ChemInform Abstract: C3-Symmetric Cinchonine-Squaramide-Catalyzed Asymmetric Chlorolactonization of Styrene-Type Carboxylic Acids with 1,3-Dichloro-5,5-dimethylhydantoin: An Efficient Method to Chiral Isochroman-1-ones.
A rapid and efficient method for ‘one-pot’ synthesis of pyrazoles from (hetero)arenes and carboxylic acids via successive formation of ketones and β-diketones followed by heterocyclization with hydrazine has been developed.
Based on radical sulfur dioxide insertion and fluorination strategy, we have developed an efficient method for aliphatic sulfonyl fluoride synthesis from abundant carboxylic acid, reductant, sulfur dioxide surrogate and electrophilic...
A simple and efficient method to obtain α-xanthyl ketones from α-diazoketones is described. The reaction proceed through a protonation/nucleophilic substitution sequence with p-toluenesulfonic acid and potassium ethyl xanthogenate as nucleophile. As α-diazoketones can be readily synthesized from ubiquitous carboxylic acids, a broad variety of xanthates can be obtained, including those from natural occurring substrates