
Lithium Aluminium ◽  
The Brain

(Arylthio)benzoic acids IIa - IIe and VIb - VId were transformed via the acid chlorides to the N,N-dimethylamides which were reduced either with diborane "in situ" or with lithium aluminium hydride to N,N-dimethyl-(arylthio)benzylamines Ia - Ie and Vb - Vd. Leuckart reaction of the aldehydes IX and X with dimethylformamide and formic acid afforded directly the amines Va and Ve. Demethylation of the methoxy compounds Ia and Ve with hydrobromic acid resulted in the phenolic amines If and Vf. The most interesting N,N-dimethyl-4-(phenylthio)benzylamine (Va) hydrochloride showed affinity to cholinergic and 5-HT2 serotonin receptors in the rat brain and some properties considered indicative of antidepressant activity (inhibition of serotonin re-uptake in the brain and potentiation of yohimbine toxicity in mice).

Kinetics and Mechanism of Decomposition of 1,3-Bis(4-methylphenyl)triazene Catalyzed with Substituted Benzoic Acids in 25% Aqueous Methanol-General or Specific Catalysis?

1994 ◽  
Vol 59 (9) ◽  
pp. 2029-2041
Author(s):  
Oldřich Pytela ◽  
Taťjana Nevěčná
Keyword(s):  
Benzoic Acids ◽  
Hammett Equation ◽  
Aqueous Methanol ◽  
Mechanism Of Decomposition ◽  
Kinetics Of Decomposition ◽  
Independent Variable ◽  
Amino Derivatives ◽  
Substituted Benzoic Acids ◽  
The Individual ◽  
Kinetics Of

The kinetics of decomposition of 1,3-bis(4-methylphenyl)triazene catalyzed with 13 substituted benzoic acids of various concentrations have been measured in 25 vol.% aqueous methanol at 25.0 °C. The rate constants observed (297 data) have be used as values of independent variable in a series of models of the catalyzed decomposition. For the catalytic particles were considered the undissociated acid, its conjugated base, and the proton in both the specific and general catalyses. Some models presumed formation of reactive or nonreactive complexes of the individual reactants. The substituent effect is described by the Hammett equation. The statistically best model in which the observed rate constant is a superposition of a term describing the dependence on proton concentration and a term describing the dependence on the product of concentrations of proton and conjugated base is valid with the presumption of complete proton transfer from the catalyst acid to substrate, which has been proved. The behaviour of 4-dimethylamino, 4-amino, and 3-amino derivatives is anomalous (lower catalytic activity as compared with benzoic acid). This supports the presumed participation of conjugated base in the title process.

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