ChemInform Abstract: Ruthenium(II)/Chiral Broensted Acid Co-Catalyzed Enantioselective Four-Component Reaction/Cascade Aza-Michael Addition for Efficient Construction of 1,3,4-Tetrasubstituted Tetrahydroisoquinolines.

ChemInform ◽  
2014 ◽  
Vol 45 (29) ◽  
pp. no-no
Author(s):  
Jun Jiang ◽  
Xiaochu Ma ◽  
Changge Ji ◽  
Zhenqiu Guo ◽  
Taoda Shi ◽  
...  
2015 ◽  
Vol 51 (52) ◽  
pp. 10554-10557 ◽  
Author(s):  
Jianlin Zhang ◽  
Yulong Zhang ◽  
Lili Lin ◽  
Qian Yao ◽  
Xiaohua Liu ◽  
...  

The asymmetric Michael addition/desymmetrization reaction catalyzed by a N,N′-dioxide-Sc(iii) complex was realized, leading to the succinimides with two kinds of stereogenic elements—atom chirality and axial chirality in up to 99% yield, 99% ee and >19 : 1 d.r.


2015 ◽  
Vol 13 (19) ◽  
pp. 5460-5466 ◽  
Author(s):  
Zhi-Yong Xue ◽  
Zhi-Min Song ◽  
Chun-Jiang Wang

Cu(i)-catalyzed asymmetric Michael addition of cyclic ketimino esters with alkylidene malonates has been developed for efficient construction of β-branched α-amino acids containing adjacent quaternary and tertiary stereogenic centers in good yields with excellent diastereo-/enantioselectivities.


2000 ◽  
Vol 24 (4) ◽  
pp. 467-476 ◽  
Author(s):  
Sabine Vollenweider ◽  
Hans Weber ◽  
Stephanie Stolz ◽  
Aurore Chetelat ◽  
Edward E. Farmer
Keyword(s):  

2015 ◽  
Vol E98.B (7) ◽  
pp. 1276-1283 ◽  
Author(s):  
Nam-Su JHO ◽  
Ku-Young CHANG ◽  
Do-Won HONG

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